Publications
Ishitani T, Hirao T, Suzuki M, Isoda M, Ishitani S, Harigaya K, Kitagawa M, Matsumoto K, Itoh M.
Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex.
Nature Cell Biol. 12, 278-285. (2010)
Higashi M, Ishikawa C, Yu J, Toyoda A, Kawana H, Kurokawa K, Matsuda M, Kitagawa M, Harigaya K.
Human Mena associates with Rac1 small GTPase in glioblastoma cell lines.
PLoS One. 4(3):e4765. Epub Mar 11.(2009)
Toyoda A, Kawana H, Azuhata K, Yu J, Omata A, Kishi H, Higashi M, Harigaya K.
Aberrant expression of human ortholog of mammalian enabled (hMena) in human colorectal carcinomas: implications for its role in tumor progression.
Int J Oncol. Jan;34(1):53-60.(2009)
Harima A, Nakaseko C, Yokota A, Kitagawa M, Morimoto C, Harigaya K, Saito Y.
Fibronectin promotes cell proliferation of human pre-B cell line via its interactions with VLA-4 and VLA-5.
Hematology. Aug;13(4):236-43.(2008)
Jiang M, Bujo H, Ohwaki K, Unoki H, Yamazaki H, Kanaki T, Shibasaki M, Azuma K, Harigaya K, Schneider WJ, Saito Y.
AngII, stimulated migration of vascular SMC is dependent on LR11.
J Clin Invest. Aug;118(8):2733-46.(2008)
Kawana H, Karaki H, Higashi M, Miyazaki M, Hilberg F, Kitagawa M, Harigaya K
CD44, Suppresses LR-Mediated Inflammation.
J Immunol. 180(6),4235-45.(2008)
Fukami M., Wada Y., Okada M., Kato F., Katsumata N., Baba T., Morohashi K.-i., Laporte J., Kitagawa M., and Ogata T.
Mastermind-like domain containing 1 (MAMLD1 or CXorf6) transactivates the Hes3 promoter, augments testosterone production, and contains the SF1 target sequence.
J. Biol. Chem. 283, 5525-5532.(2008)
Furuichi Y, Goi K, Inukai T, Sato H, Nemoto A, Takahashi K, Akahane K, Hirose K, Honna H, Kuroda I, Zhang X, Kagami K, Hayashi Y, Harigaya K, Nakazawa S, Sugita K
Fms-like tyrosine kinase 3 ligand stimulation, induces MLL-rearranged leukemia cells into quiescence resistant to antileukemic agents.
Cancer Res. 67(20),9852-61.(2007)
Takami Y, Higashi M, Kumagai S, Kuo PC, Kawana H, Koda K, Miyazaki M, Harigaya K.
The Activity of RhoA is Correlated with Lymph Node Metastasis in Human Colorectal
Cancer. Dig Dis Sci. 53(2),467-73.(2008)
Oyama T, Harigaya K, Muradil A, Hozumi K, Habu S, Oguro H, Iwama A, Matsuno K, Sakamoto R, Sato M, Yoshida N, Kitagawa M.
Mastermind-1 is required for Notch signal-dependent steps in lymphocyte development in vivo.
Proc Natl Acad Sci USA.104:9764-9.(2007)
Okajima Y, Hirai A, Higashi M, Harigaya K.
Vasospastic angina in a 13-year-old female patient whose only symptom was toothache.
Pediatr Cardiol.28:68-71.(2007)
Liu TL, Shimada H, Ochiai T, Shiratori T, Lin SE, Kitagawa M, Harigaya K, Maki M, Oka M, Abe T, Takiguchi M, Hiwasa T.
Enhancement of chemosensitivity toward peplomycin bycalpastatin-stabilized NF-kB p65 in esophageal carcinoma cells, possible involvement of Fas/Fas-L synergism.
Apoptosis. 11,(6):1025-1037.(2006)
Matsushita K, Tomonaga T, Shimada H, Shioya A, Higashi M, Matsubara H, Harigaya K, Nomura F, Libutti D, Levens D, Ochiai T.
An essential role of alternative splicing of c-myc suppressor FUSE-binding protein-interacting repressor in carcinogenesis.
Cancer Res. 66,1409-1417.(2006)
Ishikawa HO, Higashi S, Ayukawa T, Sasamura T, Kitagawa M, Harigaya K, Aoki K, Ishida N, Sanai Y, Matsuno K.
Notch deficiency implicated in the pathogenesis of congenital disorder of glycosylation IIc.
Proc Natl Acad Sci USA. 102,18532-18537.(2005)
Ishii G, Sangai T, Ito T, Hasebe T, Endoh Y, Sasaki H, Harigaya K, Ochiai A.
In vivo and in vitro characterization of human fibroblasts recruited selectively into human cancer stroma.
Int J Cancer. May17.(2005)
Murai S, Umemiya T, Seiki M, Harigaya K.
Expression and localization of membrane-type-1 matrix metalloproteinase, CD44, and laminin-5gamma2 chain during colorectal carcinoma tumor progression.
Virchows Arch. 445(3):271-8
Ezawa H, Yoneyama R, Kandatsu S, Yoshikawa K, Tsujii H, Harigaya K.
Introduction of autopsy imaging redefines the concept of autopsy, 37 cases of clinical experience.
Pathol Int. 53(12):865-73
Harigaya K.
Role of CD44 and MT1-MMP in colorectal cancer invasion and metastasis.
Nippon Rinsho. Suppl. 7:111-5
Hiwasa T., Shimada H., Sakaida T., Kitagawa M., Kuroiwa N., Ochiai T., and Takiguchi M.
Drug-sensitivity pattern analysis for study of functional relationship between gene products.
FEBS Lett. 552, 177-183.(2003)
Sasamura T, Sasaki N, Miyashita F, Nakao S, Ishikawa H.O, Ito M, Kitagawa M, Harigaya K, Spana E, Bilder D, Perrimon, N, Matsuno K.
Neurotic, a novel maternal neur ogenic gene, encodes an O-fucosyltransferase that is essential for Notch- Delta interations.
Development, 130,4785-4795.(2003)
Yagata H, Harigaya K, Suzuki M, Nagashima T, Hashimoto H. Ishii G, Miyazaki M, Nakajima N. Mikata A.
Comedonecrosis is an unfavorable maker in node-negative invasive breast carcinoma.
Pathol Int. 53:501-506.(2003)
Takeuchi Y, Watanabe S, Ishii G, Takeda S, Nakayama K, Fukumoto S, Kaneta, Y, Inoue D, Matsumoto T, Harigaya K, Fujita T
Interleukin-11 as a stimulatory factor for bone formation prevents bone loss with advancing age in mice.
J Biol Chem. 277:49011-49018.(2002)
Lin S, Oyama T, Nagase T, Harigaya K, Kitagawa M.
Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling.
J Biol Chem. 277: 50612-50620.(2002)
Fujita Y, Kitagawa M, Nakamura S, Azuma K, Ishii G, Higashi M, Kishi H, Hiwasa T, Koda K, Nakajima N, Harigaya K.
CD44 signaling through focal adhesion kinase and its anti-apoptotic effect.
FEBS Lett. 528:101-108.(2002)
Isobe K, Tamaru J, Nakamura S, Harigaya K, Mikata A, Ito H.
VH gene analysis n sporadic Burkitt Ős lymphoma, somatic mutation and intraclonal diversity with special reference to the tumor cells involoving germinal centre.
Leuk Lymphoma. 43:159-164.(2002)
Kito H, Suzuki H, Ichikawa T, Sekita N, Kamiya N, Akakura K, Igarashi T, Nakayama T, Watanabe M, Harigaya K, Ito H.
Hypermethylation of the CD44 gene is associated with progression and metastasis of human prostate cancer.
Prostate. Oct 1;49(2):110-5.(2001)
Saeki N, Nagano O, Sakaida T, Murai H, Kubota M, Yamaura A, Kitou H, Harigaya K, Tatsuno I.
Recurrent neurohypophyseal germinoma causing invasion localized to temporal bone marrow-unreported neuroimaging studies compared to autopsy findings.
Acta Neurochir (Wien). 143(4):407-11. (2001) `No abstract available.
Kitagawa M, Oyama T, Kawashima T, Yedvobnick B, Kumar A, Matsuno K, Harigaya K.
A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters.
Mol Cell Biol. Jul;21(13):4337-46.(2001)
Xie B., Zhao J., Kitagawa M., Durbin J., Madri J. A., Guan J.-L. and Fu X.-Y.
Focal adhesion kinase activates Stat1 in integrin-mediated cell migration and adhesion.
J. Biol. Chem. 276:19512-19523.(2001)
Watanabe G., Kaganoi J., Imamura M., Shimada Y., Itami A., Uchida S., Sato F. and Kitagawa M.
Progression of esophageal carcinoma by loss of EGF-STAT1 pathway.
Cancer J. 7:132-139.(2001)
Qiang YW, Kitagawa M, Higashi M, Ishii G, Morimoto C, Harigaya K.
Activation of mitogen-activated protein kinase through alpha5/beta1 integrin is required for cell cycle progression of B progenitor cell line, Reh, on human marrow stromal cells.
Exp Hematol. Oct;28(10):1147-57.(2000)
Tamaru JI, Kawana H, Takahashi Y, Takahashi N, Isobe K, Hirai A, Saito Y, Harigaya K, Itoyama S, Mikata A.
Expression of Cell Cycle Regulating Proteins in an Unusual Transformation of Mantle Cell Lymphoma
Leuk Lymphoma. Dec;36(1-2):128-137.(1999)
Yokota A, Ishii G, Sugaya Y, Nishimura M, Saito Y, Harigaya K.
Potential use of serum CD44 as an indicator of tumour progression in acute leukemia.
Hematol Oncol. Dec;17(4):161-8.(1999)
Tamaru J, Kawana H, Takahashi Y, Takahashi N, Isobe K, Hirai A, Saito Y, Harigaya K, Itoyama S, Mikata A.
Expression of cell cycle regulating proteins in an unusual transformation of mantle cell lymphoma.
Leuk Lymphoma. Dec;36(1-2):129-37.(1999)
Sekita T, Tamaru JI, Isobe K, Harigaya K, Masuoka S, Katayama T, Kobayashi M, Mikata A.
Diffuse large B cell lymphoma expressing the natural killer cell marker CD56.
Pathol Int. Aug;49(8):752-8.(1999)
Yokota A, Ishii G, Sugaya Y, Nishimura M, Saito Y, Harigaya K.
Expression of exon v6-containing CD44 isoforms is related to poor prognosis of acute myelocytic leukemia.
Hematol Oncol. Dec;16(4):131-41.(1998)
Isobe K, Tamaru J, Harigaya K, Mikata A, Ito H.
Clinicopathological evaluation of the Revised European-American Classification of Lymphoid Neoplasms (REAL) in Japan.
Leuk Lymphoma. Jun;34(1-2):143-9.(1999)
Matsumoto M., Tanaka N., Harada H., Kimura T., Yokochi T., Kitagawa M., Schindler C. and Taniguchi T.
Activation of the transcription factor ISGF3 by interferon-g.
Biol. Chem. 380:699-703.(1999)
Li C., Chen L., Iwata T., Kitagawa M., Fu X.-Y. and Deng C.-X.
A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors.
Hum. Mol. Gen. 8:35-44.(1999)
Kawana H, Tamaru J, Tanaka T, Hirai A, Saito Y, Kitagawa M, Mikata A, Harigaya K, Kuriyama T.
Role of p27Kip1 and cyclin-dependent kinase 2 in the proliferation of non-small cell lung cancer.
Am J Pathol. Aug;153(2):505-13.(1998)
Ezawa H, Harigaya K, Ishii G, Nakajima N, Mikata A.
12-O-tetradecanoylphorbol-13-acetate (TPA) downregulates expression of CD30 in erythroleukemia cell line K562.
Hematol Oncol. Aug;15(3):151-61.(1997)
Akasaka T, Tsuji K, Kawahira H, Kanno M, Harigaya K, Hu L, Ebihara Y, Nakahata T, Tetsu O, Taniguchi M, Koseki H.
The role of mel-18, a mammalian Polycomb group gene, during IL-7-dependent proliferation of lymphocyte precursors.
Immunity. 7(1):135-46.(1997)
Chin Y. E., Kitagawa M., Kuida K., Flavell R. A. and Fu X.-Y.
Activation of the STAT signaling pathway can cause expression of Caspase 1 and apoptosis.
Mol. Cell. Biol. 17:5328-5337.(1997)
Su W.-C. S., Kitagawa M., Xue N., Xie B., Garofalo S., Cho J., Deng C., Horton W. A. and Fu X.-Y.
Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism.
Nature. 386:288-292.(1997)
Hatake K, Ohtsuki T, Uwai M, Takahashi H, Izumi T, Yoshida M, Kanai N, Saito K, Harigaya K, Miura Y.
Tretinoin induces bone marrow collagenous fibrosis in acute promyelocytic leukaemia: new adverse, but reversible effect.
Br J Haematol. Jun;93(3):646-9.(1996)
Shibayama H, Tagawa S, Hattori H, Harigaya K, Taga T, Machii T, Kitani T.
Interleukin-6 inhibits the chemotaxis of human malignant plasma cell lines.
Br J Haematol. Jun;93(3):534-41.(1996)
17. Takano H, Harigaya K, Ishii G, Sugaya Y, Soeta S, Nunoyama T, Shirasawa H, Shimizu K, Tokita H, Simizu B, Mikata A, Sekiya S.
Interleukin-6 (IL-6) production in carcinoma of the cervix.
Arch Gynecol Obstet. 258(1):25-33.(1996)
Harada H., Matsumoto M., Sato M., Kashiwazaki Y., Kimura T., Kitagawa M., Yokochi T., Tan R. S. P., Takasugi T., Kadokawa Y., Schindler C., Schreiber R. D., Noguchi S. and Taniguchi T.
Regulation of IFN--a/b genes; Evidence for dual function of the transcription factor complex, ISGF3 in the production and action of IFN-a/b.
Genes to Cells. (1996)
Chin Y. E., Kitagawa M., Su W.C.S., You Z.H., Iwamoto Y. and Fu X.Y.
Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21WAF1/CIP1 mediated by STAT1.
Science. 272:719-722.(1996)
Ishii G, Harigaya K, Soeta S, Mikata A.
VLA-4-dependent adhesion in follicular non-Hodgkin's lymphomas.
Hematol Pathol. 9(3-4):155-69.(1995)
Kawakami T., Matsumoto M., Sato M., Harada H., Taniguchi T. and Kitagawa M.
Possible involvement of the transcription factor ISGF3g in virus-induced expression of the IFN-b gene.
FEBS lett. 358:225-229.(1995)
Nakajima H, Kizaki M, Sonoda A, Mori S, Harigaya K, Ikeda Y.
Retinoids (all-trans and 9-cis retinoic acid) stimulate production of macrophage colony-stimulating factor and granulocyte-macrophage colony-stimulating factor by human bone marrow stromal cells.
Blood. Dec 15;84(12):4107-15.(1994)
Watari K, Ozawa K, Tajika K, Tojo A, Tani K, Kamachi S, Harigaya K, Takahashi T, Sekiguchi S, Nagata S, et al.
Production of human granulocyte colony stimulating factor by various kinds of stromal cells in vitro detected by enzyme immunoassay and in situ hybridization.
Stem Cells. Jul;12(4):416-23.(1994)
Ohtsuki T, Ikeda M, Hatake K, Tomizuka H, Hoshino Y, Suzu S, Harigaya K, Motoyoshi K, Miura Y.
Quantitative analysis of the two macrophage colony-stimulating factor mRNA expressed in a human stromal cell line by reverse transcription-polymerase chain reaction (RT-PCR).
Biochim Biophys Acta. Jun 30;1222(2):141-6.(1994)
Ohtsuki T, Hatake K, Suzu S, Harigaya K, Miura Y, Motoyoshi K.
Alteration of the proteoglycan form of macrophage colony-stimulating factor produced by a human stromal line stimulated by tumor necrosis factor-alpha.
Exp Hematol. Apr;22(4):366-9.(1994)
Hojo H, Yaguchi M, Nagasu M, Aizawa S, Nakano M, Harigaya K, Handa H, Toyama K.
Establishment of a human thymic stromal cell line (R-3-4) and its adhesive capacity with T cells in vitro.
Hematol Pathol. 8(4):177-85.(1994)
Harada H., Kondo T., Ogawa S., Tamura T., Kitagawa M., Tanaka N., Lamphier M.S., Hirai H. and Taniguchi T.
Accelerated exon skipping of IRF-1 and mRNA in human myelodysplasia/leukemia; a possible mechanism of tumor supressor inactivation.
Oncogene. 9;3313-3320.(1994)
Kimura T., Nakayama K., Penninger J., Kitagawa M., Harada H., Matsuyama T., Tanaka N., Kamijo T., Vilcek J., Mak T.W. and Taniguchi T.
Involvement of the IRF-1 transcription factor in antiviral responses to interferons.
Science. 264:1921-1924.(1994)
Tanaka N., Ishihara M., Kitagawa M., Harada H., Kimura T., Matsuyama T. Lamphier M.S., Aizawa S., Mak T.W. and Taniguchi T.
Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1.
Cell. 77:829-839.
Uemura N, Ozawa K, Takahashi K, Tojo A, Tani K, Harigaya K, Suzu S, Motoyoshi K, Matsuda H, Yagita H, et al.
Binding of membrane-anchored macrophage colony-stimulating factor (M-CSF) to its receptor mediates specific adhesion between stromal cells and M-CSF receptor-bearing hematopoietic cells.
Blood. Nov1;82(9):2634-40.(1993)
Kito M, Moriya H, Mikata A, Harigaya K, Takenouchi T, Takada N, Tatezaki S, Umeda T.
Establishment of a cell line from a human giant cell tumor of bone.
Clin Orthop. Sep;(294):353-60(1993)
Takahashi S, Uchimaru K, Harigaya K, Asano S, Yamashita T.
Tumor necrosis factor and interleukin-1 induce activin A gene expression in a human bone marrow stromal cell line.
Biochem Biophys Res Commun. Oct15;188(1):310-7.(1992)
Kitagawa M., Harada H., Tanaka N., Yamamoto H., Harada K., Ishihara M. and Taniguchi T.
Anti-oncogenic and oncogenic potentials of interferon regulatory factors 1 and 2.
J. Interferon Res. 13:S95.(1993)
Akasaka Y, Fujimoto J, Harigaya K, Enomoto Y, Watanabe Y, Hata J.
Monoclonal antibody against bone marrow stromal cells researching its production and characterization.
Acta Pathol Japan. Jul;41(7):499-506.(1991)
Itami M, Takenouchi T, Tamaru J, Harigaya K, Mikata A.
Expression of functional molecules in non-Hodgkin's lymphoma. Correlation with bone marrow involvement and serum LDH value.
Acta Pathol Japan. Apr;41(4):277-85.(1991)
Umezawa A, Tachibana K, Harigaya K, Kusakari S, Kato S, Watanabe Y, Takano T.
Colony-stimulating factor 1 expression is down-regulated during the adipocyte differentiation of H-1/A marrow stromal cells and induced by cachectin/tumor necrosis factor.
Mol Cell Biol. Feb;11(2):920-7.(1991)
Kitagawa M., Takasawa S. Kikuchi N. Itoh T., Teraoka H. Yamamoto H. and Okamoto H.
Rig encodes ribosomal protein S15. The primary structure of mammalian ribosomal protein S15.
FEBS Lett. 283:210-214.(1991)
Nomori H, Ishihara T, Torikata C, Harigaya K, Mikata A.
A case of massive true thymic hyperplasia with non-Hodgkin's lymphoma.
Chest. Nov;98(5):1304-5.(1990)
Umezawa A, Harigaya K, Abe H, Watanabe Y.
Gap -junctional communication of bone marrow stromal cells resistant to irradiation in vitro.
Exp Hematol. Oct;18(9):1002-7.(1990)
Hayakawa T, Yamashita K, Kishi J, Harigaya K.
Tissue inhibitor of metalloproteinases from human bone marrow stromal cell line KM 102 had erythroid-potentiating activity, suggesting that its possibly bifunctional role in the hematopoietic microenvironment.
FEBS Lett. Jul 30;268(1):125-8.(1990)
Santucci MA, FitzGerald TJ, Harigaya K, Woda B, Sakakeeny MA, Anklesaria P, Kase K, Holland CA, Greenberger JS.
Gamma-irradiation response of cocultivated bone marrow stromal cell lines of differing intrinsic radiosensitivity.
Int J Radiat Oncol Biol Phys. May;18(5):1083-92.(1990)
Holland CA, Chada S, Wright J, Whitney C, Harigaya K, Greenberger JS, Newburger PE.
Differentiation of human hematopoietic cells increases expression of a gene transferred by a retroviral vector.
J Leukoc Biol. Sep;46(3):221-9.(1989)
Ohkawa H, Mikata A, Harigaya K, Ueda R.
Novel functions and cellular interaction of human lymphoid stromal cells with lymphoid cell lines in vitro.
Exp Hematol. Jan;17(1):30-3.(1989)
Holland CA, Rothstein L, Sakakeeny MA, Anklesaria P, Griffin JD, Harigaya K, Newburger PE, Greenberger JS.
Infection of hematopoietic and stromal cells in human continuous bone marrow cultures by a retroviral vector containing the neomycin resistance gene.
Acta Haematol. 82(3):136-43.(1989)
Takasawa S., Inoue C., Shiga K., and Kitagawa M..
Molecular biology of the islets of Langerhans.H.
Okamoto, Eds.,Cambridge University Press, Cambridge. pp 287-299.(1989)
FitzGerald TJ, Santucci MA, Harigaya K, Woda B, McKenna M, Sakakeeny MA, Pierce JH, Kase K, Holland CA, Greenberger JS.
Radiosensitivity of permanent human bone marrow stromal cell lines - effect of dose rate.
Int J Radiat Oncol Biol Phys. Nov;15(5):1153-9.(1988)
Kohama T, Handa H, Harigaya K.
A burst-promoting activity derived from the human bone marrow stromal cell line KM-102 is identical to the granulocyte-macrophage colony-stimulating factor.
Exp Hematol. Aug;16(7):603-8.(1988)
Okamoto H., Yamamoto H., Takasawa S., Inoue C., Terazono K. Shiga K., Kitagawa M..
Molecular mechsnism of degeneration, oncogenesis and regeneration of pancreatic B-cells of islets of Langerbans.In: Frontiers in diabetes research. Lessons from animal diabetes II.E. Shafrir & A.E.
Renoldeds, John Libbey & Co. Ltd., London, Paris. pp 149-157.(1988)
Inoue C., Igarashi K., Kitagawa M., Terasono K., Takasawa S., Obata K., Iwata K., Yamamoto H. and Okamato H.
Expression of the insulinoma gene rig during liver regeneration and in primary cultured hepatocytes.
Biochem. Biophys. Res. Commun. 150:1302-1308.(1988)
Harigaya K.
Fibrocytic bone marrow stromal cells and hematopoiesis.
Nippon Ketsueki Gakkai Zasshi. Dec;50(8):1499-509.(1987)
Ohkawa H, Harigaya K.
Effect of direct cell-to-cell interaction between the KM-102 clonal human marrow stromal cell line and the HL-60 myeloid leukemic cell line on the differentiation and proliferation of the HL-60 line.
Cancer Res. Jun 1;47(11):2879-82.(1987)
Watanabe Y, Enomoto Y, Yamada T, Harigaya K.
Histopathological analysis of cases of megakaryocytic leukemia.
Keio J Med. Jan;36(1):71-3.(1987) `No abstract available
Inoue C., Shiga K., Takasawa S., Kitagawa M., Yamamato H. and Okamoto H.
Evolutionary conservation of the insulinoma gene rig and its possible function.Proc. Natl. Acad.
Sci.USA. 84:6659-6662.(1987)
Harigaya K, Todoroki T, Nakamura M, Watanabe Y.
Conversion to adipocytes of a clonal bone marrow preadipocyte line (H-1/A) and fatty acid composition of the resultant adipocytes.
Proc Soc Exp Biol Med. Apr;181(4):523-8.(1986)
Yoshida K, Toya S, Ohtani M, Okui S, Takenaka N, Harigaya K.
Extraneural metastasis of choriocarcinomatous element in pineal germ-cell tumor. Case report.
J Neurosurg. Sep;63(3):463-6.(1985)
Nakamura M, Harigaya K, Watanabe Y.
Correlation between production of colony-stimulating activity (CSA) and adipose conversion in a murine marrow-derived preadipocyte line (H-1/A).
Proc Soc Exp Biol Med. Jul;179(3):283-7.(1985)
Harigaya K, Handa H.
Generation of functional clonal cell lines from human bone marrow stroma.
Proc Natl Acad Sci USA. May;82(10):3477-80.(1985)
Garnett HM, Harigaya K, Cronkite EP.
Influence of a fibroblastoid cell line derived from murine bone marrow (H-1 cells) on stem cell proliferation.
Proc Soc Exp Biol Med. Jan;175(1):70-3.(1984)
Garnett HM, Cronkite EP, Harigaya K.
Regulation of the colony-stimulating activity produced by a murine marrow-derived cell line (H-1).
Proc Natl Acad Sci USA. Mar;79(5):1545-8.(1982)
Garnett HM, Harigaya K, Cronkite EP.
Characterization of a murine cell-line derived from cultured bone marrow stromal cells.
Stem Cells. 2(1):11-23.(1982)
Harigaya K, Cronkite EP, Miller ME, Shadduck RK.
Murine bone marrow cell line producing colony-stimulating factor.
Proc Natl Acad Sci USA. Nov;78(11):6963-6.(1981)
Harigaya K, Miller ME, Cronkite EP, Drew RT.
The detection of in vivo hematotoxicity of benzene by in vitro liquid bone marrow cultures.
Toxicol Appl Pharmacol. Sep 15;60(2):346-53.(1981)
Harigaya K, Cronkite EP, Miller ME, Moccia G.
Further evidence of the in vivo role of erythropoietin or companion molecules induced by hypoxia on proliferation and continuing differentiation of BFU-e in PCDC.
Blood. Feb;57(2):298-304.(1981)
Harigaya K., Mikata A., Suzuki H., Ohishi T., Kageyama K., Minato K., Shimoyama M.
Mg2+-dependent adenosine triphosphatase as an enzyme histochemical marker for the lymphomas of B-cell origin.
Am J Pathol. 97:359-380.(1979)
Mikata A., Harigaya K., Suzuki H., Ohishi T., Tsutsumi Y., Suzuki S., Watanabe S., Kageyama K.
Enzyme histochemistry of non-Hodgkin's lymphomas.
Acta Pathol Japan. 29:739-753.(1979)
Harigaya K., Watanabe S., Watanabe Y., Kageyama K., and Nakazawa K.
Multiple bone marrow necrosis and disseminated intravascular coagulation
Arch. Pathol. Lab. Med. 101:652-654. (1977)
Harigaya K.
Enzyme - histochemical characteristics of non-Hodgkin's lymphomas.
Acta Pathol Japan. 27:345-355.(1977)
Books
Hematopoietic Stem Cells
Characterization, Proliferation, Regulation.(Ed Killmann, SV.-AA.)
Regulation of hemopoiesis: inhibitor and stimulator produced by murine bone marrow stromal cell line (H-1)
(E.P. Muller-Berat, C.N.Cronkite, E. P. Miller, M. E. Garnett, H. M. and Harigaya K)
Munksgaad, Copenhagen. (1983)
Experimental Hematology Today
(ed Baum S.J., Ledney G.D., Thierfelder S.
Production of colony-stimulating factor by murine bone marrow cell line derived from the Dexter adherent layer and other properties of this cell line
(Cronkite E. P., Harigaya K., Garnett H. M., Miller M. E., Honikel L and Shadduck R. K.)
pp11-18, S. Karger, Basel. (1982)
Excepta Medica International Congress Series No.415
Topics in Hematology
Enzyme histochemical and ultrastructural studies of non-Hodgkin's lymphomas
(Mikata A., Harigaya K., Ohishi T., Suzuki H. and Kageyama K.)
Pages 344-347, Excepta Medica, Amsterdam. (1976)
Meetings
Mastushita K, Tominaga T, Higashi M, Shioya A, Matsubara H, Harigaya K, Nomura F, Ochiai T, Libutti D, Levens D.
An essential role of alternative splicing of c-myc suppressor FIR in carcinogenesis.
96th Annual Meeting American Association for Cancer Research.
Anaheim, CA. Arpril 16-20 (2005)
Harigaya K, Tsuchiya H, Higashi M, Kitagawa M.
CD44 regulates the cell motility by coordinated RhoA-dependent Rac1 activation and induces an enhanced cell migration for Mol Boiol Cell 15: 66a, 245.
44th Annual Meeting The American Society for Cell Biology.
Washington DC. Dec 4-8th (2004)
Higashi M, Tsuchiya H, Kitagawa M, Kurokawa K, Matsuda M, Kumagai S, Miyoshi H, Harigaya K
CD44 regualtes the initial steps of cell migration throught its microtuble-dependent mobillization to lamellipodia via activation of Rho GTPases for Molecular Cell Biology of Lipid Domains.
Keystone Symposia. Vancouver, Canada. March 26-31 (2004)
Kasagawa T, Kishi H, Higashi M, Kitagawa M, Harigaya K
Association of RanBPM to CD44 ERM-bindign domain is necessary to CD44-dependent Cell Motility for Cell Migration and Invasion.
218. Keystone Symposia. Breckenridge, Colorado. Jan 18-23 (2003)