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田中宏一

Tanaka Hirokazu国際医療福祉大学教授 医学博士

所属

国際医療福祉大学
千葉大学医学部附属病院 周産期母性科

学歴・職歴

千葉大学大学院医学研究科

専門分野

妊娠,分娩管理

研究課題

胎盤形成におけるEVTの役割

キーワード

G protein-coupled receptor (GPCR)

研究可能テーマ

Cell signaling

研究業績

主な論文

  1. Irukayama-Tomobe Y, Tanaka H, Yokomizo T, Hashidate-Yoshida T, Yanagisawa M, Sakurai T.  Aromatic D-amino acids act as chemoattractant factors for human leukocytes through a G protein-coupled receptor, GPR109B.  Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3930-4.
  2. Kitamura Y, Tanaka H, Motoike T, Ishii M, Williams SC, Yanagisawa M, Sakurai T. Distribution of neuropeptide W immunoreactivity and mRNA in adult rat brain. Brain Res. 2006 Jun 6;1093(1):123-34.
  3. Hida T, Takahashi E, Shikata K, Hirohashi T, Sawai T, Seiki T, Tanaka H, Kawai T, Ito O, Arai T, Yokoi A, Hirakawa T, Ogura H, Nagasu T, Miyamoto N, Kuromitsu J.  Chronic intracerebroventricular administration of relaxin-3 increases body weight in rats. J Recept Signal Transduct Res. 2006;26(3):147-58.
  4. Thompson MD, Comings DE, Abu-Ghazalah R, Jereseh Y, Lin L, Wade J, Sakurai T, Tokita S, Yoshida T, Tanaka H, Yanagisawa M, Burnham WM, Moldofsky H. Variants of the orexin2/hcrt2 receptor gene identified in patients with excessive daytime sleepiness and patients with Tourette's syndrome comorbidity. Am J Med Genet B Neuropsychiatr Genet. 2004 Aug 15;129(1):69-75.
  5. Tanaka H, Yoshida T, Miyamoto N, Motoike T, Kurosu H, Shibata K, Yamanaka A, Williams SC, Richardson JA, Tsujino N, Garry MG, Lerner MR, King DS, O'Dowd BF, Sakurai T, Yanagisawa M. Characterization of a family of endogenous neuropeptide ligands for the G protein-coupled receptors GPR7 and GPR8. Proc Natl Acad Sci U S A. 2003 May 13;100(10):6251-6.
  6. Xiong Y, Tanaka H, Richardson JA, Williams SC, Slaughter CA, Nakamura M, Chen JL, Yanagisawa M. Endothelin-1 stimulates leptin production in adipocytes. J Biol Chem. 2001 Jul 27;276(30):28471-7.
  7. Kane JK, Tanaka H, Parker SL, Yanagisawa M, Li MD. Sensitivity of orexin-A binding to phospholipase C inhibitors, neuropeptide Y, and secretin. Biochem Biophys Res Commun. 2000 Jun 16;272(3):959-65.
  8. Mitsuhashi A, Tanaka H, Tanaka N, Sugita M, Shirasawa H, Tokita H, Eda H, Sekiya S. Establishment and characterization of a new HPV-negative squamous cell carcinoma cell line (Yumoto) from the human uterine cervix. Gynecol Oncol. 1998 Sep;70(3):339-47.
  9. Tanaka H, Moroi K, Iwai J, Takahashi H, Ohnuma N, Hori S, Takimoto M, Nishiyama M, Masaki T, Yanagisawa M, Sekiya S, Kimura S. Novel mutations of the endothelin B receptor gene in patients with Hirschsprung's disease and their characterization. J Biol Chem. 1998 May 1;273(18):11378-83.
  10. Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richarson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell. 1998 Feb 20;92(4):573-85.
  11. Mizuguchi T, Nishiyama M, Moroi K, Tanaka H, Saito T, Masuda Y, Masaki T, de Wit D, Yanagisawa M, Kimura S. Analysis of two pharmacologically predicted endothelin B receptor subtypes by using the endothelin B receptor gene knockout mouse. Br J Pharmacol. 1997 Apr;120(8):1427-30.

所属学会

日本産婦人科学会
日本周産期新生児医学会
日本人類遺伝学会

招待講演等

第111回日本薬理学会関東部会(2004)シンポジウム

ひとこと

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