業績

 【原著論文】

 

2019 

Kawakami E, Tabata J, Yanaihara N, Ishikawa T, Koseki K, Iida Y, Saito M, Komazaki H, Shapiro JS, Goto C, Akiyama Y, Saito R, Saito M, Takano H, Yamada K, Okamoto A;Application of Artificial Intelligence for Preoperative Diagnostic and Prognostic Prediction in Epithelial Ovarian Cancer Based on Blood Biomarkers.Clinical cancer research : an official journal of the American Association for Cancer Research 2019

Ono R, Watanabe T, Kawakami E, Iwasaki M, Tomizawa-Murasawa M, Matsuda M, Najima Y, Takagi S, Fujiki S, Sato R, Mochizuki Y, Yoshida H, Sato K, Yabe H, Kato S, Saito Y, Taniguchi S, Shultz LD, Ohara O, Amagai M, Koseki H, Ishikawa F;Co-activation of macrophages and T cells contribute to chronic GVHD in human IL-6 transgenic humanised mouse model.EBioMedicine 2019

2018 

Ise W, Fujii K, Shiroguchi K, Ito A, Kometani K, Takeda K, Kawakami E, Yamashita K, Suzuki K, Okada T, Kurosaki T., T Follicular Helper Cell-Germinal Center B Cell Interaction Strength Regulates Entry into Plasma Cell or Recycling Germinal Center Cell Fate.,Immunity, 48, 702-715, e4, 2018

Fujimoto H, Saito Y, Ohuchida K, Kawakami E, Fujiki S, Watanabe T, Ono R, Kaneko A, Takagi S, Najima Y, Hijikata A, Cui L, Ueki T, Oda Y, Hori S, Ohara O, Nakamura M, Saito T, Ishikawa F., Deregulated Mucosal Immune Surveillance through Gut-Associated Regulatory T Cells and PD-1+ T Cells in Human Colorectal Cancer., The Journal of Immunology, 200, 3291-3303, 2018

Miyai T, Takano J, Endo TA, Kawakami E, Agata Y, Motomura Y, Kubo M, Kashima Y, Suzuki Y, Kawamoto H, Ikawa T., Three-step transcriptional priming that drives the commitment of multipotent progenitors toward B cells., Genes Dev., 32, 112-126, 2018

Kochi Y, Kamatani Y, Kondo Y, Suzuki A, Kawakami E, Hiwa R, Momozawa Y, Fujimoto M, Jinnin M, Tanaka Y, Kanda T, Cooper RG, Chinoy H, Rothwell S, Lamb JA, Vencovský J, Mann H, Ohmura K, Myouzen K, Ishigaki K, Nakashima R, Hosono Y, Tsuboi H, Kawasumi H, Iwasaki Y, Kajiyama H, Horita T, Ogawa-Momohara M, Takamura A, Tsunoda S, Shimizu J, Fujio K, Amano H, Mimori A, Kawakami A, Umehara H, Takeuchi T, Sano H, Muro Y, Atsumi T, Mimura T, Kawaguchi Y, Mimori T, Takahashi A, Kubo M, Kohsaka H, Sumida T, Yamamoto K., Splicing variant of WDFY4 augments MDA5 signalling and the risk of clinically amyopathic dermatomyositis., Annals of the rheumatic diseases, annrheumdis-2017-212149, 2018  

2017 

Kawakami E, Adachi N, Senda T, Horikoshi M., Leading role of TBP in the Establishment of Complexity in Eukaryotic Transcription Initiation Systems., Cell Reports, 21, 3941-3956, 2017

Tenno M, Shiroguchi K, Muroi S, Kawakami E, Koseki K, Kryukov K, Imanishi T, Ginhoux F, Taniuchi I., Cbfβ2 deficiency preserves Langerhans cell precursors by lack of selective TGFβ receptor signaling., J. Exp. Med., 214, 2933-2946, 2017

Hayatsu N, Miyao T, Tachibana M, Murakami R, Kimura A, Kato T, Kawakami E, Endo TA, Setoguchi R, Watarai H, Nishikawa T, Yasuda T, Yoshida H, Hori S., Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells., Immunity,47, 268-283.e9, 2017

Kiso M, Iwatsuki-Horimoto K, Yamayoshi S, Uraki R, Ito M, Nakajima N, Yamada S, Imai M, Kawakami E, Tomita Y, Fukuyama S, Itoh Y, Ogasawara K, Lopes TJS, Watanabe T, Moncla LH, Hasegawa H, Friedrich TC, Neumann G, Kawaoka Y., Emergence of oseltamivir-resistant H7N9 influenza viruses in immunosuppressed cynomolgus macaques., The Journal of infectious diseases,216, 582-593, 2017    

2016 

Kawakami E*, Nakaoka S, Ohta T, Kitano H., Weighted enrichment method for prediction of transcription regulators from transcriptome and global chromatin immunoprecipitation data., Nucleic Acids Res., 44, 5010-21, 2016(*Corresponding author) 

Okada Y, Muramatsu T, Suita N, Kanai M, Kawakami E, Valentina Iotchkova, Nicole Soranzo, Inazawa J, Tanaka T., Significant impact of miRNA–target gene networks on genetics of human complex traits., Scientific reports,6, 22223, 2016

Kawakami E, Singh VK, Matsubara K, Ishii T, Matsuoka Y, Hase T, Kulkarni P, Siddiqui K, Kodilkar J, Danve N, Subramanian I, Katoh M, Shimizu-Yoshida Y, Ghosh S, Jere A, Kitano H., Network analyses based on comprehensive molecular interaction maps reveal robust control structures in yeast stress response pathways., npj Syst. Biol. App., 2, 15018, 2016

2015 

Picazarri K, Nakada-Tsukui K, Tsuboi K, Miyamoto E, Watanabe N, Kawakami E, Nozaki T., Atg8 is involved in endosomal and phagosomal acidification in the parasitic protist Entamoeba histolytica., Cell. Microbiol., 17, 1510-22, 2015

Shoemaker JE, Fukuyama S, Eisfeld AJ, Zhao D, Kawakami E, Sakabe S, Maemura T, Gorai T, Katsura H, Muramoto Y, Watanabe S, Watanabe T, Fuji K, Matsuoka Y, Kitano H, Kawaoka Y., An Ultrasensitive Mechanism Regulates Influenza Virus-Induced Inflammation., PLoS Pathog.,11, e1004856, 2015

2014

Watanabe T, Kawakami E, Shoemaker JE, Lopes TJ, Matsuoka Y, Tomita Y, Kozuka-Hata H, Gorai T, Kuwahara T, Takeda E, Nagata A, Takano R, Kiso M, Yamashita M, Sakai-Tagawa Y, Katsura H, Nonaka N, Fujii H, Fujii K, Sugita Y, Noda T, Goto H, Fukuyama S, Watanabe S, Neumann G, Oyama M, Kitano H, Kawaoka Y., Influenza virus-host interactome screen as a platform for antiviral drug development., Cell Host Microbe, 16, 795-805, 2014

Muramoto Y, Shoemaker JE, Le MQ, Itoh Y, Tamura D, Sakai-Tagawa Y, Imai H, Uraki R, Takano R, Kawakami E, Ito M, Okamoto K, Ishigaki H, Mimuro H, Sasakawa C, Matsuoka Y, Noda T, Fukuyama S, Ogasawara K, Kitano H, Kawaoka Y., Disease severity is associated with differential gene expression at the early and late phases of infection in nonhuman primates infected with different H5N1 highly pathogenic avian influenza viruses., J. Virol., 88, 8981-97, 2014 

2013 

Watanabe T, Kiso M, Fukuyama S, Nakajima N, Imai M, Yamada S, Murakami S, Yamayoshi S, Iwatsuki-Horimoto K, Sakoda Y, Takashita E, McBride R, Noda T, Hatta M, Imai H, Zhao D, Kishida N, Shirakura M, de Vries RP, Shichinohe S, Okamatsu M, Tamura T, Tomita Y, Fujimoto N, Goto K, Katsura H, Kawakami E, Ishikawa I, Watanabe S, Ito M, Sakai-Tagawa Y, Sugita Y, Uraki R, Yamaji R, Eisfeld AJ, Zhong G, Fan S, Ping J, Maher EA, Hanson A, Uchida Y, Saito T, Ozawa M, Neumann G, Kida H, Odagiri T, Paulson JC, Hasegawa H, Tashiro M, Kawaoka Y., Characterization of H7N9 influenza A viruses isolated from humans., Nature, 501, 551-5, 2013

Muramoto Y, Noda T, Kawakami E, Akkina R, Kawaoka Y., Identification of novel influenza A virus proteins translated from PA mRNA., J. Virol.,87, 2455-62, 2013

2012 

Watanabe T, Imai M, Watanabe S, Shinya K, Hatta M, Li C, Neumann G, Ozawa M,Hanson A, Zhong G, Fukuyama S, Kawakami E, Simmons HA, Schenkman D, Brunner K, Capuano SV 3rd, Weinfurter JT, Kilander A, Dudman SG, Suresh M, Hungnes O, Friedrich TC, Kawaoka Y*., Characterization in vitro and in vivo of pandemic (H1N1) 2009 influenza viruses isolated from patients., J. Virol.86, 9361-9368, 2012

Imai M, Watanabe T, Hatta M, Das SC, Ozawa M, Shinya K, Zhong G, Hanson A, Katsura H, Watanabe S, Li C, Kawakami E, Yamada S, Kiso M, Suzuki Y, Maher EA, Neumann G, Kawaoka Y*., Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets., Nature,486, 420-428, 2012

Noda T, Sugita Y, Aoyama K, Hirase A, Kawakami E, Miyazawa A, Sagara H, Kawaoka Y*., Three-dimensional analysis of ribonucleoprotein complexes in influenza A virus., Nat. Commun., 3, 639, 2012 

2011

Watanabe T, Shinya K, Watanabe S, Imai M, Hatta M, Li C, Wolter BF, Neumann G, Hanson A, Ozawa M, Yamada S, Imai H, Sakabe S, Takano R, Iwatsuki-Horimoto K, Kiso M, Ito M, Fukuyama S, Kawakami E, Gorai T, Simmons HA, Schenkman D, Brunner K, Capuano SV 3rd, Weinfurter JT, Nishio W, Maniwa Y, Igarashi T, Makino A, Travanty EA, Wang J, Kilander A, Dudman SG, Suresh M, Mason RJ, Hungnes O, Friedrich TC, Kawaoka Y*., Avian-type receptor-binding ability can increase influenza virus pathogenicity in macaques., J. Virol., 85, 13195-13203, 2011

Eisfeld AJ, Kawakami E, Watanabe T, Neumann G, Kawaoka Y*., RAB11A is essential for transport of the influenza virus genome to the plasma membrane., J. Virol., 85, 6117-6126, 2011

Iwatsuki-Horimoto K, Horimoto T, Tamura D, Kiso M, Kawakami E, Hatakeyama S,Ebihara Y, Koibuchi T, Fujii T, Takahashi K, Shimojima M, Sakai-Tagawa Y, Ito M, Sakabe S, Iwasa A, Takahashi K, Ishii T, Gorai T, Tsuji K, Iwamoto A, Kawaoka Y*., Seroprevalence of pandemic 2009 (H1N1) influenza A virus among schoolchildren and their parents in Tokyo, Japan., Clin. Vaccine Immunol., 18, 860-866, 2011

Kawakami E, Watanabe T, Fujii K, Goto H, Watanabe S, Noda T, Kawaoka Y*., Strand-specific real-time RT-PCR for distinguishing influenza vRNA, cRNA, and mRNA., J. Virol. Methods,173, 1-6, 2011

Tamura D, Sugaya N, Ozawa M, Takano R, Ichikawa M, Yamazaki M, Kawakami C, Shimizu H, Uehara R, Kiso M, Kawakami E, Mitamura K, Kawaoka Y*., Frequency of drug-resistant viruses and virus shedding in pediatric influenza patients treated with neuraminidase inhibitors., Clin. Infect. Dis., 52, 432-437, 2011

Akarsu H, Iwatsuki-Horimoto K, Noda T, Kawakami E, Katsura H, Baudin F, Horimoto T, Kawaoka Y., Structure-based design of NS2 mutants for attenuated influenza A virus vaccines., Virus res., 155, 240-248, 2011

 

 
 
 
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