【原著論文】
２０１９
Kawakami E, Tabata J, Yanaihara N, Ishikawa T, Koseki K, Iida Y, Saito M, Komazaki H, Shapiro JS, Goto C, Akiyama Y, Saito R, Saito M, Takano H, Yamada K, Okamoto A；Application of Artificial Intelligence for Preoperative Diagnostic and Prognostic Prediction in Epithelial Ovarian Cancer Based on Blood Biomarkers.Clinical cancer research : an official journal of the American Association for Cancer Research 2019
Ono R, Watanabe T, Kawakami E, Iwasaki M, Tomizawa-Murasawa M, Matsuda M, Najima Y, Takagi S, Fujiki S, Sato R, Mochizuki Y, Yoshida H, Sato K, Yabe H, Kato S, Saito Y, Taniguchi S, Shultz LD, Ohara O, Amagai M, Koseki H, Ishikawa F；Co-activation of macrophages and T cells contribute to chronic GVHD in human IL-6 transgenic humanised mouse model.EBioMedicine 2019
２０１８
Ise W, Fujii K, Shiroguchi K, Ito A, Kometani K, Takeda K, Kawakami E, Yamashita K, Suzuki K, Okada T, Kurosaki T., T Follicular Helper Cell-Germinal Center B Cell Interaction Strength Regulates Entry into Plasma Cell or Recycling Germinal Center Cell Fate.,Immunity, 48, 702-715, e4, 2018
Fujimoto H, Saito Y, Ohuchida K, Kawakami E, Fujiki S, Watanabe T, Ono R, Kaneko A, Takagi S, Najima Y, Hijikata A, Cui L, Ueki T, Oda Y, Hori S, Ohara O, Nakamura M, Saito T, Ishikawa F., Deregulated Mucosal Immune Surveillance through Gut-Associated Regulatory T Cells and PD-1+ T Cells in Human Colorectal Cancer., The Journal of Immunology, 200, 3291-3303, 2018
Miyai T, Takano J, Endo TA, Kawakami E, Agata Y, Motomura Y, Kubo M, Kashima Y, Suzuki Y, Kawamoto H, Ikawa T., Three-step transcriptional priming that drives the commitment of multipotent progenitors toward B cells., Genes Dev., 32, 112-126, 2018
Kochi Y, Kamatani Y, Kondo Y, Suzuki A, Kawakami E, Hiwa R, Momozawa Y, Fujimoto M, Jinnin M, Tanaka Y, Kanda T, Cooper RG, Chinoy H, Rothwell S, Lamb JA, Vencovský J, Mann H, Ohmura K, Myouzen K, Ishigaki K, Nakashima R, Hosono Y, Tsuboi H, Kawasumi H, Iwasaki Y, Kajiyama H, Horita T, Ogawa-Momohara M, Takamura A, Tsunoda S, Shimizu J, Fujio K, Amano H, Mimori A, Kawakami A, Umehara H, Takeuchi T, Sano H, Muro Y, Atsumi T, Mimura T, Kawaguchi Y, Mimori T, Takahashi A, Kubo M, Kohsaka H, Sumida T, Yamamoto K., Splicing variant of WDFY4 augments MDA5 signalling and the risk of clinically amyopathic dermatomyositis., Annals of the rheumatic diseases, annrheumdis-2017-212149, 2018
２０１７
Kawakami E, Adachi N, Senda T, Horikoshi M., Leading role of TBP in the Establishment of Complexity in Eukaryotic Transcription Initiation Systems., Cell Reports, 21, 3941-3956, 2017
Tenno M, Shiroguchi K, Muroi S, Kawakami E, Koseki K, Kryukov K, Imanishi T, Ginhoux F, Taniuchi I., Cbfβ2 deficiency preserves Langerhans cell precursors by lack of selective TGFβ receptor signaling., J. Exp. Med., 214, 2933-2946, 2017
Hayatsu N, Miyao T, Tachibana M, Murakami R, Kimura A, Kato T, Kawakami E, Endo TA, Setoguchi R, Watarai H, Nishikawa T, Yasuda T, Yoshida H, Hori S., Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells., Immunity,47, 268-283.e9, 2017
Kiso M, Iwatsuki-Horimoto K, Yamayoshi S, Uraki R, Ito M, Nakajima N, Yamada S, Imai M, Kawakami E, Tomita Y, Fukuyama S, Itoh Y, Ogasawara K, Lopes TJS, Watanabe T, Moncla LH, Hasegawa H, Friedrich TC, Neumann G, Kawaoka Y., Emergence of oseltamivir-resistant H7N9 influenza viruses in immunosuppressed cynomolgus macaques., The Journal of infectious diseases,216, 582-593, 2017
２０１６
Kawakami E*, Nakaoka S, Ohta T, Kitano H., Weighted enrichment method for prediction of transcription regulators from transcriptome and global chromatin immunoprecipitation data., Nucleic Acids Res., 44, 5010-21, 2016(*Corresponding author)
Okada Y, Muramatsu T, Suita N, Kanai M, Kawakami E, Valentina Iotchkova, Nicole Soranzo, Inazawa J, Tanaka T., Significant impact of miRNA–target gene networks on genetics of human complex traits., Scientific reports,6, 22223, 2016
Kawakami E, Singh VK, Matsubara K, Ishii T, Matsuoka Y, Hase T, Kulkarni P, Siddiqui K, Kodilkar J, Danve N, Subramanian I, Katoh M, Shimizu-Yoshida Y, Ghosh S, Jere A, Kitano H., Network analyses based on comprehensive molecular interaction maps reveal robust control structures in yeast stress response pathways., npj Syst. Biol. App., 2, 15018, 2016
２０１５
Picazarri K, Nakada-Tsukui K, Tsuboi K, Miyamoto E, Watanabe N, Kawakami E, Nozaki T., Atg8 is involved in endosomal and phagosomal acidification in the parasitic protist Entamoeba histolytica., Cell. Microbiol., 17, 1510-22, 2015
Shoemaker JE, Fukuyama S, Eisfeld AJ, Zhao D, Kawakami E, Sakabe S, Maemura T, Gorai T, Katsura H, Muramoto Y, Watanabe S, Watanabe T, Fuji K, Matsuoka Y, Kitano H, Kawaoka Y., An Ultrasensitive Mechanism Regulates Influenza Virus-Induced Inflammation., PLoS Pathog.,11, e1004856, 2015
２０１４
Watanabe T, Kawakami E, Shoemaker JE, Lopes TJ, Matsuoka Y, Tomita Y, Kozuka-Hata H, Gorai T, Kuwahara T, Takeda E, Nagata A, Takano R, Kiso M, Yamashita M, Sakai-Tagawa Y, Katsura H, Nonaka N, Fujii H, Fujii K, Sugita Y, Noda T, Goto H, Fukuyama S, Watanabe S, Neumann G, Oyama M, Kitano H, Kawaoka Y., Influenza virus-host interactome screen as a platform for antiviral drug development., Cell Host Microbe, 16, 795-805, 2014
Muramoto Y, Shoemaker JE, Le MQ, Itoh Y, Tamura D, Sakai-Tagawa Y, Imai H, Uraki R, Takano R, Kawakami E, Ito M, Okamoto K, Ishigaki H, Mimuro H, Sasakawa C, Matsuoka Y, Noda T, Fukuyama S, Ogasawara K, Kitano H, Kawaoka Y., Disease severity is associated with differential gene expression at the early and late phases of infection in nonhuman primates infected with different H5N1 highly pathogenic avian influenza viruses., J. Virol., 88, 8981-97, 2014
２０１３
Watanabe T, Kiso M, Fukuyama S, Nakajima N, Imai M, Yamada S, Murakami S, Yamayoshi S, Iwatsuki-Horimoto K, Sakoda Y, Takashita E, McBride R, Noda T, Hatta M, Imai H, Zhao D, Kishida N, Shirakura M, de Vries RP, Shichinohe S, Okamatsu M, Tamura T, Tomita Y, Fujimoto N, Goto K, Katsura H, Kawakami E, Ishikawa I, Watanabe S, Ito M, Sakai-Tagawa Y, Sugita Y, Uraki R, Yamaji R, Eisfeld AJ, Zhong G, Fan S, Ping J, Maher EA, Hanson A, Uchida Y, Saito T, Ozawa M, Neumann G, Kida H, Odagiri T, Paulson JC, Hasegawa H, Tashiro M, Kawaoka Y., Characterization of H7N9 influenza A viruses isolated from humans., Nature, 501, 551-5, 2013
Muramoto Y, Noda T, Kawakami E, Akkina R, Kawaoka Y., Identification of novel influenza A virus proteins translated from PA mRNA., J. Virol.,87, 2455-62, 2013
２０１２
Watanabe T, Imai M, Watanabe S, Shinya K, Hatta M, Li C, Neumann G, Ozawa M,Hanson A, Zhong G, Fukuyama S, Kawakami E, Simmons HA, Schenkman D, Brunner K, Capuano SV 3rd, Weinfurter JT, Kilander A, Dudman SG, Suresh M, Hungnes O, Friedrich TC, Kawaoka Y*., Characterization in vitro and in vivo of pandemic (H1N1) 2009 influenza viruses isolated from patients., J. Virol., 86, 9361-9368, 2012
Imai M, Watanabe T, Hatta M, Das SC, Ozawa M, Shinya K, Zhong G, Hanson A, Katsura H, Watanabe S, Li C, Kawakami E, Yamada S, Kiso M, Suzuki Y, Maher EA, Neumann G, Kawaoka Y*., Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets., Nature,486, 420-428, 2012
Noda T, Sugita Y, Aoyama K, Hirase A, Kawakami E, Miyazawa A, Sagara H, Kawaoka Y*., Three-dimensional analysis of ribonucleoprotein complexes in influenza A virus., Nat. Commun., 3, 639, 2012
２０１１
Watanabe T, Shinya K, Watanabe S, Imai M, Hatta M, Li C, Wolter BF, Neumann G, Hanson A, Ozawa M, Yamada S, Imai H, Sakabe S, Takano R, Iwatsuki-Horimoto K, Kiso M, Ito M, Fukuyama S, Kawakami E, Gorai T, Simmons HA, Schenkman D, Brunner K, Capuano SV 3rd, Weinfurter JT, Nishio W, Maniwa Y, Igarashi T, Makino A, Travanty EA, Wang J, Kilander A, Dudman SG, Suresh M, Mason RJ, Hungnes O, Friedrich TC, Kawaoka Y*., Avian-type receptor-binding ability can increase influenza virus pathogenicity in macaques., J. Virol., 85, 13195-13203, 2011
Eisfeld AJ, Kawakami E, Watanabe T, Neumann G, Kawaoka Y*., RAB11A is essential for transport of the influenza virus genome to the plasma membrane., J. Virol., 85, 6117-6126, 2011
Iwatsuki-Horimoto K, Horimoto T, Tamura D, Kiso M, Kawakami E, Hatakeyama S,Ebihara Y, Koibuchi T, Fujii T, Takahashi K, Shimojima M, Sakai-Tagawa Y, Ito M, Sakabe S, Iwasa A, Takahashi K, Ishii T, Gorai T, Tsuji K, Iwamoto A, Kawaoka Y*., Seroprevalence of pandemic 2009 (H1N1) influenza A virus among schoolchildren and their parents in Tokyo, Japan., Clin. Vaccine Immunol., 18, 860-866, 2011
Kawakami E, Watanabe T, Fujii K, Goto H, Watanabe S, Noda T, Kawaoka Y*., Strand-specific real-time RT-PCR for distinguishing influenza vRNA, cRNA, and mRNA., J. Virol. Methods,173, 1-6, 2011
Tamura D, Sugaya N, Ozawa M, Takano R, Ichikawa M, Yamazaki M, Kawakami C, Shimizu H, Uehara R, Kiso M, Kawakami E, Mitamura K, Kawaoka Y*., Frequency of drug-resistant viruses and virus shedding in pediatric influenza patients treated with neuraminidase inhibitors., Clin. Infect. Dis., 52, 432-437, 2011
Akarsu H, Iwatsuki-Horimoto K, Noda T, Kawakami E, Katsura H, Baudin F, Horimoto T, Kawaoka Y., Structure-based design of NS2 mutants for attenuated influenza A virus vaccines., Virus res., 155, 240-248, 2011
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