研究業績

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研究業績 2021年-2023年

  • 2023年
  • 2022年
  • 2021年

2023年業績

英文

1. Watanabe Y, Yamaguchi T, Nagayama D,Tanaka S, Sasaki A, Naitoh T, Matsubara H, Yokote K, Okazumi S, Ugi S, Yamamoto H, Ohta M, Ishigaki Y, Kasama K, Seki Y, Tsujino M, Shirai K, Miyazaki Y, Masaki T, Saiki A, Tatsuno I. Factors associated with relapse of type 2 diabetes mellitus after laparoscopic sleeve gastrectomy in Japanese subjects: a subgroup analysis of J-SMART study. Obes Facts. 2023.16(2):119-130.
2. Tsujita K, Yokote K, Ako J, Tanigawa R, Tajima S, Suganami H, K-Clinical Study Group. Efficacy and Safety of Pitavastatin/Ezetimibe Fixed-Dose Combination vs. Pitavastatin: Phase III, Double-Blind, Randomized Controlled Trial. J Atheroscler Thromb. 2023. 30(11):1580-1600.
3. Kinoshita D, Kato H, Kaneko H, Ishikawa T, Teramoto N, Tsukagoshi A, Maeda Y, Minamizuka T, Hayashi A, Shoji M, Sawada D, Funayama S, Koshizaka M, Ogata H, Kubota Y, Mitsukawa N, Takemoto M, Yokote K, Maezawa Y. Case of Werner syndrome with significant improvement of refractory skin ulcer despite fibroblast cellular senescence. Geriatr Gerontol Int. 2023 Mar;23(3):239-241.
4. Shibamiya A, Miyamoto-Nagai Y, Koide S, Oshima M, Rizq O, Aoyama K, Nakajima Y-Takagi, Kato R, Kayamori K, Isshiki Y, Oshima-Hasegawa N, Muto T, Tsukamoto S, Takeda Y, Koyama-Nasu R, Chiba T, Honda H, Yokote K, Iwama A, Sakaida E, Mimura N. The pathogenetic significance of exhausted T cells in a mouse model of mature B cell neoplasms. Cancer Immunol Immunother. 2023. 72(8):2635-2648.
5. Maeda Y, Koshizaka M, Shoji M, Kaneko H, Kato H, Maezawa Y, Kawashima J, Yoshinaga K, Ishikawa M, Sekiguchi A, Motegi S, Nakagami H, Yamada Y, Tsukamoto S, Taniguchi A, Sugimoto K, Takami Y, Shoda Y, Hashimoto K, Yoshimura T, Kogure A, Suzuki D, Okubo N, Yoshida T, Watanabe K, Kuzuya M, Takemoto M, Oshima J, Yokote K. Renal dysfunction, malignant neoplasms, atherosclerotic cardiovascular diseases, and sarcopenia as key outcomes observed in a three-year follow-up study using the Werner Syndrome Registry. Aging (Albany NY). 2023. 1;15(9):3273-3294.
6. Deguchi-Horiuchi H, Suzuki S, Lee EY, Miki T, Yamanaka N, Manabe I, Tanaka T, Yokote K. Pancreatic β-cell glutaminase 2 maintains glucose homeostasis under the condition of hyperglycaemia. Sci Rep. 2023. 5;13(1):7291.
7. Kondo H, Ono H, Hamano H, Sone-Asano K, Ohno T, Takeda K, Ochiai H, Matsumoto A, Takasaki A, Hiraga C, Kumagai J, Maezawa Y, Yokote K. Insulin sensitivity initially worsens but later improves with aging in male C57BL/6N mice. J Gerontol A Biol Sci Med Sci. J Gerontol A Biol Sci Med Sci. 2023. 78(10):1785-1792.
8. Ide S, Maezawa Y, Yokote K. Updates on dyslipidemia in patients with diabetes. J Diabetes Investig 2023. 14(9):1041-1044.
9. Koshizaka M, Ishibashi R, Ishikawa K, Shoji M, Ide K, Ide S, Kato H, Teramoto N, Terayama R, Maezawa Y, Yokote K, PRIME-V Study Group. Urinary α1 microglobulin level is useful for selecting sodium-glucose transporter 2 inhibitor or metformin for visceral fat reduction in patients with type 2 diabetes. Diabetes Obes Metab 2023. 25(10):3071-3075.
10. Sakuma I, Nagano H, Hashimoto N, Fujimoto M, Nakayama A, Fuchigami T, Taki Y, Matsuda T, Akamine H, Kono S, Kono T, Yokoyama M, Nishimura M, Yokote K, Ogasawara T, Fujii Y, Ogawa S, Lee E, Miki T, Tanaka T. Identification of genotype-biochemical phenotype correlations associated with fructose 1,6-bisphosphatase deficiency. Commun Biol. 2023 Jul 28;6(1):787.
11. Sawada D, Kato H, Kaneko H, Kinoshita D, Funayama S, Minamizuka T, Takasaki A, Igarashi K, Koshizaka M, Takada-Watanabe A, Nakamura R, Aono K, Yamaguchi A, Teramoto N, Maeda Y, Ohno T, Hayashi A, Ide K, Ide S, Shoji M, Kitamoto T, Endo Y, Ogata H, Kubota Y, Mitsukawa N, Iwama A, Ouchi Y, Takayama N, Eto K, Fujii K, Takatani T, Shiohama T, Hamada H, Maezawa Y, Yokote K. Senescence-associated inflammation and inhibition of adipogenesis in subcutaneous fat in Werner syndrome. Aging (Albany NY). 2023. 15(19):9948-9964.
12. Ako J, Yokote K, Tsujita K, Tanigawa R, Kamei R, Suganami H; K-Clinical Study Group. Long-term Efficacy and Safety of K-924 Pitavastatin/Ezetimibe Fixed-dose Combination in Patients with Hypercholesterolemia: A Phase III, Multi-center, Open-label Trial. J Atheroscler Thromb. 2023. Online ahead of print.
13. Tsukagoshi-Yamaguchi A, Koshizaka M, Ishibashi R, Ishikawa K, Ishikawa T, Shoji M, Ide S, Ide K, Baba Y, Terayama R, Hattori A, Takemoto M, Ouchi Y, Maezawa Y, Yokote K; PRIME-V study group. Metabolomic analysis of serum samples from a clinical study on ipragliflozin and metformin treatment in Japanese patients with type 2 diabetes: Exploring human metabolites associated with visceral fat reduction. Pharmacotherapy. 202343(12):1317-1326.
14. Izuo N, Watanabe N, Noda Y, Saito T, Saido TC, Yokote K, Hotta H, Shimizu T. Insulin resistance induces earlier initiation of cognitive dysfunction mediated by cholinergic deregulation in a mouse model of Alzheimer's disease. Aging Cell. 2023;22(11):e13994.
15. Namiki T, Takemoto M, Hayashi A, Yamagata H, Ishikawa T, Yokote K, Li SY, Kubota M, Zhang BS, Yoshida Y, Matsutani T, Mine S, Machida T, Kobayashi Y, Terada J, Naito A, Tatsumi K, Takizawa H, Nakamura R, Kuroda H, Iwadate Y, Hiwasa T. Serum anti-PCK1 antibody levels are a prognostic factor for patients with diabetes mellitus. BMC Endocr Disord. 2023;23(1):239.
16. Kumagai J, Kiuchi M, Kokubo K, Yagyu H, Nemoto M, Tsuji K, Nagahata K, Sasaki A, Hishiya T, Onoue M, Shinmi R, Sonobe Y, Iinuma T, Yonekura S, Shinga J, Hanazawa T, Koseki H, Nakayama T, Yokote K, Hirahara K.The USP7-STAT3-granzyme-Par-1 axis regulates allergic inflammation by promoting differentiation of IL-5-producing Th2 cells. Proc Natl Acad Sci U S A. 2023 ;120(49):e2302903120.
17. Sakai S, Tanaka Y, Tsukamoto Y, Kimura-Ohba S, Hesaka A, Hamase K, Chin-Ling Hsieh, Kawakami E, Ono H, Yokote K, Yoshino M, Okuzaki D, Matsumura H, Fukushima A, Mita M, Nakane M, Doi M, Isaka Y, Kimura T. d-Alanine Affects the Circadian Clock to Regulate Glucose Metabolism in Kidney. Kidney360. 2023 Dec 15.
18. Ogawa W, Hirota Y, Miyazaki S, Nakamura T, Ogawa Y, Shimomura I, Yamauchi T, Yokote K; Creation Committee for Guidelines for the Management of Obesity Disease 2022 by Japan Society for the Study of Obesity (JASSO). Definition, criteria, and core concepts of guidelines for the management of obesity disease in Japan. Endocr J. 2023 Dec 20. Online ahead of print.
19. Suzuki S, Takahashi N, Sugo M, Ishiwata K, Ishida A, Watanabe S, Igarashi K, Ruike Y, Naito K, Fujimoto M, Koide H, Imamura Y, Sakamoto S, Ichikawa T, Kubota Y, Wada T, Yamazaki Y, Sasano H, Jun-Ichiro Ikeda , Tatsuno I, Yokote K.Challenges in the diagnosis of the enigmatic primary adrenal leiomyosarcoma: two case reports and review of the literature. BMC Endocr Disord. 2023 ;23(1):276.
20. Maezawa Y, Endo Y, Kono S, Ohno T, Nakamura Y, Teramoto N, Yamaguchi A, Aono K, Minamizuka T, Kato H, Ishikawa T, Koshizaka M, Takemoto M, Nakayama T, Yokote K. Weight loss improves inflammation by T helper 17 cells in an obese patient with psoriasis at high risk for cardiovascular events. J Diabetes Investig.2023. 14(9):1136-1139.
21. Ishibashi R, Hirayama K, Watanabe S, Okano K, Kuroda Y, Baba Y, Kanayama T, Ito C, Kasahara K, Aiba S, Iga R, Ohtani R, Inaba Y, Koshizaka M, Maezawa Y, Yokote K. Imeglimin-mediated glycemic control in maternally inherited deafness and diabetes. J Diabetes Investig. 2023. Online ahead of print.
22. Misawa T, Hitomi K, Miyata K, Tanaka Y, Fujii R, Chiba M, Loo TM, Hanyu A, Kawasaki H, Kato H, Maezawa Y, Yokote K, Nakamura AJ, Ueda K, Yaegashi N, Takahashi A. Identification of Novel Senescent Markers in Small Extracellular Vesicles. .Int J Mol Sci. 2023 ;24(3):2421.
23. Accili D, Du W, Kitamoto T, Kuo T, McKimpson W, Miyachi Y, Mukhanova M, Son J, Wang L, Watanabe H. Reflections on the state of diabetes research and prospects for treatment. Diabetology International. 2023;14(1):21-31
24. Fujimoto M, Watanabe S, Igarashi K, Ruike Y, Ishiwata K, Naito K, Ishida A, Koshizaka M, Suzuki S, Shiko Y, Koide H, Yokote K. Antihypertensive Effects of Esaxerenone in Older Patients with Primary Aldosteronism. Int J Hypertens. 2023 ;2023:6453933.
25. Watanabe H, Du W, Son J, Sui L, Asahara S-i, Kurland IJ, Kuo T, Kitamoto T, Miyachi Y, de Cabo R, Accili D. Cyb5r3-based mechanism and reversal of secondary failure to sulfonylurea in diabetes. Sci. Transl. Med. 2023;15:eabq4126
26. Li SY, Yoshida Y, Kubota M, Zhang BS, Matsutani T, Ito M, Yajima S, Yoshida K, Mine S, Machida T, Hayashi A, Takemoto M, Yokote K, Ohno M, Nishi E, Kitamura K, Kamitsukasa I, Takizawa H, Sata M, Yamagishi K, Iso H, Sawada N, Tsugane S, Iwase K, Shimada H, Iwadate Y, Hiwasa T. Utility of atherosclerosis-associated serum antibodies against colony-stimulating factor 2 in predicting the onset of acute ischemic stroke and prognosis of colorectal cancer. Front Cardiovasc Med.2023 ;10:1042272.
27. Kitagawa Y, Amemiya A, Ogata H, Koshizaka M, Shoji M, Maezawa Y, Akita S, Mitsukawa N, Yokote K. Quality of life in Werner syndrome and associated subjective foot/ankle symptoms: A cross-sectional survey. Geriatr Gerontol Int. 2023 ;23(3):188-193.
28. Yamagata H, Hayashi A, Yoshida Y, Koshizaka M, Onishi S, Yoshida T, Hiwasa T, Takemoto M. Association of high proprotein convertase subtilisin/kexin type 9 antibody level with poor prognosis in patients with diabetes: a prospective study.
Sci Rep. 2023 ;13(1):5391.
29. Kitamoto T, Accili D. Unraveling the mysteries of hepatic insulin signaling: deconvoluting the nuclear targets of insulin. Endocr J. 2023; 70(9):851-866.
30. Takemoto M, Hayashi A, Inaba Y, Tanaka T, Chun TH, Hayashi H, Kasama K, Saiki A, Sasaki A, Okazumi S, Matsubara H, Tatsuno I. Safety and effectiveness of metabolic surgery in older Japanese patients. Ann Gastroenterol Surg. 2023 May 22;7(5):750-756.
31. Ide S, Maezawa Y, Yokote K. Updates on dyslipidemia in patients with diabetes. Journal of Diabetes Investigation, 2023, 14(9), pp. 1041–1044
32. Fujimoto M, Watanabe S, Igarashi K, Ruike Y, Ishiwata K, Naito K, Ishida A, Suzuki S, Koide H, Yokote K. Antihypertensive effects of esaxerenone in older patients with primary aldosteronism. Running title: Esaxerenone responders in primary aldosteronism. International Journal of Hypertension. 2023 ;2023:6453933.
33. Sugisaki K, Uchida T, Iwama S, Okihara M, Akashi I, Kihara Y, Konno O, Kuroda M, Koike J, Iwamoto H, Oda T. Glomerular lipidosis as a feature of renal-limited macrophage activation syndrome in a transplanted kidney: a case report. BMC Nephrol. 2023 ;24(1):329.
34. Teranaka R, Fujimoto H, Masuda T, Kuroda M, Aoyagi Y, Nagashima T, Takada M, Sakakibara J, Yamada H, Yamamoto H, Kubota Y, Ohtsuka M. Ex vivo dual gene therapy using human adipocytes secreting anti-HER2 antibody on HER2-positive xenograft tumor models. Breast Cancer. 2023;30(6):1018-1027.
35. Suzuki S, Venkatesh D, Tanaka T, Prives C. GLS2 shapes ferroptosis in hepatocellular carcinoma. Oncotarget. 2023 ;14:900-903.
36. Takeuchi N, Imamura Y, Ishiwata K, Kanesaka M, Goto Y, Sazuka T, Suzuki S, Koide H, Sakamoto S, Ichikawa T. Cushing's syndrome in pregnancy in which laparoscopic adrenalectomy was safely performed by a retroperitoneal approach. IJU Case Rep. 2023 ;6(6):415-418.
37. Yook JS, Taxin ZH, Oikawa S, Fujimoto M, Kajimura S. Reply to Ren et al.: The role of a liver-specific mitochondrial carrier SLC25A47 in glucose homeostasis. Proc Natl Acad Sci U S A. 2023 ;120(32):e2307922120.
38. Shima M, Amano K, Ogawa Y, Yoneyama K, Ozaki R, Kobayashi R, Sakaida E, Saito M, Okamura T, Ito T, Hattori N, Higasa S, Suzuki N, Seki Y, Nogami K. A prospective, multicenter, open-label phase III study of emicizumab prophylaxis in patients with acquired hemophilia A. J Thromb Haemost. 2023 Mar;21(3):534-545. doi: 10.1016/j.jtha.2022.10.004. Epub 2022 Dec 22. PMID: 36696195.
39. Rizq O, Mimura N, Oshima M, Momose S, Takayama N, Itokawa N, Koide S, Shibamiya A, Miyamoto-Nagai Y, Rizk M, Nakajima-Takagi Y, Aoyama K, Wang C, Saraya A, Seimiya M, Watanabe M, Yamasaki S, Shibata T, Yamaguchi K, Furukawa Y, Chiba T, Sakaida E, Nakaseko C, Tamaru JI, Tai YT, Anderson KC, Honda H, Iwama A. UTX inactivation in germinal center B cells promotes the development of multiple myeloma with extramedullary disease. Leukemia. 2023 May 17. doi: 10.1038/s41375-023-01928-7. Epub ahead of print. PMID: 37198323.
40. Harada K, Onizuka M, Mori T, Shimizu H, Seo S, Aotsuka N, Takeda Y, Sekiya N, Kusuda M, Fujiwara S, Shiraiwa S, Shono K, Shingai N, Kanamori H, Momoki M, Takada S, Mukae J, Masuda S, Mitani K, Sakaida E, Tomikawa T, Takahashi S, Usuki K, Kanda Y. Prognostic factors for the development of lower respiratory tract infection after influenza virus infection in allogeneic hematopoietic stem cell transplantation recipients: A Kanto Study Group for Cell Therapy multicenter analysis. Int J Infect Dis. 2023 ;131:79-86.
41. Jo T, Yoshihara S, Okuyama Y, Fujii K, Henzan T, Kahata K, Yamazaki R, Takeda W, Umezawa Y, Fukushima K, Ashida T, Yamada-Fujiwara M, Hanajiri R, Yonetani N, Tada Y, Shimura Y, Nishikii H, Shiba N, Mimura N, Ando J, Sato T, Nakashima Y, Ikemoto J, Iwaki K, Fujiwara SI, Ri M, Nagamura-Inoue T, Tanosaki R, Arai Y. Risk factors for CAR-T cell manufacturing failure among DLBCL patients: A nationwide survey in Japan. Br J Haematol. 2023 ;202(2):256-266.
42. Qiang N, Ao J, Nakamura M, Chiba T, Kusakabe Y, Kaneko T, Kurosugi A, Kogure T, Ma Y, Zhang J, Ogawa K, Kan M, Iwanaga T, Sakuma T, Kanayama K, Kanzaki H, Kojima R, Nakagawa R, Kondo T, Nakamoto S, Muroyama R, Kato J, Mimura N, Ma A, Jin J, Kato N. Alteration of the tumor microenvironment by pharmacological inhibition of EZH2 in hepatocellular carcinoma. Int Immunopharmacol. 2023 ;118:110068.
43. Iwanaga T, Chiba T, Nakamura M, Kaneko T, Ao J, Qiang N, Ma Y, Zhang J, Kogure T, Yumita S, Ishino T, Ogawa K, Kan M, Nakagawa M, Fujiwara K, Fujita N, Sakuma T, Kanzaki H, Koroki K, Kusakabe Y, Inoue M, Kobayashi K, Kanogawa N, Kiyono S, Kondo T, Nakagawa R, Ogasawara S, Nakamoto S, Muroyama R, Kato J, Kanda T, Maruyama H, Mimura N, Honda T, Murayama T, Nakamura H, Kato N. Miglustat, a glucosylceramide synthase inhibitor, mitigates liver fibrosis through TGF-β/Smad pathway suppression in hepatic stellate cells. Biochem Biophys Res Commun. 2023 ;642:192-200.
44. Akahoshi Y, Tada Y, Sakaida E, Kusuda M, Doki N, Uchida N, Fukuda T, Tanaka M, Sawa M, Katayama Y, Matsuoka KI, Ozawa Y, Onizuka M, Kanda J, Kanda Y, Atsuta Y, Nakasone H. Novel risk assessment for the intensity of conditioning regimen in older patients. Blood Adv. 2023;7(17):4738-4747.
45. Sato A, Kobayashi M, Yusa N, Ogawa M, Shimizu E, Kawamata T, Yokoyama K, Ota Y, Ichinohe T, Ohno H, Mori Y, Sakaida E, Kondo T, Imoto S, Nannya Y, Mitani K, Tojo A. Clinical and prognostic features of Langerhans cell histiocytosis in adults. Cancer Sci. 2023;114(9):3687-3697.
46. Ando Y, Nishiyama H, Shimodaira H, Takano N, Sakaida E, Matsumoto K, Nakanishi K, Sakai H, Tsukamoto S, Komine K, Yasuda Y, Kato T, Fujiwara Y, Koyama T, Kitamura H, Kuwabara T, Yonezawa A, Okumura Y, Yakushijin K, Nozawa K, Goto H, Matsubara T, Hoshino J, Yanagita M; Committee of Clinical Practice Guidelines for the Management of Kidney Disease During Anticancer Drug Therapy 2022. Chapter 3: Management of kidney injury caused by cancer drug therapy, from clinical practice guidelines for the management of kidney injury during anticancer drug therapy 2022. Int J Clin Oncol. 2023 ;28(10):1315-1332.
47. Shimizu H, Najima Y, Kako S, Tanaka M, Fujiwara SI, Mori T, Usuki K, Gotoh M, Hagihara M, Tsukada N, Oniduka M, Takada S, Sakaida E, Fujisawa S, Onoda M, Aotsuka N, Yano S, Ohashi K, Takahashi S, Okamoto S, Kanda Y; Clinical significance of late CMV disease in adult patients who underwent allogeneic stem cell transplant. J Infect Chemother. 2023 ;29(12):1103-1108.
48. Rizq O, Mimura N, Oshima M, Momose S, Takayama N, Itokawa N, Koide S, Shibamiya A, Miyamoto-Nagai Y, Rizk M, Nakajima-Takagi Y, Aoyama K, Wang C, Saraya A, Ito R, Seimiya M, Watanabe M, Yamasaki S, Shibata T, Yamaguchi K, Furukawa Y, Chiba T, Sakaida E, Nakaseko C, Tamaru JI, Tai YT, Anderson KC, Honda H, Iwama A. Correction: UTX inactivation in germinal center B cells promotes the development of multiple myeloma with extramedullary disease. Leukemia. 2023 ;37(9):1952.
49. Muto T, Walker CS, Agarwal P, Vick E, Sampson A, Choi K, Niederkorn M, Ishikawa C, Hueneman K, Varney M, Starczynowski DT. Inactivation of p53 provides a competitive advantage to del(5q) myelodysplastic syndrome hematopoietic stem cells during inflammation. Haematologica. 2023;108(10):2715-2729.

和文

1. 佐久間一基,横手幸太郎 脂質異常症治療薬.Pocket Drugs 2023 2023:450-9.
2. 横手幸太郎 特集ドクターにお聞きしました 全身の血管や臓器にリスク コレステロール. すこぶる 冬号 2023;225:6-11.
3. 岡田洋右, 横手幸太郎 対談 糖尿病患者における動脈硬化性疾患の予防と管理 動脈硬化性疾患予防ガイドライン2022より Calm 2023;10(1)36-46.
4. 横手幸太郎 寄稿 肥満症治療薬の現状と今後 肥満症治療学展望. 2023;10(3)41.
5. 金子ひより, 石川崇広, 前澤善朗, 横手幸太郎 高血圧症,脂質異常症メタボリックシンドローム,サルコペニア肥満 日本臨牀 2023;81(4)557-564.
6. 南塚拓也,横手幸太郎 多価不飽和脂肪酸 臨床雑誌内科 増大号 特集プライマリケア医に必要な情報をまるっと整理 くすりの使い方便利帳 2023;131(4)876-9
7. 横手幸太郎 11月例会 千葉大病院におけるコロナとの闘いと明日への展望 千葉県経済同友会 2023春会報 2023;1-6
8. 横手幸太郎 肥満最新情報 NHKテキスト きょうの健康5月号. 2023;10-27
9. 横手幸太郎 特集 横手幸太郎病院長インタビュー いのはなハーモニー第68号. 2023;2-3
10. 横手幸太郎 30年ぶりに肥満症新薬が登場 効果的な減量のコツとは 日経ヘルス2023夏号. 2023;74-75.
11. 北本匠、横手幸太郎. 肥満症に対する減量介入とがんリスク低減:適切な減量治療の確立への課題. 医学のあゆみ 2023; 286(10) 860-866.
12. 横手幸太郎. 肥満症総論.特集:肥満症治療のUpdate. メディカル・サイエンス・ダイジェスト2023; 49(11)574-576.
13. 横手幸太郎.医師の働き方改革:大学病院から見た医師の働き方改革.社会保険旬報 2023; 12, 6-11.
14. 横手幸太郎.巻頭言:卒前の臨床実習と専門職連携教育の充実を. 日経メディカル特別編集版2023; 12,3.
15. 横手幸太郎(監修) ここが知りたい! 内分泌疾患診療ハンドブックVer.3, 中外医学社, 東京, 2023.
16. 横手幸太郎(単行本監修)からだがみえる 人体の構造と機能,MEDIC MEDIA, 東京, 2023.
17. 横手幸太郎(単行本監修)健康図解 新装版 今すぐできる! コレステロールを下げる40のルール, 株式会社Gakken, 東京, 2023;1
18. 金子ひより, 石川崇広, 前澤善朗 横手太郎. 日本臨床 Ⅳ. 高齢者糖尿病の合併症・併存
19. 黒田正幸、横手幸太郎. 家族性LCAT 欠損症を対象としたex vivo 脂肪細胞遺伝子治療 遺伝子治療開発研究ハンドブック第2版、第1章Ex vivo遺伝子治療、第3節、脂肪細胞を標的とするex vivo 遺伝子治療、p290-p296、株式会社 エヌ・ティー・エス、発行日2023/4/30
20. 渡邉涼香, 鈴木佐和子. 下垂体機能検査の実際Q&A. 糖尿病・内分泌プラクティスWeb 研修道場 ポイントはここだ! (2023年11・12月号) a0091-a0091 2023年12月
21. 鈴木 佐和子, 横手 幸太郎. 特集 徹底攻略! 副腎腫瘍2023―泌尿器科医が知っておくべき重要ポイント〈ピックアップ〉 両側副腎皮質大結節性過形成. 臨床泌尿器科 77(10) 828-832 2023年9月
22. 堺田惠美子.日本骨髄腫患者の会 『がんばりまっしょい』 2023年1月発刊 P12-27. 巻頭トピックス.「患者と医師で考える治療目標!ベクトルをあわせよう」
23. 堺田惠美子. POEMS症候群の病態・診断・治療 2023年7月発刊 日本内科学会雑誌. 112 (7), 1223-1230.
24. 加藤怜, 三村尚也. 『日本臨牀』月刊誌2023年6月 特集 多発性骨髄腫 update-診断・治療の最新動向- 「骨髄腫モデルマウス」. p863-868. 日本臨牀社
25. 久保寺愛, 大島渚, 堺田惠美子. 『日本臨牀』月刊誌2023年6月 特集 多発性骨髄腫 update-診断・治療の最新動向-「POEMS症候群, Castleman病, TAFRO症候群の病態と治療の進歩」 p933-938. 日本臨牀社
26. Jo T, Henzan T, Tomizawa D, Yoshihara S, Kahata K, Yamada-Fujiwara M, Okuyama Y, Shiba N, Fujii K, Umezawa Y, Yamazaki R, Takeda W, Hanajiri R, Fukushima K, Mimura N, Ikemoto J, Iwaki K, Yonetani N, Fujiwara SI, Ri M, Nagamura-Inoue T, Tanosaki R, Arai Y. [Manufacturing results of tisagenlecleucel for acute lymphoblastic leukemia: a survey by the CAR-T cell therapy taskforce of the Japan Society of Transfusion Medicine and Cell Therapy]. Rinsho Ketsueki. 2023;64(5):331-337. Japanese.
27. Isshiki Y, Oshima M, Mimura N, Sakaida E, Iwama A. [Identification of transcriptional features and surface markers of plasma cell clones in POEMS syndrome by single-cell RNA sequencing]. Rinsho Ketsueki. 2023;64(7):581-585. Japanese.
28. Muto T. [Role of innate immune signaling and inflammation in the pathogenesis of myeloid malignancies]. Rinsho Ketsueki. 2023;64(9):962-969. Japanese.

2022年業績

英文

1. Kuroda M., Hori M., Maezawa Y., Kubota Y., Mitsukawa N., Shiko Y., Ozawa Y., Kawasaki Y., Saito Y., Hanaoka H., Yokote K. LCAT-trial-24 weeks: Protocol for a clinical study to evaluate the safety of regenerative medicine and gene therapy by the autologous transplantation of human lecithin:cholesterol acyltransferase gene-transduced human pre-adipocytes. Contemp Clin Trials Commun. 2022 Jun 9;28:100946.
2. Takeda T., Ide T., Okuda D., Kuroda M., Asada S., Kirinashizawa M., Yamamoto M., Miyoshi J., Yokote K., Mizutani N. A novel homozygous frameshift mutation in the APOA1 gene associated with marked high-density lipoprotein deficiency. J Clin Lipidol. 2022 Jul-Aug;16(4):423-433..
3. Nishikawa R, Furuhashi M, Hori M, Ogura M, Harada-Shiba M, Okada T, Koseki M, Kujiraoka T, Hattori H, Ito R, Muranaka A, Kokubu N, Miura T. A Resuscitated Case of Acute Myocardial Infarction with both Familial Hypercholesterolemia Phenotype Caused by Possibly Oligogenic Variants of the PCSK9 and ABCG5 Genes and Type I CD36 Deficiency. J Atheroscler Thromb. 29: 551-557, 2022
4. Tada H, Hori M, Matsuki K, Ogura M, Nohara A, Kawashiri MA, Harada-Shiba M. Achilles Tendon Thickness Assessed by X-ray Predicting a Pathogenic Mutation in Familial Hypercholesterolemia Gene. J Atheroscler Thromb. 2022; 29(6): 816-824.
5. Nishikawa R, Furuhashi M, Hori M, Ogura M, Harada-Shiba M, Okada T, Koseki M, Kujiraoka T, Hattori H, Ito R, Muranaka A, Kokubu N, Miura T. A Resuscitated Case of Acute Myocardial Infarction with both Familial Hypercholesterolemia Phenotype Caused by Possibly Oligogenic Variants of the PCSK9 and ABCG5 Genes and Type I CD36 Deficiency. J Atheroscler Thromb. 29: 551-557, 2022
6. Tada H, Hori M, Matsuki K, Ogura M, Nohara A, Kawashiri MA, Harada-Shiba M. Achilles Tendon Thickness Assessed by X-ray Predicting a Pathogenic Mutation in Familial Hypercholesterolemia Gene. J Atheroscler Thromb. 2022; 29(6): 816-824.
7. Ogura M, Harada-Shiba M, Masuda D, Arai H, Bujo H, Ishibashi S, Daida H, Koga N, Oikawa S, Yamashita S. Factors Associated with Carotid Atherosclerosis and Achilles Tendon Thickness in Japanese Patients with Familial Hypercholesterolemia: A Subanalysis of the Familial Hypercholesterolemia Expert Forum (FAME) Study. J Atheroscler Thromb. 2022; 29(6): 906-922.
8. Tada H, Kurashina T, Ogura M, Takegami M, Miyamoto Y, Arai H, Harada-Shiba M, Ishibashi S. Prospective Registry Study of Primary Dyslipidemia (PROLIPID): Rationale and Study Design. J Atheroscler Thromb. 2022; 29(6): 953-969.
9. Michikura M, Ogura M, Hori M, Matsuki K, Makino H, Hosoda K, Harada-Shiba M. Association between Achilles tendon softness and atherosclerotic cardiovascular disease in patients with familial hypercholesterolemia. .J Atheroscler Thromb. 2022 Nov 1;29(11):1603-1612.
10. Matsumoto E, Oniki K, Ota-Kontani A, Seguchi Y, Sakamoto Y, Kaneko T, Imafuku T, Maeda H, Watanabe H, Maruyama T, Ogata Y, Yoshida M, Harada-Shiba M, Saruwatari J, Ogura M. Additive effects of drinking habits and a susceptible genetic polymorphism on cholesterol efflux capacity. J Atheroscler Thromb. 2022 Mar 4. doi: 10.5551/jat.63277. Online ahead of print.
11. Funabashi S, Kataoka Y, Hori M, Ogura M, Doi T, Noguchi T, Harada-Shiba M. Characterization of Polyvascular Disease in Heterozygous Familial Hypercholesterolemia: Its Association with Circulating Lipoprotein(a) Levels. J Am Heart Assoc. 2022; 11(16):e025232.
12. Ogura M. HDL, cholesterol efflux, and ABCA1: Free from good and evil dualism. J Pharmacol Sci. 2022 Oct;150(2):81-89
13. Michikura M, Hori M, Ogura M, Hosoda K, Harada-Shiba M.The impact of gene variants on the thickness and softness of the Achilles tendon in familial hypercholesterolemia. Atherosclerosis. 2022 Oct;358:41-46. doi: 10.1016/j.atherosclerosis.2022.08.014. Epub 2022 Aug 30. PMID: 36087353
14. Hori M, Takahashi A, Hosoda K, Ogura M, Harada-Shiba M. A low-frequency APOB p.(Pro955Ser) variant contributes to the severity of/variability in familial hypercholesterolemia. J Clin Endocrinol Metab. 2022 Oct 3:dgac572. doi: 10.1210/clinem/dgac572. Online ahead of print.PMID: 36190978
15. Ishikawa T, Yamamoto D, Kato T, Mori T, Machida T, Ogura M. Hyponatremia due to hypopituitarism caused by cerebral aneurysm. Age Ageing. 2022 Dec 5;51(12):afac291. doi: 10.1093/ageing/afac291. PMID: 36580386
16. Ogura M. The Reason is Still Unclear. J Atheroscler Thromb. 2022 Jan 1;29(1):3-4.
17. Yoshida H, Hirowatari Y, Ogura M, Harada-Shiba M.Current concept and residual issues of lipoprotein(a) determination for a cardiovascular risk factor. Eur J Clin Invest. 2022 Jan;52(1):e13700.
18. Shintaro Ide, Kana Ide, Koki Abe, Yoshihiko Kobayashi, Hiroki Kitai, Jennifer McKey, Sarah A. Strausser, Lori L. O’Brien, Aleksandra Tata, Purushothama Rao Tata, Tomokazu Souma. Sex differences in resilience to ferroptosis underlie sexual dimorphism in kidney injury and repair .Cell Reports. 2022,;41(6), 111610
19. Xiaohan Lu, Jiandong Zhang, Yi Wen, Jiafa Ren, Robert Griffiths, Nathan P. Rudemiller, Shintaro Ide, Tomokazu Souma, Steven D. Crowley. Type 1 Angiotensin Receptors on CD11c-Expressing Cells Protect Against Hypertension by Regulating Dendritic Cell–Mediated T Cell Activation. Hpertension. 2022;79, 1227–1236
20. Jamie R Privratsky, Shintaro Ide, Yanting Chen, Hiroki Kitai, Jiafa Ren, Helene Fradin, Xiaohan Lu, Tomokazu Souma, Steven D Crowley. A macrophage-endothelial immunoregulatory axis ameliorates septic acute kidney injury. Kidney Int. 2022;S0085-2538(22)00916-4.
21. Gal Finer, Yoshiro Maezawa, Shintaro Ide, Tuncer Onay, Tomokazu Souma, Rizaldy Scott, Xiaoyan Liang, Xiangmin Zhao, Gaurav Gadhvi, Deborah Winter, Susan E. Quaggin, Tomoko Hayashida. Stromal Transcription Factor 21 Regulates Development of the Renal Stroma via Interaction with Wnt/β-Catenin signaling. Kidney360. 2022; 3(7),1228-1241
22. Kana Ide, Tomokazu Souma. In vivo assessment of ferroptosis and ferroptotic stress in mice. Current Protocols. 2022; 2, e413.
23. Wen Du, Junqiang Wang, Taiyi Kuo, Liheng Wang, Wendy M McKimpson, Jinsook Son, Hitoshi Watanabe, Takumi Kitamoto, Yunkyoung Lee, Remi J Creusot, Lloyd E Ratner, Kasi McCune , Ya-Wen Chen, Brendan H Grubbs , Matthew E Thornton, Jason Fan, Nishat Sultana, Bryan S Diaz, Iyshwarya Balasubramanian, Nan Gao, Sandro Belvedere, Domenico Accili. Pharmacological conversion of gut epithelial cells into insulin-producing cells lowers glycemia in diabetic animals. J Clin Invest. 2022;15;132(24):e162720. doi: 10.1172/JCI162720.
24. María Concepción Izquierdo, Niroshan Shanmugarajah, Samuel X Lee, Michael J Kraakman, Marit Westerterp, Takumi Kitamoto, Michael Harris, Joshua R Cook, Galina A Gusarova, Kendra Zhong, Elijah Marbuary, InSug O-Sullivan, Nikolaus Rasmus, Stefania Camastra, Terry G Unterman, Ele Ferrannini, Barry E Hurwitz, Rebecca A Haeusler. Hepatic FoxOs link insulin signaling with plasma lipoprotein metabolism through an apolipoprotein M/sphingosine-1-phosphate pathway. J Clin Invest.2022; 132(7)doi:10.1172/JCI146219
25. Takumi Kitamoto, Yun-Kyoung Lee, Nishat Sultana, Hitoshi Watanabe, Wendy M McKimpson, Wen Du, Jason Fan, Bryan Diaz, Hua V Lin, Rudolph L Leibel, Sandro Belvedere, Domenico Accili. Chemical induction of gut β-like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetes. Mol Metab. 2022;66:101624. doi:10.1016/j.molmet.2022.101624
26. Takumi Kitamoto, Tetsuo Nishikawa. Clinical Translationality of KCNJ5 Mutation in Aldosterone Producing Adenoma. Review Int J Mol Sci. 2022 ;23(16):9042. doi: 10.3390/ijms23169042.
27. Yun-Kyoung Lee, Wen Du, Yaohui Nie, Bryan Diaz, Nishat Sultana, Takumi Kitamoto, Rudolph L Leibel, Domenico Accili, Sandro Belvedere. Single-agent FOXO1 inhibition normalizes glycemia and induces gut β-like cells in streptozotocin-diabetic mice. Mol Metab 2022;66:101618. doi: 10.1016/j.molmet.2022.101618. Epub 2022 Oct 22.
28. Wendy M McKimpson, Taiyi Kuo, Takumi Kitamoto, Sei Higuchi, Jason C Mills , Rebecca A Haeusler, Domenico Accili. FOXO1 Is Present in Stomach Epithelium and Determines Gastric Cell Distribution. Gastro Hep Adv. 2022;1(5):733-745. doi: 10.1016/j.gastha.2022.05.005. Epub 2022 May 14.
29. Yamaguchi M, Takahashi-Nakaguchi A, Uematsu K, Naito Kumiko, Sato-Okamoto M, Ishiwata K, Naraoka S, Chibana H. Electron microscopy of mouse tissues by sandwich freezing and freeze-substitution. Cytologia 87: 149-155, 2022.
30. Yamamotoya T, Hasei S, Akasaka Y, Ohata Y, Nakatsu Y, Kanna M, Fujishiro M, Sakoda H, Ono H, Kushiyama A, Misawa H, Asano T. Involvement of neuronal and muscular Trk-fused gene (TFG) defects in the development of neurodegenerative diseases. Sci Rep. 2022 Feb 4;12(1):1966.
31. Kusunose K, Yoshida H, Tanaka A, Teragawa H, Akasaki Y, Fukumoto Y, Eguchi K, Kamiya H, Kario K, Yamada H, Sata M, Node K; PRIZE Study Investigators. Effect of febuxostat on left ventricular diastolic function in patients with asymptomatic hyperuricemia: a sub analysis of the PRIZE Study. Hypertens Res. 2022;45(1):106-15.
32. Watanabe Y, Yamaguchi T, Tanaka S, Sasaki A, Naitoh T, Matsubara H, Yokote K, Okazumi S, Ugi S, Yamamoto H, Ohta M, Ishigaki Y, Kasama K, Seki Y, Tsujino M, Shirai K, Miyazaki Y, Masaki T, Nagayama D, Saiki A, Tatsuno I. Characteristics of Childhood Onset and Post-Puberty Onset Obesity and Weight Regain after Laparoscopic Sleeve Gastrectomy in Japanese Subjects: A Subgroup Analysis of J-SMART. Obes Facts. 2022;15(4):498-507.
33. Kaneko H, Takemoto M, Murakami H, Ihara K, Kosaki R, Motegi SI, Taniguchi A, Matsuo M, Yamazaki N, Nishigori C, Takita J, Koshizaka M, Maezawa Y, Yokote K. Rothmund-Thomson syndrome investigated by two nationwide surveys in Japan. Pediatr Int. 2022;64(1):e15120.
34. Kageyama T, Tanaka S, Etori K, Hattori K, Miyachi K, Kasuya T, Iwamoto T, Ikeda K, Igari H, Yokote K, Nakajima H. Immunological features that associate with the strength of antibody responses to BNT162b2 mRNA vaccine against SARS-CoV-2. Vaccine. 2022;40(14):2129-33.
35. Maezawa Y, Koshizaka M, Kato H, Yokote K Clinical and Basic Biology of Werner Syndrome, the Model Disease of Human Aging. Aging Mechanisms II. 2022:33-60.
36. Kato H, Maezawa Y, Nishijima D, Iwamoto E, Takeda J, Kanamori T, Yamaga M, Mishina T, Takeda Y, Izumi S, Hino Y, Nishi H, Ishiko J, Takeuchi M, Kaneko H, Koshizaka M, Mimura N, Kuzuya M, Sakaida E, Takemoto M, Shiraishi Y, Miyano S, Ogawa S, Iwama A, Sanada M, Yokote K. A high prevalence of myeloid malignancies in progeria with Werner syndrome is associated with p53 insufficiency. Exp Hematol. 2022;109:11-7.
37. Tatsumi T, Oshitari T, Takatsuna Y, Ishibashi R, Koshizaka M, Shiko Y, Baba T, Yokote K, Yamamoto S. Sodium-Glucose Co-Transporter 2 Inhibitors Reduce Macular Edema in Patients with Diabetes mellitus. Life (Basel). 2022;12(5):692.
38. Shoda J, Tanaka S, Etori K, Hattori K, Kasuya T, Ikeda K, Maezawa Y, Suto A, Suzuki K, Nakamura J, Maezawa Y, Takemoto M, Betsholtz C, Yokote K, Ohtori S, Nakajima H. Semaphorin 3G exacerbates joint inflammation through the accumulation and proliferation of macrophages in the synovium. Arthritis Res Ther. 2022;24(1):134.
39. Kato H, Koshizaka M, Kaneko H, Maezawa Y, Yokote K. Lifetime extension and the recent cause of death in Werner syndrome: a retrospective study from 2011 to 2020. Orphanet J Rare Dis. 2022;17(1):226. IF3.453
40. Wilding JPH, Batterham RL, Davies M, Van Gaal LF, Kandler K, Konakli K, Lingvay I, McGowan BM, Oral TK, Rosenstock J, Wadden TA, Wharton S, Yokote K, Kushner RF; STEP 1 Study Group. Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension. Diabetes Obes Metab. 2022;24(8):1553-64.
41. Kuroda M, Hori M, Maezawa Y, Kubota Y, Mitsukawa N, Shiko Y, Ozawa Y, Kawasaki Y, Saito Y, Hanaoka H, Yokote K. LCAT-trial-24 weeks: Protocol for a clinical study to evaluate the safety of regenerative medicine and gene therapy by the autologous transplantation of human lecithin:cholesterol acyltransferase gene-transduced human pre-adipocytes. Contemp Clin Trials Commun. 2022;28:100946.
42. Suzuki S, Ruike Y, Ishiwata K, Naito K, Igarashi K, Ishida A, Fujimoto M, Koide H, Horiguchi K, Tatsuno I, Yokote K. Clinical Usefulness of the Growth Hormone-Releasing Peptide-2 Test for Hypothalamic-Pituitary Disorder. J Endocr Soc. 2022;6(8):bvac088.
43. Iwamura C, Hirahara K, Kiuchi M, Ikehara S, Azuma K, Shimada T, Kuriyama S, Ohki S, Yamamoto E, Inaba Y, Shiko Y, Aoki A, Kokubo K, Hirasawa R, Hishiya T, Tsuji K, Nagaoka T, Ishikawa S, Kojima A, Mito H, Hase R, Kasahara Y, Kuriyama N, Tsukamoto T, Nakamura S, Urushibara T, Kaneda S, Sakao S, Tobiume M, Suzuki Y, Tsujiwaki M, Kubo T, Hasegawa T, Nakase H, Nishida O, Takahashi K, Baba K, Iizumi Y, Okazaki T, Kimura MY, Yoshino I, Igari H, Nakajima H, Suzuki T, Hanaoka H, Nakada TA, Ikehara Y, Yokote K, Nakayama T. Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2-induced lung exudative vasculitis and predicts COVID-19 severity. Proc Natl Acad Sci U S A. 2022;119(33):e2203437119.
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1. 佐久間一貴,横手幸太郎 脂質異常症治療薬 Pocket Drugs 2022 2021:441-51.
2. 横手幸太郎 コレステロール 異常値は動脈硬化を早めます.すこぶる 冬号 2022;221:6-11.
3. 寺本直弥,前澤善朗,横手幸太郎 (訳と紹介)糖尿病を合併したCOVID-19感染者における血糖値の閾値と予後の関連- 連続血糖モニターを用いたレトロスペクティブな探索研究-. 糖尿病プラクティス 2022;39(1):82-6.
4. 横手幸太郎 代謝疾患 最近の動向. 今日の治療指針 私はこう治療している 2022:722-3.
5. 横手幸太郎,猪狩英俊,中島裕史 COVID-19ワクチンに対する免疫応答:千葉大学病院における検討から.日本老年医学会雑誌 2022;59(1):22-6.
6. 落合英俊,小野啓,横手幸太郎 肥満症.診療ガイドラインUP-TO-DATA 2022-2023. メディカルレビュー社,東京,2022:417-22.
7. 横手幸太郎 間違いだらけのコレステロール対策.日経ヘルス 春号 2022;26(6):62-5.
8. 横手幸太郎,湯澤由紀夫 地域に医師を派遣している大学病院は,医師の働き方改革にどう対応するか. 病院 2022;81(2):130-3.
9. 横手幸太郎 大学病院における医師の働き方改革. カレントテラピー 2022;40(4):22-5.
10. 横手幸太郎 トップインタビュー 日本肥満学会理事長に聞く. Obesity Report 2022;10:1-2.
11. 寺本直弥,前澤善朗,横手幸太郎 心血管腎合併症予防を目指す糖尿病治療戦略. 循環器内科 2022;91(5):526-33.
12. 横手幸太郎 理事長就任のご挨拶. 日本肥満学会誌 肥満研究 2022;28(1):5-6.
13. 横手幸太郎 加齢と肥満に立脚した糖尿病合併症の研究. 糖尿病合併症 2022;3(1):7-15.
14. 塚越彩乃,前澤善朗,横手幸太郎 サルコペニア・フレイルとSGLT2阻害薬. 腎臓内科 2022;16(1):59-66.
15. 小野啓,横手幸太郎 高度肥満症を合併した糖尿病. 糖尿病コンサルテーションブック 2022:112-7.
16. 鈴木佐和子,横手幸太郎 副腎疾患と糖尿病. 糖尿病 2022;65(7):357-60.
17. 五十嵐活志,小出尚史,横手幸太郎 甲状腺クリーゼを疑うポイントは?. 2ページで診療が変わる! 糖尿病・内分泌疾患 ナレッジ100,南山堂,東京,2022:210-1.
18. 五十嵐活志,小出尚史,横手幸太郎 粘液水腫性昏睡を疑うポイントは?. 2ページで診療が変わる! 糖尿病・内分泌疾患 ナレッジ100,南山堂,東京,2022:212-3.
19. 五十嵐活志,小出尚史,横手幸太郎 副腎不全を疑うポイントは?. 2ページで診療が変わる! 糖尿病・内分泌疾患 ナレッジ100,南山堂,東京,2022:214-5.
20. 五十嵐活志,小出尚史,横手幸太郎 褐色細胞腫クリーゼを疑うポイントは?. 2ページで診療が変わる! 糖尿病・内分泌疾患 ナレッジ100,南山堂,東京,2022:216-7
21. 横手幸太郎(編集,序文) PM基礎・治療,ライフ・サイエンス,東京,2022;42(9):815.
22. 横手幸太郎(編集,序文) Geriatric Medicine, ライフ・サイエンス,東京,2022;60(10):867.
23. 小倉正恒. 「FHホモ接合体診療の進歩」 Medical Science Digest 2022 48(6): 20-23.
24. 小倉正恒. 「コレステロール引き抜き能~その臨床的意義と課題~」 日本臨床検査医学会誌 2022 70: 307-313
25. 小倉正恒. 「あぶらの善悪を考える」 浦和医師会報 2022 745: 57-60
26. 藤岡由夫、木庭新治、小倉正恒、吉田博.(特別座談会)脂質異常症-臨床検査に関するトピックス-本邦で進む脂質異常症の検査、治療、そして標準化作業.Vita.2022; 39(4): 1-26.
27. 堺田惠美子. 『血液疾患 最新の治療 2023-2025』 巻頭トピックス-11 POEMS症候群. 2022年9月発刊
28. 西原彩佳, 塚本祥吉, 堺田惠美子. 特集 「Onco-Nephrology (悪性腫瘍治療と腎機能障害)」 話題 抗がん剤・抗悪性腫瘍治療による腎機能障害 「造血幹細胞移植における腎障害:病態と対策」
29. 堺田惠美子. 『今日の治療指針 2023年版』 アミロイドーシス.
30. 堺田惠美子. 『日本医師会雑誌』 第151巻・特別号(1)(生涯教育シリーズ102)『血液疾患のすべて』 Ⅸ章. 多発性骨髄腫と類縁疾患 5. POEMS症候群
31. 西原彩佳, 塚本祥吉, 堺田惠美子. 月刊『血液内科』 特集 「多発性骨髄腫および類縁疾患の病態解析と治療の進歩」 話題 POEMS症候群の病態解析と治療の進歩 第84巻第4号(2022年4月発刊) 84(4): 543-549, 2022
32. 柴宮明日香, 三村尚也. 月刊『血液内科』 特集 「多発性骨髄腫および類縁疾患の病態と治療の進歩」 第84巻第4号(2022年4月発刊)
33. 李 千尋, 三村尚也, 堺田惠美子. 月刊『血液内科』 特集「血液疾患における抗体医薬と免疫細胞療法の新たな展開」 びまん性大細胞型B細胞リンパ腫に対するCAR-T細胞療法の臨床効果. 第84巻第7号(2022年7月発刊)
34. 三村尚也. 日本輸血・細胞治療学会 学会認定・アフェレーシスナース制度指定カリキュラム Ⅳ. 末梢血幹細胞採取 1.造血幹細胞とその動員(基礎)
35. 中世古知昭, 大和田千桂子, 堺田惠美子.POEMS症候群. EBM血液疾患の治療2023-2024. (2022年10月発刊) 
36. 石井改、塚本祥吉、堺田惠美子. マルチパラメーターフローサイトメトリーによる多発性骨髄腫およびPOEMS症候群クローンの検出 『血液内科』 第84巻 第5号. P1-6, 2(2022年5月発刊)
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2021年業績

英文

1. Nagai Y, Mimura N, Rizq O, Isshiki Y, Oshima M, Rizk M, Saraya A, Koide S, Nakajima-Takagi Y, Miyota M, Chiba T, Oshima-Hasegawa N, Muto T, Tsukamoto S, Mitsukawa S, Takeda Y, Ohwada C, Takeuchi M, Iseki T, Nakaseko C, Lennox W, Sheedy J, Weetall M, Yokote K, Iwama A, Sakaida E. The combination of the tubulin binding small molecule PTC596 and proteasome inhibitors suppresses the growth of myeloma cells. Sci Rep. 2021; 11(1):2074.
2. Koshizaka M, Ishikawa K, Ishibashi R, Takahashi S, Sakamoto K, Yokoh H, Baba Y, Ide S, Ide K, Ishikawa T, Onishi S, Kobayashi K, Takemoto M, Horikoshi T, Shimofusa R, Maezawa Y, Yokote K. Comparison of visceral fat reduction by ipragliflozin and metformin in elderly type 2 diabetes patients: Sub-analysis of a randomized-controlled study. Diabetes Ther. 2021;12(1):183-96.
3. Kayamori K, Nagai Y, Zhong C, Kaito S, Shinoda D, Koide S, Kuribayashi W, Oshima M, Nakajima-Takagi Y, Yamashita M, Mimura N, Becker HJ, Izawa K, Yamazaki S, Iwano S, Miyawaki A, Ito R, Tohyama K, Lennox W, Sheedy J, Weetall M, Sakaida E, Yokote K, Iwama A. DHODH inhibition synergizes with DNA-demethylating agents in the treatment of myelodysplastic syndromes. Blood Adv. 2021;5(2):438-50.
4. Yamashita S, Okazaki M, Okada T, Masuda D, Yokote K, Arai H, Araki E, Ishibashi S. Distinct differences in lipoprotein particle number evaluation between GP-HPLC and NMR: analysis in dyslipidemic patients administered a selective PPARα modulator, pemafibrate. J Atheroscler Thromb. 2021;28(9):974-96.
5. Koshizaka M, Ishikawa K, Ishibashi R, Maezawa Y, Sakamoto K, Uchida D, Nakamura S, Yamaga M, Yokoh H, Kobayashi A, Onishi S, Kobayashi K, Ogino J, Hashimoto N, Tokuyama H, Shimada F, Ohara E, Ishikawa T, Shoji M, Ide S, Ide K, Baba Y, Hattori A, Kitamoto T, Horikoshi T, Shimofusa R, Takahashi S, Nagashima K, Sato Y, Takemoto M, Newby LK, Yokote K; PRIME-V study group. Effects of ipragliflozin versus metformin in combination with sitagliptin on bone and muscle in Japanese patients with type 2 diabetes mellitus: Subanalysis of a prospective, randomized, controlled study (PRIME-V study). J Diabetes Investig. 2021;12(2):200-6.
6. Ishikawa T, Takemoto M, Akimoto Y, Takada-Watanabe A, Yan K, Sakamoto K, Maezawa Y, Suguro M, He L, Tryggvason K, Betsholtz C, Yokote K. A novel podocyte protein, R3h domain containing-like, inhibits TGF-β-induced p38 MAPK and regulates the structure of podocytes and glomerular basement membrane. J Mol Med (Berl). 2021;99(6):859-76.
7. Takemoto M, Yokote K. Preface to management guideline for Werner syndrome 2020. Geriatr Gerontol Int. 2021;21(2):131-2.
8. Tsukamoto K, Takemoto M, Kubota Y, Taniguchi T, Motegi SI, Taniguchi A, Nakagami H, Maezawa Y, Koshizaka M, Kato H, Mori S, Kuzuya M, Yokote K. Management guideline for Werner syndrome 2020. 1. Dyslipidemia and fatty liver associated with Werner syndrome. Geriatr Gerontol Int. 2021;21(2):133-8.
9. Kuzuya M, Takemoto M, Kubota Y, Taniguchi T, Motegi SI, Taniguchi A, Nakagami H, Maezawa Y, Koshizaka M, Kato H, Mori S, Tsukamoto K, Yokote K. Management guideline for Werner syndrome 2020. 2. Sarcopenia associated with Werner syndrome. Geriatr Gerontol Int. 2021;21(2):139-41.
10. Takemoto M, Kubota Y, Taniguchi T, Motegi SI, Taniguchi A, Nakagami H, Maezawa Y, Koshizaka M, Kato H, Tsukamoto K, Mori S, Kuzuya M, Yokote K. Management guideline for Werner syndrome 2020. 3. Diabetes associated with Werner syndrome. Geriatr Gerontol Int. 2021;21(2):142-5.
11. Mori S, Takemoto M, Kubota Y, Taniguchi T, Motegi SI, Taniguchi A, Nakagami H, Maezawa Y, Koshizaka M, Kato H, Tsukamoto K, Kuzuya M, Yokote K. Management guideline for Werner syndrome 2020. 4. Osteoporosis associated with Werner syndrome. Geriatr Gerontol Int. 2021;21(2):146-9.
12. Taniguchi T, Takemoto M, Kubota Y, Motegi SI, Taniguchi A, Nakagami H, Maezawa Y, Koshizaka M, Kato H, Mori S, Tsukamoto K, Kuzuya M, Yokote K. Management guideline for Werner syndrome 2020. 5. Infection associated with Werner syndrome. Geriatr Gerontol Int. 2021;21(2):150-2.
13. Kubota Y, Takemoto M, Taniguchi T, Motegi SI, Taniguchi A, Nakagami H, Maezawa Y, Koshizaka M, Kato H, Mori S, Tsukamoto K, Kuzuya M, Yokote K. Management guideline for Werner syndrome 2020. 6. Skin ulcers associated with Werner syndrome: Prevention and non-surgical and surgical treatment. Geriatr Gerontol Int. 2021;21(2):153-9.
14. Motegi SI, Takemoto M, Taniguchi T, Kubota Y, Taniguchi A, Nakagami H, Maezawa Y, Koshizaka M, Kato H, Mori S, Tsukamoto K, Kuzuya M, Yokote K. Management guideline for Werner syndrome 2020. 7. Skin ulcer associated with Werner syndrome dermatological treatment. Geriatr Gerontol Int. 2021;21(2):160-2.
15. Taniguchi A, Tanaka Y, Takemoto M, Kubota Y, Taniguchi T, Motegi SI, Nakagami H, Maezawa Y, Koshizaka M, Kato H, Tsukamoto K, Mori S, Kuzuya M, Yokote K. Management guideline for Werner syndrome 2020. 8. Calcification in tendons associated with Werner syndrome. Geriatr Gerontol Int. 2021;21(2):163-5.
16. Wilding JPH, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I, McGowan BM, Rosenstock J, Tran MTD, Wadden TA, Wharton S, Yokote K, Zeuthen N, Kushner RF; STEP 1 Study Group. Once-weekly semaglutide in adults with overweight or obesity. N Engl J Med. 2021;384(11):989.
17. Araki A, Umegaki H, Sakurai T, Mizuno Y, Miyao M, Imori M, Suzuki S, Cambron-Mellott MJ, Yokote K, Onuma T, Yokono K. Determinants and impact of physical impairment in patient-reported outcomes among older patients with type 2 diabetes mellitus in Japan. Curr Med Res Opin. 2021;37(3):393-402.
18. Kato H, Maezawa Y, Takayama N, Ouchi Y, Kaneko H, Kinoshita D, Takada-Watanabe A, Oshima M, Koshizaka M, Ogata H, Kubota Y, Mitsukawa N, Eto K, Iwama A, Yokote K. Fibroblasts from different body parts exhibit distinct phenotypes in adult progeria Werner syndrome. Aging (Albany NY). 2021;13(4):4946-61.
19. Ishida A, Igarashi K, Ruike Y, Ishiwata K, Naito K, Kono S, Deguchi H, Fujimoto M, Shiga A, Suzuki S, Yoshida T, Tanaka T, Tatsuno I, Yokote K, Koide H. Association of urinary free cortisol with bone formation in patients with mild autonomous cortisol secretion. Clin Endocrinol (Oxf). 2021;94(4):544-50.
20. Takeda K, Ono H, Ishikawa K, Ohno T, Kumagai J, Ochiai H, Matumoto A, Yokoh H, Maezawa Y, Yokote K. Central administration of sodium-glucose cotransporter-2 inhibitors increases food intake involving adenosine monophosphate-activated protein kinase phosphorylation in the lateral hypothalamus in healthy rats. BMJ Open Diabetes Res Care. 2021;9(1):e002104.
21. Kato H, Maezawa Y, Ouchi Y, Takayama N, Sone M, Sone K, Takada-Watanabe A, Tsujimura K, Koshizaka M, Nagasawa S, Saitoh H, Ohtaka M, Nakanishi M, Tahara H, Shimamoto A, Iwama A, Eto K, Yokote K. Generation of disease-specific and CRISPR/Cas9-mediated gene-corrected iPS cells from a patient with adult progeria Werner syndrome. Stem Cell Res. 2021;53:102360.
22. Yokote K, Yamashita S, Arai H, Araki E, Matsushita M, Nojima T, Suganami H, Ishibashi S. Effects of pemafibrate on glucose metabolism markers and liver function tests in patients with hypertriglyceridemia: a pooled analysis of six phase 2 and phase 3 randomized double-blind placebo-controlled clinical trials. Cardiovasc Diabetol. 2021;20(1):96.
23. Kitamoto T, Saegusa R, Tashiro T, Sakurai T, Yokote K, Tokuyama T. Favorable effects of 24-week whole-body vibration on glycemic control and comprehensive diabetes therapy in elderly patients with type 2 diabetes. Diabetes Ther. 2021;12(6):1751-61.
24. Ishiwata K, Suzuki S, Igarashi K, Ruike Y, Naito K, Ishida A, Deguchi-Horiuchi H, Fujimoto M, Koide H, Imamura Y, Sakamoto S, Ichikawa T, Ikeda JI, Yokote K. Characteristics of benign adrenocortical adenomas with 18F-FDG PET accumulation. Eur J Endocrinol. 2021;185(1):155-65.
25. Hiwasa T, Wang H, Goto KI, Mine S, Machida T, Kobayashi E, Yoshida Y, Adachi A, Matsutani T, Sata M, Yamagishi K, Iso H, Sawada N, Tsugane S, Kunimatsu M, Kamitsukasa I, Mori M, Sugimoto K, Uzawa A, Muto M, Kuwabara S, Kobayashi Y, Ohno M, Nishi E, Hattori A, Yamamoto M, Maezawa Y, Kobayashi K, Ishibashi R, Takemoto M, Yokote K, Takizawa H, Kishimoto T, Matsushita K, Kobayashi S, Nomura F, Arasawa T, Kagaya A, Maruyama T, Matsubara H, Tomiita M, Hamanaka S, Imai Y, Nakagawa T, Kato N, Terada J, Matsumura T, Katsumata Y, Naito A, Tanabe N, Sakao S, Tatsumi K, Ito M, Shiratori F, Sumazaki M, Yajima S, Shimada H, Shirouzu M, Yokoyama S, Kudo T, Doi H, Iwase K, Ashino H, Li SY, Kubota M, Tomiyoshi G, Shinmen N, Nakamura R, Kuroda H, Iwadate Y. Serum anti-DIDO1, anti-CPSF2, and anti-FOXJ2 antibodies as predictive risk markers for acute ischemic stroke. BMC Med. 2021;19(1):131.
26. Li SY, Yoshida Y, Kobayashi E, Kubota M, Matsutani T, Mine S, Machida T, Maezawa Y, Takemoto M, Yokote K, Kobayashi Y, Takizawa H, Sata M, Yamagishi K, Iso H, Sawada N, Tsugane S, Kobayashi S, Matsushita K, Nomura F, Matsubara H, Sumazaki M, Ito M, Yajima S, Shimada H, Iwase K, Ashino H, Wang H, Goto K, Tomiyoshi G, Shinmen N, Nakamura R, Kuroda H, Iwadate Y, Hiwasa T. Serum anti-AP3D1 antibodies are risk factors for acute ischemic stroke related with atherosclerosis. Sci Rep. 2021;11(1):13450.
27. Ogura M, Toyoda Y, Sakiyama M, Kawamura Y, Nakayama A, Yamanashi Y, Takada T, Shimizu S, Higashino T, Nakajima M, Naito M, Hishida A, Kawai S, Okada R, Sasaki M, Ayaori M, Suzuki H, Takata K, Ikewaki K, Harada-Shiba M, Shinomiya N, Matsuo H. Increase of serum uric acid levels associated with APOE ε2 haplotype: a clinico-genetic investigation and in vivo approach. Hum Cell. 2021;34(6): 1727-33.
28. Saiki A, Yamaguchi T, Sasaki A, Naitoh T, Matsubara H, Yokote K, Okazumi S, Ugi S, Yamamoto H, Ohta M, Ishigaki Y, Kasama K, Seki Y, Tsujino M, Shirai K, Miyazaki Y, Masaki T, Nagayama D, Tatsuno I. Background characteristics and diabetes remission after laparoscopic sleeve gastrectomy in Japanese patients with type 2 diabetes stratified by BMI: subgroup analysis of J-SMART. Diabetol Int. 2021;12(3):303-12.
29. Ji Q, Ji L, Mu Y, Zhao J, Zinman B, Wanner C, George JT, Zwiener I, Ueki K, Yokote K, Ogawa W, Johansen OE. Effect of empagliflozin on cardiorenal outcomes and mortality according to body mass index: A subgroup analysis of the EMPA-REG OUTCOME trial with a focus on Asia. Diabetes Obes Metab. 2021;23(8):1886-91.
30. Ito M, Hiwasa T, Oshima Y, Yajima S, Suzuki T, Nanami T, Sumazaki M, Shiratori F, Funahashi K, Li SY, Iwadate Y, Yamagata H, Jambaljav B, Takemoto M, Yokote K, Takizawa H, Shimada H. Association of serum anti-PCSK9 antibody levels with favorable postoperative prognosis in esophageal cancer. Front Oncol. 2021;11:708039.
31. Kimura K, Tsukamoto S, Miyazaki K, Kawajiri-Manako C, Ishii A, Rahmutulla B, Fukuyo M, Oshima-Hasegawa N, Mitsukawa S, Takeda Y, Mimura N, Takeuchi M, Ohwada C, Iseki T, Matsusaka K, Sanada M, Yokote K, Kaneda A, Ishida T, Suzuki K, Nakaseko C, Sakaida E. Identification of clonal immunoglobulin λ light-chain gene rearrangements in AL amyloidosis using next-generation sequencing. Exp Hematol. 2021;101-2:34-41.e4.
32. Minamizuka T, Koshizaka M, Shoji M, Yamaga M, Hayashi A, Ide K, Ide S, Kitamoto T, Sakamoto K, Hattori A, Ishikawa T, Kobayashi J, Maezawa Y, Kobayashi K, Takemoto M, Inagaki M, Endo A, Yokote K. Low dose red yeast rice with monacolin K lowers LDL cholesterol and blood pressure in Japanese with mild dyslipidemia: A multicenter, randomized trial. Asia Pac J Clin Nutr. 2021;30(3):424-35.
33. Kobayashi J, Minamizuka T, Koshizaka M, Maezawa Y, Ono H, Yokote K. Serum HDL-C values: An extremely useful marker for differentiating homozygous lipoprotein lipase deficiency from severe hypertriglyceridemia with other causes in Japan: A meta-analysis based on literatures on Japanese homozygous lipoprotein lipase deficiency. Clin Chim Acta. 2021;521:85-89.
34. Yokote K, Suzuki R, Gouda M, Iijima H, Yamazaki A, Inagaki M. Association between glycemic control and cardiovascular events in older Japanese adults with diabetes mellitus: An analysis of the Japanese medical administrative database. J Diabetes Investig. 2021;12(11):2036-45.
35. Ono H, Yokote K. Can we catch the second loach employing BACE1 inhibition, even as the first one might be escaping? J Diabetes Investig. 2021;12(11):1942-3.
36. Kageyama T, Ikeda K, Tanaka S, Taniguchi T, Igari H, Onouchi Y, Kaneda A, Matsushita K, Hanaoka H, Nakada TA, Ohtori S, Yoshino I, Matsubara H, Nakayama T, Yokote K, Nakajima H. Antibody responses to BNT162b2 mRNA COVID-19 vaccine and their predictors among healthcare workers in a tertiary referral hospital in Japan. Clin Microbiol Infect. 2021;27(12):1861.e1-1861.e5.
37. Mishina T, Oshima-Hasegawa N, Tsukamoto S, Fukuyo M, Kageyama H, Muto T, Mimura N, Rahmutulla B, Nagai Y, Kayamori K, Hino Y, Mitsukawa S, Takeda Y, Ohwada C, Takeuchi M, Tsujimura H, Iseki T, Nakaseko C, Ikeda JI, Itami M, Yokote K, Ohara O, Kaneda A, Sakaida E. Genetic subtype classification using a simplified algorithm and mutational characteristics of diffuse large B-cell lymphoma in a Japanese cohort. Br J Haematol. 2021;195(5):731-42.
38. Iso H, Cui R, Takamoto I, Kiyama M, Saito I, Okamura T, Miyamoto Y, Higashiyama A, Kiyohara Y, Ninomiya T, Yamada M, Nakagawa H, Sakurai M, Shimabukuro M, Higa M, Shimamoto K, Saito S, Daimon M, Kayama T, Noda M, Ito S, Yokote K, Ito C, Nakao K, Yamauchi T, Kadowaki T. Risk classification for metabolic syndrome and the incidence of cardiovascular disease in Japan with low prevalence of obesity: a pooled analysis of 10 prospective cohort studies. J Am Heart Assoc. 2021;10(23):e020760.
39. Ogata H, Akita S, Ikehara S, Azuma K, Yamaguchi T, Maimaiti M, Maezawa Y, Kubota Y, Yokote K, Mitsukawa N, Ikehara Y. Calcification in Werner syndrome associated with lymphatic vessels aging. Aging (Albany NY). 2021;13(24):25717-28.
40. Deguchi-Horiuchi H, Koide H, Sakuma I, Gao Y, Higuchi S, Nagano H, Hashimoto N, Horiguchi K, Iwadate Y, Inoshita N, Yokote K, Tanaka T. Two cases of symptomatic secondary hypophysitis due to Rathke's cleft cysts treated with glucocorticoids: long-term follow-up. Endocr J. 2021;68(3):269-79.
41. Naito K, Suzuki S, Ohwada C, Ishiwata K, Ruike Y, Ishida A, Deguchi-Horiuchi H, Fujimoto M, Koide H, Sakaida E, Horiguchi K, Iwadate Y, Tatsuno I, Inoshita N, Ikeda JI, Tanaka T, Yokote K. ICAM1-negative intravascular large B-cell lymphoma of the pituitary gland: a case report and literature review. AACE Clin Case Rep. 2021;7(4):249-55.
42. Sasaki A, Yokote K, Naitoh T, Fujikura J, Hayashi K, Hirota Y, Inagaki N, Ishigaki Y, Kasama K, Kikkawa E, Koyama H, Masuzaki H, Miyatsuka T, Nozaki T, Ogawa W, Ohta M, Okazumi S, Shimabukuro M, Shimomura I, Nishizawa H, Saiki A, Seki Y, Shojima N, Tsujino M, Ugi S, Watada H, Yamauchi T, Yamaguchi T, Ueki K, Kadowaki T, Tatsuno I; Joint Committee in the Japanese Society for Treatment of Obesity, the Japan Diabetes Society, the Japan Society for the Study of Obesity. Metabolic surgery in treatment of obese Japanese patients with type 2 diabetes: a joint consensus statement from the Japanese Society for Treatment of Obesity, the Japan Diabetes Society, and the Japan Society for the Study of Obesity. Diabetol Int 2021;13(1):1-30.
43. Sasaki A, Yokote K, Naitoh T, Fujikura J, Hayashi K, Hirota Y, Inagaki N, Ishigaki Y, Kasama K, Kikkawa E, Koyama H, Masuzaki H, Miyatsuka T, Nozaki T, Ogawa W, Ohta M, Okazumi S, Shimabukuro M, Shimomura I, Nishizawa H, Saiki A, Seki Y, Shojima N, Tsujino M, Ugi S, Watada H, Yamauchi T, Yamaguchi T, Ueki K, Kadowaki T, Tatsuno I; Joint Committee in the Japanese Society for Treatment of Obesity, the Japan Diabetes Society, the Japan Society for the Study of Obesity. Correction to: Metabolic surgery in treatment of obese Japanese patients with type 2 diabetes: a joint consensus statement from the Japanese Society for Treatment of Obesity, the Japan Diabetes Society, and the Japan Society for the Study of Obesity. Diabetol Int 2021;13(1):31-2.
44. Sasaki A, Yokote K, Naitoh T, Fujikura J, Hayashi K, Hirota Y, Inagaki N, Ishigaki Y, Kasama K, Kikkawa E, Koyama H, Masuzaki H, Miyatsuka T, Nozaki T, Ogawa W, Ohta M, Okazumi S, Shimabukuro M, Shimomura I, Nishizawa H, Saiki A, Seki Y, Shojima N, Tsujino M, Ugi S, Watada H, Yamauchi T, Yamaguchi T, Ueki K, Kadowaki T, Tatsuno I; Joint Committee in the Japanese Society for Treatment of Obesity, the Japan Diabetes Society, the Japan Society for the Study of Obesity. Metabolic surgery in treatment of obese Japanese patients with type 2 diabetes: a joint consensus statement from the Japanese Society for Treatment of Obesity, the Japan Diabetes Society, and the Japan Society for the Study of Obesity. Diabetol Int. 2021;13(1):33-4.
45. Tachibana T, Kanda J, Ishizaki T, Najima Y, Tanaka M, Doki N, Fujiwara SI, Kimura SI, Onizuka M, Takahashi S, Saito T, Mori T, Fujisawa S, Sakaida E, Miyazaki T, Aotsuka N, Gotoh M, Watanabe R, Shono K, Usuki K, Tsukada N, Kanamori H, Kanda Y, Okamoto S; Kanto Study Group for Cell Therapy (KSGCT). Clinical benefits of preconditioning intervention in patients with relapsed or refractory acute myelogenous leukemia who underwent allogeneic hematopoietic cell transplantation: A Kanto Study of Group for Cell Therapy Multicenter Analysis. Transplant Cell Ther. 2021;27(1):70.e1-70.e8.
46. Shibamiya A, Ohwada C, Ishii A, Mishina T, Nagai Y, Hino Y, Kayamori K, Oshima-Hasegawa N, Muto T, Tsukamoto S, Takeda Y, Mitsukawa S, Mimura N, Iseki T, Misawa S, Kuwabara S, Nakaseko C, Sakaida E. Successful second autologous stem-cell transplantation for patients with relapsed and refractory POEMS syndrome. Bone Marrow Transplant. 2021;56(2):517-20.
47. Kikuchi T, Mori T, Ohwada C, Onoda M, Shimizu H, Yokoyama H, Onizuka M, Koda Y, Kato J, Takeda Y, Hino Y, Mishina T, Sakaida E, Shono K, Nagao Y, Yokota A, Matsumoto K, Morita K, Okamoto S; Kanto Study Group for Cell Therapy (KSGCT). Pharmacokinetics of intravenous busulfan as condition for hematopoietic stem cell transplantation: comparison between combinations with cyclophosphamide and fludarabine. Int J Hematol. 2021;113(1):128-33.
48. Nakasone H, Kako S, Mori T, Takahashi S, Onizuka M, Fujiwara SI, Sakura T, Sakaida E, Yokota A, Aotsuka N, Hagihara M, Tsukada N, Hatta Y, Usuki K, Watanabe R, Gotoh M, Fujisawa S, Yano S, Kanamori H, Okamoto S, Kanda Y. Stopping tyrosine kinase inhibitors started after allogeneic HCT in patients with Philadelphia chromosome-positive leukemia. Bone Marrow Transplant. 2021;56(6):1402-12.
49. Nakasone H, Kako S, Tachibana T, Tanaka M, Onizuka M, Takahashi S, Yokota A, Fujiwara SI, Sakura T, Sakaida E, Fujisawa S, Yamazaki R, Gotoh M, Hagihara M, Aotsuka N, Tsukada N, Hatta Y, Shimizu H, Usuki K, Watanabe R, Mori T, Yano S, Kanamori H, Kanda Y. Novel indicators of transplant outcomes for PhALL: "current molecular-relapse-free survival". Transplant Cell Ther. 2021;27(9):800.e1-800.
50. Terakura S, Kuwatsuka Y, Sugita J, Takahashi S, Ozawa Y, Ozeki K, Yoshioka S, Nakamae H, Kawakita T, Sawa M, Morishige S, Najima Y, Katsuoka Y, Sakaida E, Kouzai Y, Kimura T, Ichinohe T, Fukuda T, Atsuta Y, Murata M, Teshima T. Effect of methotrexate dose in graft-versus-host disease prophylaxis after single-unit cord blood transplantation in adult acute myeloid leukemia. Int J Hematol. 2021;113(6):840-50.
51. Kurosawa S, Kaito S, Uchida N, Fukuda T, Doki N, Mori T, Hasegawa Y, Takada S, Sakaida E, Tanaka M, Ikegame K, Kanda J, Atsuta Y, Kako S. Allogeneic hematopoietic stem cell transplantation for adult patients with B-cell acute lymphoblastic leukemia with high hyperdiploidy: a retrospective nationwide study. Leuk Lymphoma. 2021;62(10):2514-20.
52. Yasuda S, Aoyama S, Yoshimoto R, Li H, Watanabe D, Akiyama H, Yamamoto K, Fujiwara T, Najima Y, Doki N, Sakaida E, Edahiro Y, Imai M, Araki M, Komatsu N, Miura O, Kawamata N. MPL overexpression induces a high level of mutant-CALR/MPL complex: a novel mechanism of ruxolitinib resistance in myeloproliferative neoplasms with CALR mutations. Int J Hematol. 2021;114(4):424-40.
53. Ishii A, Tsukamoto S, Mishina T, Izumi S, Nagai Y, Yamazaki M, Hino Y, Kayamori K, Oshima-Hasegawa N, Muto T, Mitsukawa S, Takeda Y, Mimura N, Ohwada C, Nakaseko C, Ikeda JI, Sakaida E. Successful allogeneic bone marrow transplantation after massive gastrointestinal bleeding in a patient with myelodysplastic syndrome associated with intestinal Behçet-like disease. Leuk Res Rep. 2021;16:100278.
54. Hino Y, Watanabe A, Seki R, Tsukamoto S, Takeda Y, Sakaida E, Kamei K. A Reference laboratory surveillance on fungal isolates from patients with haematological malignancy in Japan. J Fungi (Basel). 2021;7(10):806.
55. Yasuda T, Sanada M, Kawazu M, Kojima S, Tsuzuki S, Ueno H, Iwamoto E, Iijima-Yamashita Y, Yamada T, Kanamori T, Nishimura R, Kuwatsuka Y, Takada S, Tanaka M, Ota S, Dobashi N, Yamazaki E, Hirose A, Murayama T, Sumi M, Sato S, Tange N, Nakamura Y, Katsuoka Y, Sakaida E, Kawamata T, Iida H, Shiraishi Y, Nannya Y, Ogawa S, Taniwaki M, Asou N, Hatta Y, Kiyoi H, Matsumura I, Horibe K, Mano H, Naoe T, Miyazaki Y, Hayakawa F. Two novel high-risk adult B-cell acute lymphoblastic leukemia subtypes with high expression of CDX2 and IDH1/2 mutations. Blood. 2021 Oct 25: blood.2021011921. Online ahead of print.
56. Tachibana T, Kanda J, Ishizaki T, Najima Y, Tanaka M, Doki N, Fujiwara SI, Kimura SI, Onizuka M, Takahashi S, Saito T, Mori T, Fujisawa S, Sakaida E, Miyazaki T, Aotsuka N, Gotoh M, Watanabe R, Shono K, Kanamori H, Kanda Y, Okamoto S; Kanto Study Group for Cell Therapy (KSGCT). Pre-conditioning intervention in patients with relapsed or refractory acute lymphoblastic leukemia who underwent allogeneic hematopoietic cell transplantation: a KSGCT multicenter retrospective analysis. Ann Hematol. 2021;100(11):2763-71.
57. Kusakabe Y, Chiba T, Oshima M, Koide S, Rizq O, Aoyama K, Ao J, Kaneko T, Kanzaki H, Kanayama K, Maeda T, Saito T, Nakagawa R, Kobayashi K, Kiyono S, Nakamura M, Ogasawara S, Suzuki E, Nakamoto S, Yasui S, Mikata R, Muroyama R, Kanda T, Maruyama H, Kato J, Mimura N, Ma A, Jin J, Zen Y, Otsuka M, Kaneda A, Iwama A, Kato N. EZH1/2 inhibition augments the anti-tumor effects of sorafenib in hepatocellular carcinoma. Sci Rep. 2021;11(1):21396.
58. Shimazu Y, Mizuno S, Fuchida SI, Suzuki K, Tsukada N, Hanagaishi A, Itagaki M, Kataoka K, Kako S, Sakaida E, Yoshioka S, Iida S, Doki N, Oyake T, Ichinohe T, Kanda Y, Astuta Y, Takamatsu H; working group of the Japan Society for Transplantation, Cellular Therapy. Improved survival of multiple myeloma patients treated with autologous transplantation in the modern era of new medicine. Cancer Sci. 2021;112(12):5034-45.
59. Kuroda M, Bujo H, Yokote K, Murano T, Yamaguchi T, Ogura M, Ikewaki K, Koseki M, Takeuchi Y, Nakatsuka A, Hori M, Matsuki K, Miida T, Yokoyama S, Wada J, Harada-Shiba M on behalf of the committee on primary dyslipidemia under the research program on rare and intractable disease of the ministry of health, labour and welfare of Japan. Current status of familial LCAT deficiency in Japan. J Atheroscler Thromb. 2021;28:679-91.

和文

1. 内海尊雄,石井伊都子,小野啓,横手幸太郎 肥満症の薬物治療法-世界の状況とわが国の開発の動向.医学と薬学 2021;78:31-7.
2. 横手幸太郎 社会の中の認知症とフレイル.フレイル対策シリーズ④ 生活習慣病と健康長寿・フレイル対策 2021:124.
3. 石川崇広,横手幸太郎 高齢者と糖尿病.ここが知りたい!糖尿病診療ハンドブック Ver.5 2021:231-8.
4. 横手幸太郎 肥満症.週刊日本医事新報 2021;5058:34-5.
5. 吉本芽生,小出尚史,横手幸太郎 内分泌と救急.治療 2021;103(6):745-50.
6. 中島裕史,猪狩英俊,横手幸太郎 新型コロナワクチンの有効性と安全性の考察.COVID-19有識者会議報告書 https://www.covid19-jma-medical-expert-meeting.jp/topic/6776 2021
7. 横手幸太郎 ウェルナー症候群-ヒトの老化機序解明の鍵を握る遺伝的早老症.SRL宝函 2021;42(2):13-20.
8. 横手幸太郎 あなたの疑問に専門家が回答!健康Q&A 前編 「LDLコレステロールだけ高い」「LDL,中性脂肪...最も注意すべきは?」名医が回答.日経Gooday 2021.
9. 横手幸太郎 あなたの疑問に専門家が回答!健康Q&A 中編 「LDLコレステロールを下げるには?」「糖質と油,どっちを控える?」名医が回答.日経Gooday 2021.
10. 横手幸太郎 あなたの疑問に専門家が回答!健康Q&A 後編 「コレステロールの薬の効果は?」「一生飲まないとダメ?」名医が回答.日経Gooday 2021.
11. 横手幸太郎 脂質異常症の治療Update. 糖尿病合併症 2021;35(1):80-3.
12. 横手幸太郎 特集 早老症研究の最前線 早老症:ヒト老化促進モデルとしての意義をもつ希少難病.日本老年医学会雑誌 2021;58(3):395.
13. 寺本民生,横手幸太郎,荒井秀典 座談会 脂質異常症治療の展望.カレントテラピー 2021;39(9):880-9.
14. 横手幸太郎 特集/生活習慣病 生活習慣病とは.臨牀と研究 2021;98(10):1-3.
15. 前澤善朗 健康特集 動脈硬化はなぜ危ない?. すこやかファミリー 2021;796:6-11.
16. 鈴木佐和子,横手幸太郎 特集 意外と知られていない!? 自科の常識・他科の非常識 第10章:内分泌 副腎偶発腫瘍で発見される褐色細胞腫,18F-FDG PET陽性良性副腎皮質腺腫が増えている. 臨床雑誌内科 2021;128(3):704-6.
17. 石渡一樹, 鈴木佐和子, 横手幸太郎 18F-FDG-PET集積を示す良性副腎皮質腫瘍の病理学的・遺伝子学的特徴. 日本内分泌学会雑誌 2021;97:84-6.
18. 河野聡美, 永野秀和, 村田和貴, 山形一行, 橋本直子, 横山真隆, 井下尚子, 大塚将之, 横手幸太郎, 田中知明 免疫染色scoring, 遺伝子解析を用いた膵神経内分泌腫瘍の特性の検討. 日本内分泌学会雑誌 2021;97:89-91.
19. 横手幸太郎(監修) 最新改訂版 計算いらず コレステロール・中性脂肪対策のおいしいレシピ,学研プラス,東京,2021.
20. 横手幸太郎(監修) 生涯教育シリーズ101 内分泌疾患・糖尿病・代謝疾患-診療のエッセンス-,日本医師会雑誌,日本医師会,東京,2021;150(2).
21. 横手幸太郎(監修) 気をつけよう!血糖値と生活習慣,沢井製薬株式会社,大阪,2021.
22. 横手幸太郎(新聞) 国立大学法人 千葉大学医学部附属病院中央診療棟オープン 横手病院長に聞く 患者に寄り添い質の高い医療を提供. 千葉日報 1月4日, 20面.
23. 横手幸太郎(新聞) 千葉大病院長 緊急メッセージ すでに医療崩壊. 千葉日報 1月13日.
24. 横手幸太郎(新聞) コロナ治療と救急 破綻寸前 千葉大病院長 県民に緊急メッセージ. 産経新聞 1月14日.
25. 横手幸太郎(新聞) コロナ・救急医療「破綻目前」. 朝日新聞 1月14日.
26. 横手幸太郎(新聞) 緊急メッセージ 深刻事態陥りつつある. 読売新聞 1月14日.
27. 猪狩英俊, 横手幸太郎 (新聞) 自宅療養 容体急変や死亡例. 千葉日報 1月17日.
28. 横手幸太郎(新聞) 千葉大医学部附属病院 コロナも急患も対応困難 「医療破綻 命を救えなくなる」. 東京新聞 1月18日.
29. 横手幸太郎(新聞) 救える命 救えぬ危機 コロナと救急医療の両立「困難に」. 毎日新聞 1月18日.
30. 横手幸太郎(新聞) 年頭所感. 東海・関東医事新報社 第680号2面, 1月20日.
31. 横手幸太郎,早老症研究班(新聞) 診療指針 世界へ発信 ウェルナー症候群.河北新報 2月5日.
32. 横手幸太郎,早老症研究班(新聞) 早老症の診療指針 公表. 東京新聞 2月10日.
33. 横手幸太郎(新聞) 千葉大病院ワクチンセンター視察. 千葉日報 2月26日.
34. 横手幸太郎(新聞) 安全接種へ独自研究 千葉大病院ワクチンセンター公開. 東京新聞 2月26日.
35. 横手幸太郎(新聞) 千葉大病院 ワクチンセンター開設. 読売新聞 2月26日.
36. 横手幸太郎(新聞) ワクチン研究のセンターを視察 千葉大病院で知事. 毎日新聞 2月26日.
37. 堺田惠美子 初発慢性骨髄性白血病の治療戦略. 臨床血液, 日本血液学会 教育講演特別号 2021;62(8):1012-23.
38. 堺田惠美子 [IV] 白血球系疾患 2.リンパ系 15) POEMS症候群. 専門医のための血液病学. 医学書院 2021
39. 石井改, 塚本祥吉, 堺田惠美子  7.ASH meeting report 2) 急性白血病.腫瘍内科 2021
40. 一色佑介, 三村尚也, 塚本祥吉, 堺田惠美子, 中世古知昭 POEMS症候群に特徴的な免疫グロブリン軽鎖変異パターン. 血液内科 2021;82(5):684-9.
41. 鎌田百合,大島渚,堺田惠美子 POEMS症候群の診断と治療. 血液内科 2021;83(2):282-8.
42. 堺田惠美子 悪性腫瘍の病態と治療 SBO 105 悪性腫瘍の治療における薬物治療の位置づけ. 日本薬学会スタンダード薬学シリーズ 総監修 市川厚 第6巻 薬と疾病 Ⅲ. 薬物治療(2)および薬物治療に役だつ情報 第3版, 東京化学同人 2021年改訂