Graduate School of Medicine, Chiba University

Department of Emergency and Critical Care Medicine

Chiba University Hospital

Department of Emergency and Critical Care Medicine

Welcome to the Department of Emergency and Critical Care Medicine,
Chiba University Graduate School of Medicine

Message from the Chairman

Welcome to the Department of Emergency Medicine and Critical Care Medicine of Chiba University Graduate School of Medicine/Chiba University Hospital website.

We provide seamless care in emergency and intensive care, from pre-hospital emergency care (both by ground and air ambulances) to advanced medical/surgical treatment in the ER, followed by multidisciplinary care in the ICU. Physicians from various countries have belonged to our department, not only to observe but to actually work in practice under the clinical training licensure from the Japanese government, in an open environment with proactive teamwork.

We are also passionate in advanced medical/scientific research. Our major research topics include sepsis, ECMO, vascular permeability, the development of artificial adjuvant therapy, the development of ICT systems and biometric devices to solve problems in emergency/disaster medicine. Furthermore, we work on the development of AI-based prediction algorithms and supporting tools for diagnostic imaging.

We welcome anyone and everyone who would like to join our practice.

Professor and Chairman
Taka-aki Nakada, Department of Emergency and Intensive Care Medicine, Chiba University

Facilities and activities

Facility

Emergency room (ER) 8000 patients/year
Intensive Care Units (ICU) 26 beds, 2000 patients/year

Member

Faculty 13
Fellow 6
Resident 12
Graduate student 5
Research technician 2

Publication

2024

Ikezawa N, Okamoto T, Yoshida Y, Kurihara S, Takahashi N, Nakada TA, Haneishi H. Toward an application of automatic evaluation system for central facial palsy using two simple evaluation indices in emergency medicine. Scientific reports 2024; 14: 3429.

Oami T, Abnam S, Shimazui T, Chen CW, Sweat YY, Liang Z, Burd EM, Farris AB, Roland JT, Tsukita S, Ford ML, Turner JR, Coopersmith CM. Claudin-2 upregulation enhances intestinal permeability, immune activation, dysbiosis, and mortality in sepsis. Proceedings of the National Academy of Sciences of the United States of America 2024; 121: e2217877121.

Abe T, Iriyama H, Imaeda T, Komori A, Oami T, Aizume T, Takahashi N, Yamao Y, Nakagawa S, Ogura H, Umemura Y, Matsushima A, Fushimi K, Shime N, Nakada TA. Epidemiology and patterns of empiric antimicrobial therapy practice in patients with community-onset sepsis using data from a Japanese nationwide medical claims database-the Japan Sepsis Alliance (JaSA) study group. IJID regions 2024; 10: 162-167.

Abe R, Shimazui T, Sugo M, Ogawa A, Namekawa M, Kitamura N, Kido S. Achievement of adequate nutrition contributes to maintaining the skeletal muscle area in patients with sepsis undergoing early mobilization: a retrospective observational studypsis undergoing early mobilization: a retrospective observational study. BMC nutrition 2024; 10: 32.

Yamao Y, Oami T, Yamabe J, Takahashi N, Nakada TA. Machine-learning model for predicting oliguria in critically ill patients. Scientific reports 2024; 14: 1054.

Oami T, Abe T, Nakada TA, Imaeda T, Aizimu T, Takahashi N, Yamao Y, Nakagawa S, Ogura H, Shime N, Umemura Y, Matsushima A, Fushimi K. Association between hospital spending and in-hospital mortality of patients with sepsis based on a Japanese nationwide medical claims database study. Heliyon 2024; 10: e23480.

Kikutani K, Nishikimi M, Matsui K, Sakurai A, Hayashida K, Kitamura N, Tagami T, Nakada TA, Matsui S, Ohshimo S, Shime N ; SOS-KANTO 2017 Study Group. Prediction of the neurological outcomes post-cardiac arrest: A prospective validation of the CAST and rCAST. The American journal of emergency medicine 2024; 75: 46-52.

2023

Shinozaki M, Nakada TA, Saito D, Tomita K, Nomura Y, Nakaguchi T. Cut-off value of capillary refill time for peripheral circulatory failure diagnosis. Prehospital and disaster medicine 2023; 38:319-325

Oami T, Okada Y, Sakuraya M, Fukuda T, Shime N, Nakada TA. Efficiency and workload reduction of semi-automated citation screening software for creating clinical practice guidelines: a prospective observational study. Journal of epidemiology. 2023 Dec 16.doi: 10.2188/jea.JE20230227. Online ahead of print.

Shimoyama K, Endo A, Shimazui T, Tagami T, Yamakawa K, Hayakawa M, Ogura T, Hirayama A, Yasunaga H, Oda J. Association between obesity and mortality in critically ill COVID-19 patients requiring invasive mechanical ventilation: a multicenter retrospective observational study. Scientific reports 2023; 13: 11961.

Chihade DB, Smith P, Swift DA, Otani S, Zhang W, Chen CW, Jeffers LA, Liang Z, Shimazui T, Burd EM, Farris AB, Staitieh BS, Guidot DM, Ford ML, Koval M, Coopersmith CM. Myosin light chain kinase deletion worksens lung permeability and increases mortality in pneumonia-induced sepsis. Shock 2023; 59: 612-620.

Takahashi N, Kondo Y, Kubo K, Egi M, Ohshima Y, Nakada TA. Efficacy of therapeutic drug monitoring-based antibiotic regimen in critically ill patients: a systematic review and meta-analysis of randomized controlled trials. Journal of intensive care 2023; 11: 48.

Nishikimi M, Ohshimo S, Hamaguchi J, Fujizuka K, Hagiwara Y, Anzai T, Ishii J, Ogata Y, Aokage T, Ikeda T, Yagi T, Suzuki G, Ishikura K, Katsuta K, Konno D, Hattori N, Nakamura T, Matsumura Y, Kasugai D, Kikuchi H, Iino T, Kai S, Hashimoto H, Yoshida T, Igarashi Y, Ogura T, Matsumura K, Shimizu K, Nakamura M, Ichiba S, Takahashi K, Shime N. High versus low positive end-expiratory pressure setting in patients receiving veno-venous extracorporeal membrane oxygenation support for severe acute respiratory distress syndrome: study protocol for the multicentre, randomised ExPress SAVER Trial. BMJ open 2023; 13: e072680.

Oami T, Yumoto T, Shimazui T, Sarmiento S, Klingensmith NJ, Chen CW, Otani S, Liang Z, Burd EM, Mahdi ZK, Ford ML, Coopersmith CM. Chronic ethanol use worsens gut permeability and alters tight junction expression in a murine sepsis model. Shock 2023; 60: 280-290.

Imaeda T, Oami T, Takahashi N, Saito D, Higashi A, Nakada TA. Epidemiology of sepsis in a Japanese administrative database. Acute medicine & surgery 2023; 10: e890.

Hayashi Y, Shimazui T, Tomita K, Shimada T, Miura RE, Nakada TA. Associations between fluid overload and outcomes in critically ill patients with acute kidney injury: a retrospective observational study. Scientific reports 2023; 13: 17410.

Inoue H, Oya M, Aizawa M, Wagatsuma K, Kamimae M, Kashiwagi Y, Ishii M, Wakabayashi H, Fujii T, Suzuki S, Hattori N, Tatsumoto N, Kawakami E, Asanuma K. Predicting dry weight change in Hemodialysis patients using machine learning. BMC nephrology 2023; 24: 196.

Hirama R, Takeda K, Sakao S, Kasai H, Miyata S, Shikano K, Naito A, abe M, Kawasaki T, Shigeta A, Nakada TA, Igari H, Suzuki T. A Comparison of Clinical Presentations in Coronavirus disease 2019 caused by different Omicron variants in Japan: a retrospective study. Internal Medicine 2023; 62: 2321-2328.

Shimada-Sammori K, Shimada T, Miura R, Kawaguchi R, Yamao Y, Oshima T, Tomita K, Shinozaki K, Nakada TA. Machine learning algorithms for predicting days of high incidence for out-of-hospital cardiac arrest. Scientific reports 2023; 13: 9950.

Yoshida Y, Hayashi Y, Shimada T, Hattori N, Tomita K, Miura RE, Yamao Y, Tateishi S, Iwadate Y, Nakada TA. Prehospital stroke-scale machine-learning model predicts the need for surgical intervention. Scientific reports 2023; 13: 9135.

Yamao Y, Oami T, Kawakami E, Nakada TA. Protocol to acquire time series data on adverse reactions following vaccination using a smartphone or web-based platform. STAR protocols 2023; 4: 102284.

Komaru Y, Sadahiro T, Nakada TA, Hattori N, Moriguchi T, Goto J, Shiga H, Kikuchi Y, Negi S, Shigematsu T, Kuriyama N, Nakamura T, Doi K. Urinary neutrophil gelatinase-associated lipocalin and plasma IL-6 in discontinuation of continuous venovenous hemodiafiltration for severe acute kidney injury: a multicenter prospective observational study. Annals of intensive care 2023; 13: 42.

Kakisaka K, Nakayama N, Kumagai K, Hisanaga T, Kondo T, Setsu T, Sato S, Kooka Y, Endo K, Yoshida Y, Oikawa T, Kuroda H, Abe R, Nakada TA, Ikura Y, Harada Kenichi, Genda T, Terui S, Kato N, Takami T, Ido A, Mochida S, Matsumoto T, Tanaka A. Distinction of drug-induced liver injury from autoimmune hepatitis in patients with acute liver injury: Proposal of a combination of diagnostic scores. Gastro Hep Advances 2023; 2: 497-504.

Kuroiwa R, Tateishi Y, Oshima T, Shibuya K, Inagaki T, Murata A, Kuwabara S. Cardiovascular autonomic dysfunction induced by mechanical insufflation-exsufflation in Guillain-Barré syndrome. Respirology case reports 2023; 11: e01135.

Niibe Y, Suzuki T, Yamazaki S, Suzuki T, Hattori N, Nakada TA, Ishii I. Pharmacokinetics of vancomycin and meropenem during continuous online hemodiafiltration: A case report. Journal of global antimicrobial resistance 2023; 33: 31-34.

Fujiwara K, Yasui S, Kondo T, Nakamura M, Arai M, Kanda T, Yokosuka O, Ohtsuka M, Abe R, Kato N. Thirty-two years' experience of treating fulminant hepatitis in a Japanese single center. Hepatology research 2023; 53: 357-369.

Oami T, Nakada TA, Abe T, Takahashi N, Yamao Y, Nakagawa S, Ogura H, Shime N, Umemura Y, Matsushima A, Fushimi K. Mortality analysis among sepsis patients in and out of intensive care units using the Japanese nationwide medical claims database: a study by the Japan Sepsis Alliance study group. Journal of intensive care 2023; 11: 2

Uehara K, Tagami T, Hyodo H, Ohara T, Sakurai A, Nakada TA, Takeda M, Yokota H, Yasutaka M. Prehospital ABC (Age, Bystander and Cardiogram) scoring system to predict neurological outcomes of cardiopulmonary arrest on arrival: post hoc analysis of a multicentre prospective observational study. Emergency medicine journal 2023; 40: 42-47.

2022

Shimazui T, Kitamura N, Kako K, Iwase S, Suzuki T, Hoshino S, Futagami H, Kibayashi K, Nakao K. High-flow continuous hemodiafiltration successfully decreased blood pregabalin levels in a patient with severe pregabalin intoxication: a case report. Renal Replacement Therapy 2022; 8: 60.

Namkoong H, Edahiro R, Nishihara H, Sonehara K, Tanaka H, Azekawa S, Mikami Y, Lee H, Hasegawa T, Okudela K, Motooka D, kanai M, Naito T, Yamamoto K, Wang QS, Saiki R, Ishihara R, Matsubara R, Hamamoto J, hayashi J, Yoshimura Y, tachikawa N, Yanagita N, Hyugaji E, Shimizu E, Katayama E, Kato K, Morita Y, Takahashi T, Harada N, Naito T, Hiki M, Matsushita Y, Tagami H, Aoki R, Nakamura R, Harada S, Sasano H, kabata H, Masaki K, Kamata H, Ikemura S, Chubachi S, Terai H, Morita A, Asakura T, Sasaki J, Morisaki H, Uwamino Y, Nanki K, Uchida S, Okamori S, Terai H, Morita A, Asakura T, Shibata S, Matsui Y, Hosoda C, Takano K, Nishida T, Kobayashi Y, Takaku Y, Takayanagi N, Ueda S, Tada A, Miyawaki M, Yamamoto M, Yoshida E, Hayashi R, Nagasaka T, Arai S, Kaneko Y, Sasaki K, Tagaya E, Kawana M, Arimura K, Takahashi K, Anzai T, Ito S, Endo A, Uchimura Y, Miyazaki Y, Honda T, Tateishi T, Tohda S, Ichimura S, Sonobe K, Sassa CT, Nakajima J, Nakano Y, Anan R, Arai R, Kurihara Y, Harada Y, Nishio K, Ueda T, Azuma M, Saito R, Sado T, Miyazaki Y, Sato R, Nagasaki T, Yasui Y, Hasegawa Y, Mutoh Y, Kimura T, Sato T, Takei R, Hagimoto S, Noguchi Y, Yamano Y, Sasano H, Ota S, Nakamori Y, Yoshiya K, Saito F, Yoshihara T, Wada D, IwamurIwamura H, Kanayama S, Maruyama S, Yoshiyama T, Ohta K, Kokuto H, Ogata H, Tanaka Y, Arakawa K, Shimoda M, Osawa T, Tateno H, Hase I, Yoshida S, Suzuki S, Kawada M, Horinouchi H, Saito F, Mitamura K, Hagihara M, Ochi J, Uchida T, Baba R, Arai D, Ogura T, Takahashi H, Hagiwara S, Nagao G, Konishi S, Nakachi I, Murakami K, Yamada M, Sugiura H, Sano H, Matsumoto S, Kimura N, Ono Y, Baba H, Suzuki Y, Nakayama S, Masuzawa K, Namba S, Suzuki K, Naito Y, Liu YC, Takuwa A, Sugihara F, Wing JB, Sakakibara S, Hizawa N, Shiroyama T, Miyawaki S, Kawamura Y, Nakayama A, Matsuo H, Maeda Y, Nii T, Noda Y, Niitsu T, Adachi Y, Enomoto T, Amiya S, Hara R, Yamaguchi Y, Murakami T, Kuge T, Matsumoto K, Yamamoto Y, Yamamoto M, Yoneda M, Kishikawa T, Yamada S, Kawabata S, Kijima N, Takagaki M, Sasa N, Ueno Y, Suzuki M, Takemoto N, Eguchi H, Fukusumi T, Imai T, Fukushima M, Kishima H, Inohara H, Tomono K, Kato K, Takahashi M, Matsuda F, Hirata H, Takeda Y, Koh H, Manabe T, Funatsu Y, Ito F, Fukui T, Shinozuka K, Kohashi S, Miyazaki M, Shoko T, Kojima M, Adachi T, Ishikawa M, Takahashi K, Inoue T, Hirano T, Kobayashi K, Takaoka H, Watanabe K, Miyazawa N, Kimura Y, Sado R, Sugimoto H, Kamiya A, Kuwahara N, Fujiwara A, Matsunaga T, Sato Y, Okada T, Hirai Y, Kawashima H, Narita A, Niwa K, Sekikawa Y, Nishi K, Nishitsuji M, Tani M, Suzuki J, Nakatsumi H, Ogura T, Kitamura H, Hagiwara E, Murohashi K, Okabayashi H, Mochimaru T, Nukaga S, Satomi R, Oyamada Y, Mori N, Baba T, Fukui Y, Odate M, Mashimo S, Makino Y, Yagi K, Hashiguchi M, Kagyo J, Shiomi T, Fuke S, Saito H, Tsuchida T, Fujitani S, Takita M, Morikawa D, Yoshida T, Izumo T, Inomata M, Kuse N, Awano N, Tone M, Ito A, Nakamura Y, Hoshino K, Maruyama J, Ishikura H, Takata T, Odani T, Amishima M, Hattori T, Shichinohe Y, Kagaya T, Kita T, Ohta K, Sakagami S, Koshida K, Hayashi K, Shimizu T, Kozu Y, Hiranuma H, Gon Y, Izumi N, Nagata K, Ueda K, Taki R, Hanada S, Kawamura K, Ichikado K, Nishiyama K, Muranaka H, Nakamura K, Hashimoto N, Wakahara K, Sakamoto K, Omote N, Ando A, Kodama N, Kaneyama Y, Maeda S, Kuraki T, Matsumoto T, Yokote K, Nakada TA, Abe R, Oshima T, Shimada T, Harada M, Takahashi T, Ono H, Sakurai T, Shibusawa T, Kimizuka Y, Kawana A, Sano T, Watanabe C, Suematsu R, Sageshima H, Yoshifuji A, Ito K, Takahashi S, Ishioka K, Nakamura M, Masuda M, Wakabayashi A, Watanabe H, Ueda S, Nishikawa M, Chihara Y, Takeuchi M, Onoi K, Shinozuka J, Sueyoshi A, Nagasaki Y, Okamoto M, Ishihara S, Shimo M, Tokunaga Y, Kusaka Y, Ohba T, Isogai S, Ogawa A, Inoue T, Fukuyama S, Eriguchi Y, Yonekawa A, Kan-O K, Matsumoto K, Kanaoka K, Ihara S, Komuta K, Inoue Y, Chiba S, Yamagata K, Hiramatsu Y, Kai H, Asano K, Oguma T, Ito Y, Hashimoto S, Yamasaki M, Kasamatsu Y, Komase Y, Hida N, Tsuburai T, Oyama B, Takada M, Kanda H, Kitagawa Y, Fukuta T, Miyake T, Yoshida S, Ogura S, Abe S, Kono Y, Togashi Y, Takoi H, Kikuchi R, Ogawa S, Ogata T, Ishihara S, Kanehiro A, Ozaki S, Fuchimoto Y, Wada S, Fujimoto N, Nishiyama K, Terashima M, Beppu S, Yoshida K, Narumoto O, Nagai H, Ooshima N, Motegi M, Umeda A, Miyagawa K, Shimada H, Endo M, Ohira Y, Watanabe M, Inoue S, Igarashi A, Sato M, Sagara H, Tanaka A, Ohta S, Kimura T, Shibata Y, Tanino Y, Nikaido T, Minemura H, Sato Y, Yamada Y, Hashino T, Shinoki M, Iwagoe H, Takahashi H, Fujii K, Kishi H, Kanai M, Imamura T, Yamashita T, Yatomi M, Maeno T, Hayashi S, Takahashi M, Kuramochi M, Kamimaki I, Tominaga Y, Ishii T, Utsugi M, Ono A, Tanaka T, Kashiwada T, Fujita K, Saito Y, Seike M, Watanabe H, Matsuse H, Kodaka N, Nakano C, Oshio T, Hirouchi T, Makino S, Egi M; Biobank Japan Project; Omae Y, Nannya Y, Ueno T, Katayama K, Ai M, Fukui Y, Kumanogoh A, Sato T, Hasegawa N, Tokunaga K, Ishii M, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Okada Y. DOCK2 is involved in the host genetics and biology of severe COVID-19. Nature 2022; 609: 754-760.

Wang QS, Edahiro R, Namkoong H, Hasegawa T, Shirai Y, Sonehara K, Tanaka H, Lee H, Saiki R, Hyugaji T, Shimizu E, Katayama K, Kanai M, Naito T, Sasa N, Yamamoto K, Kato Y, Morita T, Takahashi K, Harada N, Naito T, Hiki M, Matsushita Y, Takagi H, Ichikawa M, Nakamura A, Harada S, Sandhu Y, Kabata H, Masaki K, Kamata H, Ikemura S, Chubachi S, Okamori S, Terai H, Morita A, Asakura T, Sasaki J, Morisaki H, Uwamino Y, Nanki K, Uchida S, Uno S, Nishimura T, Ishiguro T, Isono T, Shibata S, Matsui Y, Hosoda C, Takano K, Nishida T, Kobayashi Y, Takaku Y, Takayanagi N, Ueda S, Tada A, Miyawaki M, Yamamoto M, Yoshida E, Hayashi R, Nagasaka T, Arai S, Kaneko Y, Sasaki K, Tagaya E, Kawana M, Arimura K, Takahashi K, Anzai T, Ito S, Endo A, Uchimura Y, Miyazaki Y, Honda T, Tateishi T, Tohda S, Ichimura N, Sonobe K, Sassa CT, Najima J, Nakano Y, Nakajima Y, Anan R, Arai R, Kurihara Y, Harada Y, Nishio K, Azuma M, Saito R, Sado T, Miyazaki Y, Sato R, Haruta Y, Nagasaki T, Yasui Y, Hasegawa Y, Mutoh Y, Kimura T, sato T, Takei R, Hagimoto S, Yamano Y, Sasano H, Ota S, Nakamori Y, Yoshiya K, Saito F, Yoshihara T, Wada D, Iwamura H, Kanayama S, Mayuyama S, Yoshiyama T, Ohta K, Kokuto H, Ogata H, Tanaka Y, Arakawa K, Shimoda M, Osawa T, Tateno H, Hase I, Yoshida S, Suzuki S, Kawada M, Horinoudhi H, Saito F, Mitamura K,HagiharHagihara M, Ochi J, Uchida T, Baba R, Arai D, Ogura T, Takahashi H, Hagiwara S, Nagao G, Konishi S, Nakachi I, Murakami K, Yamada M, Sugiura H, Sano H, Matsumoto S, Kimura N, Ono Y, Baba H, Suzuki Y, Nakayama S, Masuzawa K, Namba S, Shiroyama T, Noda Y, Niitsu T, Adachi Y, Enomoto T, Amiya S, Hara R, Yamaguchi Y, Murakami T, Kuge T, Matsumoto K, Yamamoto Y, Yamamoto M, Yoneda M, Tomono K, Kato K, Hirata H, Takeda Y, Koh H, Manabe T, Funatsu Y, Ito F, Fukui T, Shinozuka K, Kohashi S, Miyazaki M, Shoko T, Kojima M, Adachi T, Ishikawa M, Takahashi K, Inoue T, Hirano T, Kobayashi K, Takaoka H, Watanabe K, Miyazawa N, Kimura Y, Sado R, Sugimoto H, Kamiya A, Kuwahara N, Fujiwara A, Matsunaga T, Sato Y, Okada T, Hirai Y, Kawashima H, Narita A, Niwa K, Sekikawa Y, Nishi K, Nishitsuji M, Tani M, Suzuki J, Nakatsumi H, Ogura T, Kitamura H, Hagiwara E, Murohashi K, Okabayashi H, Mochimaru T, Nukaga S, Satomi R, Oyamada Y, Mori N, Baba T, Fukui Y, Odate M, Mashimo S, Makino Y, Yagi K, Hashiguchi M, Kagyo J, Shiomi T, Fuke S, Saito H, Tsuchida T, Fujitani S, Takita M, Morikawa D, Yoshida T, Izumo T, Inomata M, Kuse N, Awano N, Tone M, Ito A, Nakamura Y, Hoshino K, Maruyama J, Ishikura H, Takata T, Odani T, Amishima M, Hattori T, Shichinohe Y, Kagaya T, Kita T, Ohta K, Sakagami S, Koshida K, Hayashi K, Shimizu T, Kozu Y, Hiranuma H, Gon Y, Izumi N, Nagata K, Ueda K, Taki R, Hanada S, Kawamura K, Ichikado K, Nishiyama K, Muranaka H, Nakamura K, Hashimoto N, Wakahara K, Koji S, Omote N, Ando A, Kodama N, Kaneyama Y, Maeda S, Kuraki T, Matsumoto T, Yokote K, Nakada TA, Abe R, Oshima T, Shimada T, Harada M, Takahashi T, Ono H, Sakurai T, Shibusawa T, Kimizuka Y, Kawana A, Sano T, Watanabe C, Suematsu R, Sageshima H, Yoshifuji A, Ito K, Takahashi S, Ishioka K, Nakamura M, Masuda M, Wakabayashi A, Watanabe H, Ueda S, Nishikawa M, Chihara Y, Takeuchi M, Onoi K, Shinozuka J, Sueyoshi A, Nagasaki Y, Okamoto M, Ishihara S, Shimo M, Tokunaga Y, Kusaka Y, Ohba T, Isogai S, Ogawa A, Inoue T, Fukuyama S, Eriguchi Y, Yonekawa A, Kan-O K, Matsumoto K, Kanaoka K, Ihara S, Komuta K, Inoue Y, Chiba S, Yamagata K, Hiramatsu Y, Kai H, Asano K, Oguma T, Ito Y, Hashimoto S, Yamasaki M, Kasamatsu Y, Komase Y, Hida N, Tsuburai T, Oyama B, Takada M, Kanda H, Kitagawa Y, Fukuta T, Miyake T, Yoshida S, Ogura S, Abe S, Kono Y, Togashi Y, Takoi H, Kikuchi R, Ogawa S, Ogata T, Ishihara S, Kanehiro A, Ozaki S, Fuchimoto Y, Wada S, Fujimoto N, Nishiyama K, Terashima M, Beppu S, Yoshida K, Narumoto O, Nagai H, Ooshima N, Motegi M, Umeda A, Miyagawa K, Shimada H, Endo M, Ohira Y, Watanabe M, Inoue S, Igarashi A, Sato M, Sagara H, Tanaka A, Ohta S, Kimura T, Shibata Y, Tanino Y, Nikaido T, Minemura H, Sato Y, Yamada Y, Hashino T, Shinoki M, Iwagoe H, Takahashi H, Fujii K, Kishi H, Kanai M, Imamura T, Yamashita T, Yatomi M, Maeno T, Hayashi S, Takahashi M, Kuramochi M, Kamimaki I, Tominaga Y, Ishii T, Utsugi M, Ono A, Tanaka T, Kashiwada T, Fujita K, Saito Y, Seike M, Watanabe H, Matsuse H, Kodaka N, Nakano C, Oshio T, Hirouchi T, Makino S, Egi M, Omae Y, Nannya Y, Ueno T, Takano T, Katayama K, Ai M, Kumanogoh A, Sato T, Hasegawa N, Tokunaga K, Ishii M, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Okada Y. The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force. Nature communications 2022; 13: 4830

Matsumura Y, Higashi A, Izawa Y, Hishikawa S. Organ perfusion during partial REBOA in haemorrhagic shock: dynamic 4D-CT analyses in swine. Scientific reports 2022; 12: 18745.

Ye C, Kawasaki M, Nakano K, Ohnishi T, Watanabe E, Oda S, Nakada TA, Haneishi H. Acquisition and Analysis of Microcirculation Image in Septic Model Rats. Sensors 2022; 22: 8471.

Abe M, Shiga H, Tatsumi H, Endo Y, Kikuchi Y, Suzuki Y, Doi K, Nakada TA, Nagafuchi H, Hattori N, Hirohashi N, Moriguchi T, Yamaga O, Nishida O. Results of the 2018 Japan Society for Blood Purification in Critical Care survey: current status and outcomes. Renal replacement therapy 2022; 8: 58.

Kawaguchi R, Nakada TA, Hattori N, Tomita K, Saito D, Shinozaki M, Nakaguchi T. Intravascular fluid also affects results: No prolongation of capillary refill time by removal of excessive fluids by hemodialysis. The American journal of emergency medicine 2022; 60: 187-188.

Takahashi N, Imaeda T, Nakada TA, Oami T, Abe T, Yamao Y, Nakagawa S, Ogura H, Shime N, Matsushima A, Fushimi K. Short- versus long-course antibiotic therapy for sepsis: a post hoc analysis of the nationwide cohort study. Journal of intensive care 2022; 10: 49.

Ikeda K, Nakada TA, Kageyama T, Tanaka S, Yoshida N, Ishikawa T, Goshima Y, Otaki N, Iwami S, Shimamura T, Taniguchi T, Igari H, Hanaoka H, Yokote K, Tsuyuzaki K, Nakajima H. Detecting time-evolving phenotypic components of adverse reactions against BNT162b2 SARS-CoV-2 vaccine via non-negative tensor factorization. iScience 2022; 25: 105237.

Seno S, Naruhashi T, Kitamura R, Matsumura Y. Techniques for performing resuscitative endovascular balloon occlusion of the aorta. Journal of Endovascular Resuscitation and Trauma Management 2022; 60: 41-49.

Nagashima F, Irahara T, Ishida K, Maruhashi T, Matsumura Y. Resuscitative Thoracotomy and Aortic Cross-Clamp and Resuscitative Endovascular Balloon Occlusion of the Aorta. Endovascular Resuscitation and Trauma Management 2022; 60: 19-26.

Matsumura Y, Shinozuka K. Endovascular strategy in obstetrics. Journal of Endovascular Resuscitation and Trauma Management 2022; 60: 67-71.

Matsumoto S, Nakanishi R, Ichibayashi R, Honda M, Hayashida K, Sakurai A, Kitamura N, Tagami T, Nakada TA, Takeda M, Ikeda T, SOS-KATO Study. Heart Rate and Mortality After Resuscitation in Patients With Out-of-Hospital Cardiac Arrest - Insights From the SOS-KANTO Registry. Circulation journal 2022; 86: 1562-1571.

Takeda M, Oami T, Hayashi Y, Shimada T, Tateishi Y, Miura RE, Yamao Y, Abe R, Kobayashi Y, Nakada TA. Prehospital diagnostic algorithm for acute coronary syndrome using machine learning: a prospective observational study. Scientific reports 2022; 12: 14593.

Gando S, Shiraishi A, Wada T, Yamakawa K, Fujishima S, Saitoh D, Kushimoto S, Ogura H, Abe T, Mayumi T, Sasaki J, Kotani J, Takeyama N, Tsuruta R, Takuma K, Shiraishi S, Shiino Y, Nakada TA, Okamoto K, Sakamoto Y, Hagiwara A, Fujimi S, Umemura Y, Otomo Y, JAAM FORECAST. Effects of tranexamic acid on coagulofibrinolytic markers during the early stage of severe trauma: A propensity score-matched analysis. Medicine 2022; 101: e29711.

Ono R, Iwahana T, Kato H, Hattori N, Kobayashi Y. Successful weight reduction of over 70 kg under hemodialysis and renal function recovery after 87 days of anuria in a patient with dilated cardiomyopathy. Journal of cardiology cases 2022; 26: 9-12.

Saito D, Nakada TA, Imaeda T, Takahashi N, Shinozaki M, Shimizu R, Nakaguchi T. Impact of posture on capillary refilling time. The American journal of emergency medicine 2022; 56: 378-379.

Karasawa S, Nakada TA, Sato M, Miyasho T, Shimada T, Oshima T, Suda K, Shinozaki K, Oda S. Early elevation of cell-free DNA after acute mesenteric ischemia in rats. The Journal of surgical research 2022; 269: 28-35.

Iwase S, Nakada TA, Shimada T, Oami T, Shimazui T, Takahashi N, Yamabe J, Yamao Y, Kawakami E. Prediction algorithm for ICU mortality and length of stay using machine learning. Scientific reports 2022; 12: 12912.

Iwamura C, Hirahara K, Kiuchi M, Ikehara S, Azuma K, Shimada T, Kuriyama S, Ohki S, Yamamoto E, Inaba Y, Shiko Y, Aoki A, Kokubo K, Hirasawa R, Hishiya T, Tsuji K, Nagaoka T, Ishikawa S, Kojima A, Mito H, Hase R, Kasahara Y, Kuriyama N, Tsukamoto T, Nakamura S, Urushibara H, Kaneda S, Sakao S, Tobiume M, Suzuki Y, Tsujiwaki M, Kubo T, Hasegawa T, Nakase H, Nishida O, Takahashi K, Baba K, Izumi Y, Okazaki T, Kimura NK, Yoshino I, Igari H, Nakajima H, Suzuki T, Hanaoka H, Nakada TA, Ikehara Y, Yokote K, Nakayama T. Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2-induced lung exudative vasculitis and predicts COVID-19 severity. Proceedings of the National Academy of Sciences of the United States of America 2022; 119: e2203437119.

Mochida S, Nakayama N, Terai S, Yoshiji H, Shimizu M, Ido A, Inoue K, Genda T, Takikawa Y, Takami T, Kato N, Abe M, Abe R, Inui A, Ohira H, Kasahara M, Chayama K, Hasegawa K, Tanaka A. Diagnostic criteria for acute-on-chronic liver failure and related disease conditions in Japan. Hepatology research 2022; 52: 417-421.

Oami T, Imaeda T, Nakada TA, Abe T, Takahashi N, Yamao Y, Nakagawa S, Ogura H, Shime N, Umemura Y, Matsushima A, Fushimi K. Temporal trends of medical cost and cost-effectiveness in sepsis patients: a Japanese nationwide medical claims database. Journal of intensive care 2022; 10: 33.

Saito D, Imaeda T, Oshima T, Karasawa S, Nakada TA. Sheath introducer accidentally placed in the artificial graft while introducing extracorporeal membrane oxygenation. Acute medicine & surgery 2022; 9: e761.

Wada T, Yamakawa K, Kabata D, Abe T, Ogura H, Shiraishi A, Saitoh D, Hifumi T, Kushimoto S, Fijishima S, Mayumi T, Hifumi T, Shiino Y, Nakada TA, Tarui T, Otomo T, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Masumo T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Hujimi S, Gando S. Age-related differences in the survival benefit of the administration of antithrombin, recombinant human thrombomodulin, or their combination in sepsis. Scientific reports 2022; 12: 9304.

Jonckheer J, Hoorn AV, Oshima T, Waele ED. Bioenergetic balance of continuous venovenous hemofiltration, a retrospective analysis. Nutrients 2022; 14: 2112.

Yamasoba D, Kimura I, Nasser H, Morioka Y, Nao N, Ito J, Uriu K, Tsuda M, Zahradnik J, Shirakawa K, Suzuki R, Kishimoto M, Kosugi Y, Kobiyama K, Hara T, Toyoda M, Tanaka YL, Butlertanaka EP, Shimizu R, Ito H, Wang L, Oda Y, Orba Y, Sasaki M, Nagata K, Yoshimatsu K, Asakura H, Nagashima M, Sadamasu K, Yoshimura K, Kuramochi J, Seki M, Fujiki R, Kaneda A, Shimada T, Nakada TA. Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike. Cell 2022; 185: 2103-2115.

Hayashi Y, Hashida T, Yazaki M, Uchida T, Watanabe E. Posterior reversible encephalopathy syndrome (PRES) of the isolated brainstem. Clinical case reports 2022; 10: e05712.

Matsumura Y, Shiraishi A, Kushimoto S. Minimising the biases in the observational study of resuscitative endovascular balloon occlusion of the aorta: a research protocol for a prospective study analysed with propensity score matching with time-varying covariates. BMJ open 2022; 12: e053743.

Watanabe E, Akamatsu T, Ohmori M, Kato M, Takeuchi N, Ishiwada N, Nishimura R, Hishiki H, Fujimura L, Ito C, Hatano M. Recombinant thrombomodulin attenuates hyper-inflammation and glycocalyx damage in a murine model of Streptococcus pneumoniae-induced sepsis. Cytokine 2022; 149: 155723.

Watanabe E, Takasu O, Teratake Y, Sakamoto T, Ikeda T, Kotani J, Kitamura N, Ohmori M, Teratani A, Honda G, Hatano M, Mayer B, Schneider EM, Oda S. A thrombomodulin promoter gene polymorphism, rs2239562, influences both susceptibility to and outcome of sepsis. Frontiers in medicine 2022; 8: 762198.

Yamazaki S, Watanabe K, Okuda Y, Urushihara M, Koshikawa H, Chiba H, Yahaba M, Taniguchi T, Nakada TA, Nakajima H, Ishii I, Igari H. Adverse effect investigation using application software after vaccination against SARS-CoV-2 for healthcare workers. Journal of infection and chemotherapy 2022; 28: 791-796.

Umemura Y, Abe T, Ogura H, Fujishima S, Kushimoto S, Shiraishi A, Saitoh D, Mayumi T, Otomo Y, Hifumi T, Hasegawa A, Takuma K, Yamakawa K, Shiino Y, Nakada TA, Tarui T, Okamoto K, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Tsuruta R, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Gando S. Hour-1 bundle adherence was associated with reduction of in-hospital mortality among patients with sepsis in Japan. PloS one 2022; 17: e0263936.

Niibe Y, Suzuki T, Yamazaki T, Uchida M, Suzuki T, Takahashi N, Hattori N, Nakada TA, Ishii I. Identification of factors affecting meropenem pharmacokinetics in critically ill patients: Impact of inflammation on clearance. Journal of infection and chemotherapy 2022; 28: 532-538.

Nakamura K, Hatakeyama J, Liu K, Kanda N, Yamakawa K, Nishida T, Ohshimo S, Inoue S, Hashimoto S, Maruyama S, Kawakami D, Ogata Y, Hayakawa K, Shimizu H, Oshima T, Fuchigami T, Nishida O. Relationship between nutrition therapy in the acute phase and outcomes of ventilated patients with COVID-19 infection: a multicenter prospective observational study. The American journal of clinical nutrition 2022; 115: 1115-1122.

2021

Wada T, Shiraishi A, Gando S, Yamakawa K, Fujishima S, Saitoh D, Kushimoto S, Ogura H, Abe T, Mayumi T, Sasaki J, Kotani J, Takeyama N, Tsuruta R, Takuma K, Shiraishi S, Shiino Y, Nakada TA, Okamoto K, Sakamoto Y, Hagiwara A, Fujimi S, Umemura Y, Otomo Y. Pathophysiology of coagulopathy induced by traumatic brain injury is identical to that of disseminated intravascular coagulation with hyperfibrinolysis. Frontiers in medicine 2021; 8: 767637.

Nakayama N, Uemura H, Uchida Y, Imai Y, Tomiya T, Terai S, Yoshiji H, Genda T, Ido A, Inoue K, Kato N, sakaida U, Shimizu M, Takikawa Y, Abe M, Abe R, Chayama K, Hasegawa K, Inui A, Kasahara M, Ohira K, Tanaka A, Takikawa H, Mochida S. Nationwide survey for patients with acute-on-chronic liver failure occurring between 2017 and 2019 and diagnosed according to proposed Japanese criteria. Journal of gastroenterology 2021; 56: 1092-1106.

Ishikawa S, Teshima Y, Otsubo H, Shimazui T, Nakada TA, Matsuda K, Sasaki J, Nabeta M, Moriguchi T, Shibusawa T, Mayumi T, Oda S. Risk prediction of biomarkers for early multiple organ dysfunction in critically ill patients. BMC emergency medicine 2021; 21: 132.

Uriu K, Kimura I, Shirakawa K, Takaori-Kondo A, Nakada TA, Nakagawa S, Sato K, Genotype to Phenotype (G2P-Japan) Consortium. Neutralization of the SARS-CoV-2 Mu variant by convalescent and vaccine serum. The New England journal of medicine 2021; 385: 2397-2399.

Tanaka K, Nakada TA, Takahashi N, Dozono T, Yoshimura Y, Yokota H, Horikoshi T, Nakaguchi T, Shinozaki K. Superiority of supervised machine learning on reading chest X-rays in intensive care units. Frontiers in medicine 2021; 8: 676277.

Ono R, Kajiyama T, Hattori N, Kobayashi Y. Sore hand syndrome. The American journal of medicine 2021; 134: e433-e434.

Hayashi Y, Shimada T, Hattori N, Shimazui T, Yoshida Y, Miura RE, Yamao Y, Abe R, Kobayashi E, Iwadate Y, Nakada TA. A prehospital diagnostic algorithm for strokes using machine learning: a prospective observational study. Scientific reports 2021; 11: 20519.

Nakashima I, Horibe M, Sanui M, Sasaki M, Sawano H, Goto T, Ikeura T, Takeda T, Oda T, Yasuda H, Ogura Y, Miyazaki D, Kitamura K, Chiba N, Ozaki T, Yamashita T, Koinuma T, Oshima T, Yamamoto T, Hirota M, Moriya T, Shirai K, Izai J, Takeda K, Sekino M, Iwasaki E, Kanai T, Mayumi T. Impact of Enteral Nutrition within 24 hours versus between 24 and 48 hours in patients with severe acute pancreatitis: a multicenter retrospective study. Pancreas 2021; 50: 371-377.

Shimazui T, Nakada TA, Yazaki M, Mayumi T, Takasu O, Matsuda K, Sasaki J, Otsubo H, Teshima Y, Nabeta M, Moriguchi T, Shibusawa T, Oda S. Blood interleukin-6 levels predict multiple organ dysfunction in critically ill patients. Shock 2021; 55: 790-795.

Imaeda T, Nakada TA, Takahashi N, Yamao Y, Nakagawa S, Ogura H, Shime N, Umemura Y, Matsushima A, Fushimi K. Trends in the incidence and outcome of sepsis using data from a Japanese nationwide medical claims database-the Japan Sepsis Alliance (JaSA) study group. Critical care 2021; 25: 338.

Egi M, Ogura H, Yatabe Y, Atagi K, Inoue S, Iba T, Kakihana Y, Kawasaki T, Kushimoto S, Kuroda Y, Kotani J, Shime N, Taniguchi T, Tsuruta R, Doi K, Doi M, Nakada TA, Nakane M, Fujishima S, Hosokawa N, Masuda Y, Matsushima A, Matsuda N, Yamakawa K, Hara Y, Sakuraya M, Ohshimo S, Aoki Y, Inada M, Umemura Y, et al. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020). Acute medicine & surgery 2021; 8: e659.

Karasawa S, Nakada TA, Sato M, Miyasho T, Shimada T, Oshima T, Suda K, Shinozaki K, Oda S. Early elevation of cell-free DNA after acute mesenteric ischemia in rats. The Journal of surgical research 2021; 269: 28-35.

Shionoya Y, Taniguchi T, Kasai H, Sakuma N, Imai S, Shikano K, Takayanagi S, Yahaba M, Nakada TA, Igari H, Sakao S, Suzuki T. Possibility of deterioration of respiratory status when steroids precede antiviral drugs in patients with COVID-19 pneumonia: A retrospective study. PloS one 2021; 16: e0256977.

Hongo T, Naito H, Fujiwara T, Naito T, Homma Y, Fujimoto Y, Takaya M, Yamamori Y, Nakada TA, Nojima T, Nakao A, Fujitani S, In‐Hospital Emergency Study Group . Prevalence and predictors of direct discharge home following hospitalization of patients with serious adverse events managed by the rapid response system in Japan: a multicenter, retrospective, observational study. Acute medicine & surgery 2021; 8: e690.

Egi M, Ogura H, Yatabe T, Atagi K, Inoue S, Iba T, Kakihana Y, Kawasaki T, Kushimoto S, Kuroda Y, Kotani J, Shime N, Taniguchi T, Tsuruta R, Doi K, Nakada TA, Nakane M, Fujishima S, Hosokawa N, Masuda Y, Matsushima A, Matsuda N, Yamakawa K, Hara Y, Sakuraya M, Ohshimo S, Aoki Y, Inaba M, Umemura Y, Kawai Y, et al. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020). Journal of intensive care 2021; 9: 53.

Takahashi Y, Gu Y, Nakada TA, Abe R, Nakaguchi T. Estimation of respiratory rate from thermography using respiratory likelihood index. Sensors 2021; 21: 4406.

Chen CW, Bennion KB, Swift DA, Morrow KN, Zhang W, Oami T, Coopersmith CM, Ford ML. Tumor-Specific T Cells Exacerbate Mortality and Immune Dysregulation during Sepsis. Journal of immunology 2021; 206: 2412-2419.

Kageyama T, Ikeda K, Tanaka S, Taniguchi T, Igari H, Onouchi Y, Kaneda A, Matsushita K, Hanaoka H, Nakada TA, Ohtori S, Yoshino I, Matsubara H, Nakayama T, Yokote K, Nakajima H. Antibody responses to BNT162b2 mRNA COVID-19 vaccine and their predictors among healthcare workers in a tertiary referral hospital in Japan. Clinical microbiology and infection. 2021. [Online ahead of print.]

Shibahashi K, Sugiyama K, Kuwahara Y, Ishida T, Sakurai A, Kitamura N, Tagami T, Nakada TA, Takeda M, Hamabe Y; SOS-KANTO 2012 Study Group. External validation of simplified out-of-hospital cardiac arrest and cardiac arrest hospital prognosis scores in a Japanese population: a multicentre retrospective cohort study. The American journal of emergency medicine. 2021. [Online ahead of print.]

Wada T, Shiraishi A, Gando S, Yamakawa K, Fujishima S, Saitoh D, Kushimoto S, Ogura H, Abe T, Mayumi T, Sasaki J, Kotani J, Takeyama N, Tsuruta R, Takuma K, Yamashita N, Shiraishi SI, Ikeda H, Shiino Y, Tarui T, Nakada TA, Hifumi T, Okamoto K, Sakamoto Y, Hagiwara A, Masuno T, Ueyama M, Fujimi S, Umemura Y, Otomo Y. Disseminated intravascular coagulation immediately after trauma predicts a poor prognosis in severely injured patients.Scientific reports. 2021; 11: 11031.

Naito T, Hayashi K, Hsu HC, Aoki K, Nagata K, Arai M, Nakada TA, Suzaki S, Hayashi Y, Fujitani S; In‐Hospital Emergency Study Group.Validation of National Early Warning Score for predicting 30-day mortality after rapid response system activation in Japan. Acute Med Surg. 2021; 8: e666.

Fujishima S, Gando S, Saitoh D, Kushimoto S, Ogura H, Abe T, Shiraishi A, Mayumi T, Sasaki J, Kotani J, Takeyama N, Tsuruta R, Takuma K, Yamashita N, Shiraishi SI, Ikeda H, Shiino Y, Tarui T, Nakada TA, Hifumi T, Otomo Y, Okamoto K, Sakamoto Y, Hagiwara A, Masuno T, Ueyama M, Fujimi S, Yamakawa K, Umemura Y. JAAM Focused Outcomes Research on Emergency Care for Acute respiratory distress syndrome, Sepsis and Trauma (FORECAST) Group. Incidence and Impact of Dysglycemia in Patients with Sepsis Under Moderate Glycemic Control. Shock. 2021. [Online ahead of print.]

Yamamoto R, Sasaki J, Shibusawa T, Nakada TA, Mayumi T, Takasu O, Matsuda K, Shimazui T, Otsubo H, Teshima Y, Nabeta M, Moriguchi T, Oda S. Accuracy for Mortality Prediction With Additive Biomarkers Including Interleukin-6 in Critically Ill Patients: A Multicenter Prospective Observational Study. Critical care explorations. 2021; 3: e0387.

Yamamoto R, Fujishima S, Sasaki J, Gando S, Saitoh D, Shiraishi A, Kushimoto S, Ogura H, Abe T, Mayumi T, Kotani J, Nakada TA, Shiino Y, Tarui T, Okamoto K, Sakamoto Y, Shiraishi SI, Takuma K, Tsuruta R, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Hifumi T, Yamakawa K, Hagiwara A, Otomo Y; Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis and Trauma (FORECAST) Study Group. Hyperoxemia during resuscitation of trauma patients and increased intensive care unit length of stay: inverse probability of treatment weighting analysis. World journal of emergency surgery. 2021; 16: 19.

Takahashi N, Nakada TA, Walley KR, Russell JA. Significance of lactate clearance in septic shock patients with high bilirubin levels. Scientific reports 2021; 11: 6313.

Oami T, Karasawa S, Shimada T, Nakada TA, Abe T, Ogura H, Shiraishi A, Kushimoto S, Saitoh D, Fujishima S, Mayumi T, Shiino Y, Tarui  T, Hifumi T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, et al. Association between low body mass index and increased 28-day mortality of severe sepsis in Japanese cohorts. Scientific reports 2021; 11: e1615.

Kuroiwa R, Tateishi Y, Oshima T, Inagaki T, Furukawa S, Takemura R, Kawasaki Y, Murata A. Mechanical Insufflation-exsufflation for the Prevention of Ventilator-associated Pneumonia in Intensive Care Units: A Retrospective Cohort Study. Indian journal of critical care medicine 2021; 25: 62-66.

Hagiwara A, Tanaka N, Inaba Y, Gando S, Shiraishi A, Saitoh D, Otomo Y, Ikeda H, Ogura H, Kushimoto S, Kotani J, Sakamoto Y, Shiino Y, Shiraishi S, Takuma K, Tarui T, Tsuruta R, Nakada TA, Hifumi T, Yamakawa K, Takeyama N, Yamashita N, Abe T, Ueyama M, Okamoto K, Sasaki J, Masuno T, Mayumi T, Fujishima S, Umemura Y, Fujimi S. Predictors of severe sepsis-related in-hospital mortality based on a multicenter cohort study: The Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis, and Trauma study. Medicine 2021; 100: e24844.

Hirasawa Y, Nakada TA, Shimazui T, Abe M, Isaka Y, Sakayori M, Suzuki K, Yoshioka K, Kawasaki T, Terada J, Tsushima K, Tatsumi K. Prognostic value of lymphocyte counts inbronchoalveolar lavage fluid in patientswith acute respiratory failure: a retrospective cohort study. Journal of Intensive Care 2021; 9: 21.

Shimazui T, Nakada TA, Kuroiwa S, Toyama Y, Oda S. Speech recognition shortens the recording time of prehospital medical documentation. American Journal of Emergency Medicine 2021. [Online ahead of print]

Takikawa Y, Kakisaka K, Suzuki Y, Ido A, Shimamura T, Nishida O, Oda S, Shimosegawa T. Multicenter study on the consciousness-regaining effect of a newly developed artificial liver support system in acute liver failure: An on-line continuous hemodiafiltration system. Hepatology research 2021; 51: 216-226.

Yamazaki S, Suzuki T, Sayama M, Nakada TA, Igari H, Ishi I. Suspected cholestatic liver injury induced by favipiravir in a patient with COVID-19. Journal of infection and chemotherapy 2021; 27: 390-392.

2020

Umemura Y, Ogura H, Takuma K, Fijishima S, Abe T, Kushimoto S, Hifumi T, Hagiwara a, Shiraishi A, Otomo Y, Saitoh D, Mayumi T, Yamakawa K, Shiino Y, Nakada TA, Tarui T, Okamoto k, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Tsuruta R, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Gando S, et al. Current spectrum of causative pathogens in sepsis: a prospective nationwide cohort study in Japan. International journal of infectious diseases 2021; 103: 343-351.

Hayakawa M, Tagami T, Iijima H, Kudo D, Sekine K, Ogura T, Yumoto T, Kondo Y, Endo A, Ito K, Matsumura Y, Kushimoto S. Restrictive transfusion strategy for critically injured patients (RESTRIC) trial: a study protocol for a cluster-randomised, crossover non-inferiority trial. BMJ Open 2020; 10: e037238.

Takikawa Y, Kakisaka K, Suzuki Y, Ido A, Shimamura T, Nishida O, Oda S, Shimisegwa T. Multicenter study on the consciousness-regaining effect of a newly developed artificial liver support system in acute liver failure: An on-line continuous hemodiafiltration system. Hepatology research 2020. [Online ahead of print]

McGreevy DT, Abu-Zidan FM, Sadeghi M, Pirouzram A, Toivola A, Skoog P, Idoguchi K, Kon Y, Ishida T, Matsumura Y, Matsumoto J, Reva V, Maszkowski M, Bersztel A, Caragounis EC, Falkenberg M, Handolin L, Oosthuizen G, Szarka E, Manchev V, Wannatoop T, Chang SW, Kessel B, Hobron D, Shaked G, Bala M, Coccolini F, Ansaloni L, Ordonez CA, Dofan EM, et al. Feasibility and clinical outcome of REBOA in patients with impending traumatic cardiac arrest. SHOCK 2020; 54: 218-223.

Otani S, Oami T, Yoseph BP, Klimgensmith NJ, Chen CW, Liang Z, Coopersmith CM. Overexpression of Bcl-2 in the intestinal epithelium prevents sepsis-induced gut barrier function via altering tight junction protein expression. Shock 2020; 54: 330-336.

Imaeda T, Hattori N, Abe R, Iwase S, Saito D, Koizumi K, Chaisirin W, Taniguchi T, Nakada TA. Interhospital transportation of a COVID-19 patient undergoing veno-venous extracorporeal membrane oxygenation by helicopter. The American journal of emergency medicine 2020. [Online ahead of print]

Komori A, Abe T, Yamakawa K, Ogura H, Kushimoto S, Saitoh D, Fujishima S, Otomo Y, Kotani J, Sakamoto Y, Sasaki J, Shiino Y, Takeyama N, Tarui T, Tsuruta R, Nakada TA, Hifumi T, Iriyama H, Naito T, Gando S, JAAM SPICE Study Group. Characteristics and outcomes of frail patients with suspected infection in intensive care units: a descriptive analysis from a multicenter cohort study. BMC geriatrics 2020; 20: 485.

Aoki M, Abe T, Matsumura Y, Hagiwara Y, Saitoh D, Oshima K. The off-hour effect among severe trauma patients: a nationwide cohort study in Japan. Surgery today 2020; 50: 1480-1485.

Hifumi T, Fujishima S, Ubukata K, Hagiwara A, Abe T, Ogura H, Shraishi A, Kushimoto S, Saitoh D, Mayumi T, Ikeda H, Ueyama M, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiino J, Shiraishi S, Takuma K, Tarui T, Tsuruta R, Nakada TA, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Fujimi S, Gando S, JAAM FORECAST group. Clinical characteristics of patients with severe sepsis and septic shock in relation to bacterial virulence of beta-hemolytic Streptococcus and Streptococcus pneumoniae. Acute medicine & surgery 2020; 7: e513.

Matsumura Y, Higashi A, Izawa Y, Hishikawa S, Kondo H, Reva V, Matsumoto J. Organ ischemia during partial resuscitative endovascular balloon occlusion of the aorta: Dynamic 4D Computed tomography in swine. Scientific reports 2020; 10: 5680.

Shimazui T, Nakada TA, Walley KR, Oshima T, Abe T, Ogura H, Shiraishi A, Kushimoto S, Saitoh D, Fujishima S, Mayumi T, Shiino Y, Tarui T, Hifumi T, Otomo Y, Okamoto K, Umeyama Y, kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Yakuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, et al. Significance of body temperature in elderly patients with sepsis. Critical care 2020; 24: 387.

Abe T, Yamakawa K, Ogura H, Kushimoto S, Saitoh D, Fujishima S, Otomo Y, Kotani J, Umemura Y, Sakamoto Y, Sasaki J, Shiino Y, Takeyama N, Tarui T, Shiraishi S, Tsuruta R, Nakada TA, Hifumi T, Hagiwara A, Ueyama M, Yamashita N, Masuno T, Ikeda H, Komori A, Iriyama H, Gando S, JAAM SPICE Study Group . Epidemiology of sepsis and septic shock in intensive care units between sepsis-2 and sepsis-3 populations: sepsis prognostication in intensive care unit and emergency room（SPICE-ICU）. Journal of intensive care 2020; 8: 44.

Takahashi N, Abe R, Hattori N, Matsumura Y, Oshima T, Taniguchi T, Igari H, Nakada TA. Clinical course of a critically ill patient with severe acute respiratory syndrome coronavirus 2（SARS-CoV-2）. Journal of artificial organs 2020; 23: 397-400.

Higashi A, Nakada TA, Imaeda T, Abe R, Shinozaki K, Oda S. Shortening of low-flow duration over time was associated with improved outcomes of extracorporeal cardiopulmonary resuscitation in in-hospital cardiac arrest. Journal of intensive care 2020; 8: 39.

Watanabe E, Nishida O, Kakihana Y, Odani M, Okamura T, Harada T, Oda S. Pharmacokinetics, pharmacodynamics, and safety of nivolumab in patients with sepsis-induced immunosuppression: A multicenter, open-label phase 1/2 study. Shock 2020; 53: 686-694.

Delsoglio M, Dupertuis YM, Oshima T, van der Plas M, Pichard C. Evaluation of the accuracy and precision of a new generation indirect calorimeter in canopy dilution mode. Clinical nutrition 2020; 39: 1927-1934.

Suzuki Shuji, Kondo H, Furukawa A, Kawai K, Yukaya T, Shimazui T, Tani M, Yamamoto M. Prognostic Factors of Preoperative Examinations for Non-occlusive Mesenteric Ischemia: A Multicenter Retrospective Project Study Conducted by the Japanese Society for Abdominal Emergency Medicine. World Journal of Surgery 2020; 44: 3687-3694.

Kawasaki M, Nakano K, Ohnishi T, Sekine M, Watanabe E, Oda S, Nakada TA, Haneishi H. Investigation into effect of thrombomodulin alfa for septic model rats based on microcirculation image analysis. Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2020; 2020: 1844-1847.

Oshima T, Delsoglio M, Dupertuis YM, Singer P, De Waele E, VeraarDe Waele C, Heidegger CP, Wernermann J, Wischmeyer PE, Berger MM, Pichard C. The clinical evaluation of the new indirect calorimeter developed by the ICALIC project. Clinical nutrition 2020. [Epub ahead of print]

Jonckheer J, Spapen H, Malbrain MLNG, Oshima T, De Waele E. Energy expenditure and caloric targets during continuous renalreplacement therapy under regional citrate anticoagulation. A viewpoint. Clinical nutrition 2020; 39: 353-357.

Niibe Y, Suzuki T, Yamazaki S, Suzuki T, Takahashi N, Hattori N, Nakada TA, Oda S, Ishii I. Population pharmacokinetic analysis of meropenem in critically ill patients with acute kidney injury treated with continuous hemodiafiltration. Therapeutic drug monitoring 2020; 42: 588-594.

Yasuda H, Horibe M, Sanui M, Sasaki M, Suzuki N, Sawano H, Goto T, Ikeura T, Takeda T, Oda T, Ogura Y, Miyazaki D, Kitamura K, Chiba N, Ozaki T, Yamashita T, Koinuma T, Oshima T, Yamamoto T, Hirota M, Sato M, Miyamoto K, Mine T, Misumi T, Takeda Y, Iwasaki E, Kanai T, Mayumi T. Etiology and mortality in severe acute pancreatitis: A multicenter study in Japan. Pancreatology 2020; 20: 307-317.

Minami K, Horibe M, Sanui M, Sasaki M, Sasaki M, Iwasaki E, Sawano H, Goto T, Ikeura T, Takeda T, Oda T, Yasuda H, Ogura Y, Miyazaki D, Kitamura K, Chiba N, Ozaki T, Yamashita T, Koinuma T, Oshima T, Yamamoto T, Hirota M, Tokuhira N, Azumi Y, Nagata K, Takeda K, Furuya T, Lefor AK, Mayumi T, Kanai T. The effect of an invasive strategy for treating pancreatic necrosis on mortality: a retrospective multicenter cohort study. Journal of gastrointestinal surgery 2020; 9: 2037-2045.

Izawa Y, Hishikawa S, Matsumura Y, Nakamura H, Sugimoto H, Mato T. Blood flow of venous system during resuscitative endovascular balloon occlusion of the aorta: Non-invasive evaluation using a phase contrast MRI. The journal of trauma and acute care surgery 2019; 87: 1156-1163.

Takahashi N, Nakada TA, Sakai T, Kato Y, Moriyama K, Nishida O, Oda S. A CO2 removal system using extracorporeal lung and renal assist device with an acid and alkaline infusion. J Artif Organs. 2020; 23: 54-61.

Kushimoto S, Abe T, Ogura H, Shiraishi A, Saitoh D, Fujishima S, Mayumi T, Hifumi T, Shiino Y, Nakada TA, Tarui T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Fujimi S, Gando S, JAAM FORECAST group. Impact of blood glucose abnormalities on outcomes and disease severity in patients with severe sepsis: An analysis from a multicenter, prospective survey of severe sepsis. PloS one. 2020; 15: e0229919. 

Abe T, Suzuki T, Kushimoto S, Fijishima S, Sugiyama T, Iwagami M, Ogura H, Shiraishi A, Saitoh D, Mayumi T, Iriyama H, Komori A, Nakada TA, Shiino Y, Tarui T, Hifumi T, Otomo Y, Okamoto K, Uemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Tsuruta R, Hagiwara A, Yamakawa K, Takuma K, Masuno T, Takeyama N, Yamashita N, et al. History of diabetes may delay antibiotic administration in patients with severe sepsis presenting to emergency departments. Medicine 2020; 99: e19446.

Nakata H, Yamakawa K, Kabata D, Umemura Y, Ogura H, Gando S, Shintani A, Shiraishi A, Saitoh D, Fujishima S, Mayumi T, Kushimoto S, Abe T, Shiino Y, Nakada TA, Tarui T, Hifumi T, Otomo Y, Okamoto K, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Masuno T, Takeyama N, Yamashita N, Ikeda H, et al. Identifying septic shock populations benefitting from polymyxin B hemoperfusion: A prospective cohort study incorporating a restricted cubic spline regression model. Shock. 2020; doi: 10.1097/SHK.0000000000001533.

Shibahashi K, Sugiyama K, Kuwahara Y, Ishida T, Sakurai A, Kitamura N, Tagami T, Nakada TA, Takeda M, Hamabe Y. Private residence as a location of cardiac arrest may have a deleterious effect on the outcomes of out-of-hospital cardiac arrest in patients with an initial non-shockable cardiac rhythm: A multicentre retrospective cohort study. Resuscitation. 2020; 150: 80-89.

Nakada TA, Oda S, Abe R, Hattori N. Changes in acute blood purification therapy in critical care: republication of the article published in the Japanese Journal of Artificial Organs. J Artif Organs. 2020; 23: 14-18.

Iriyama H, Abe T, Kushimoto S, Fujishima S, Ogura H, Shiraishi A, Saitoh D, Mayumi T, Naito T, Komori A, Hifumi T, Shiino Y, Nakada TA, Tarui T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, et al. Risk modifiers of acute respiratory distress syndrome in patients with non-pulmonary sepsis: a retrospective analysis of the FORECAST study. J Intensive Care. 2020; 8: e7.

Nishiyama A, Kawata N, Yokota H, Sugiura T, Matsumura Y, Higashide T, Horikoshi T, Oda S, Tatsumi K, Uno T. A predictive factor for patients with acute respiratory distress syndrome: CT lung volumetry of the well-aerated region as an automated method. Eur J Radiol. 2020; 122: 108748.

Komori A, Abe T, Kushimoto S, Ogura H, Shiraishi A, Saitoh D, Fujishima S, Mayumi T, Naito T, Hifumi T, Shiino Y, Nakada TA, Tarui T, Otomo Y, Okamoto K, Uemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Fujimi S, et al. Characteristics and outcomes of bacteremia among ICU-admitted patients with severe sepsis. Sci Rep. 2020; 10: 2983.

Gando S, Fujishima S, Sarto D, Shiraishi A, Yamakawa K, Kushimoto S, Ogura H, Abe T, Mayumi T, Sasaki J, Kotani J, Takeyama N, Tsuruta R, Takuma R, Yamashita N, Shiraishi S, Ikeda H, Shiino Y, Tarui T, Nakada TA, Hifumi T, Otomo Y, Okamoto K, Sakamoto Y, Hagiwara A, Masuno T, Ueyama M, Fujimi S, Umemura Y, on behalf of the Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis and Trauma (FORECAST) Study Group. The significance of disseminated intravascular coagulation on multiple organ dysfunction during the early stage of acute respiratory distress syndrome. Thromb Res. 2020; 191: 15-21.

2019

Yamakawa Y, Gando S, Ogura H, Umemura Y, Kabata D, Shintani A, Saitoh D, Fujishima S, Mayumi T, Kushimoto S, Abe T, Shiino Y, Nakada TA, Hifumi T, Otomo Y, Okamoto K, Kotani J, Sakamoto Y, Sasaki J, Shiraishi SI, Takuma K, Tsuruta R, Hagiwara A, Masuno T, Takeyama N, Yamashita N, Ikeda H, Fujimi M, Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis Trauma (FORECAST) Study Group . Identifying Sepsis Populations Benefitting from Anticoagulant Therapy: A Prospective Cohort Study Incorporating a Restricted Cubic Spline Regression Model. Thrombosis and haemostasis 2019; 119: 1740-1751.

Abe T, Ogura H, Kushimoto S, Shiraishi A, Sugiyama T, Deshpande GA, Uchida M, Nagata I, saitoh D, Fujishima S, Mayumi T, Hifimi T, Shiino Y, Nakada TA, Tarui T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, et al. Variations in infection sites and mortality rates among patients in intensive care units with severe sepsis and septic shock in Japan. Journal of intensive care 2019; 7: e28.

Kushimoto S, Abe T, Ogura H, Shiraishi A, Saitoh D, Fujishima S, Mayumi T, Hifumi T, Shiino Y, Nakada TA, Tarui T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama N, Fujimi S, Gando S, et al, JAAM Focused Outcome Research on Emergency Care for Acute respiratory distress syndrome, Sepsis and Trauma (FORECAST) Group . Impact of body temperature abnormalities on the implementation of sepsis bundles and outcomes in patients with severe sepsis: A retrospective sub-analysis of the focused outcome research on emergency care for acute respiratory distress syndrome, sepsis and. Critical care medicine 2019; 47: 691-699.

Otani S, Coopersmith CM. Gut integrity in critical illness. Journal of intensive care 2019; 20: 17.

Otani S, Chihade DB, Coopersmith CM. Critical illness and the role of the microbiome . Acute medicine & surgery 2019; 6: 91-94.

Coccolini F, Moore EE, Kluger Y, Biffl W, Leppaniemi A, Matsumura Y, kim F, Peitzman AB, Fraga GP, Sartelli M, Ansaloni L, Augustin G, Kirkpatrick A, Abu-Zidan F, Wani I, Weber D, Pikoulis E, Larrea M, Arvieux C, Manchev V, Reva V, Coimbra R, Khokha V, Mefire AC, Ordonez C, Chiarugi M, Machado F, Sakakushev B, Matsumoto J, Majer R, et al. Kidney and uro-trauma: WSES-AAST guidelines. World journal of emergency surgery 2019; 14: 54.

Coccolini F, Kobayashi L, Kluger Y, Moore EE, Ansaloni L, Biff W, Leppaniemi A, Augustin G, Reva V, Wani I, Kirkpatrick A, Abu-Zidan F, Cicuttin E, Fraga GP, Ordonez C, Pikoulis E, Sibilla MG, Majer R, Matsumura Y, Masiakos PT, Khokha V, Mefire AC, Ivatury R, Favi F, Manchev V, Sartelli M, Machado F, Matsumoto J, Chiarugi M, Arvieux C, et al. Duodeno-pancreatic and extrahepatic biliary tree trauma: WSES-AAST guidelines. World journal of emergency surgery 2019; 14: 56.

Matsumura Y, Shiraishi A. Addressing Limitations in Case-Control Study of Patients Undergoing Resuscitative Endovascular Balloon Occlusion of the Aorta. JAMA surgery 2019; 154: 1165.

Umeyama Y, Ogura H, Gando S, Shiraishi A, Saitoh D, Fujishima S, Mayumi T, Kushimoto S, Abe T, Shiino Y, Nakada TA, Tarui T, Hifumi T, Otomo Y, Okamoto K, Kotani j, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Yamakawa K, Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis and Trauma (FORECAST) Study Group . Prognostic Accuracy of Quick SOFA is different according to the severity of illness in infectious patients. Journal of infection and chemotherapy 2019; 25: 943-949.

Horibe M, Sanui M, Sasaki M, Honda H, Ogura Y, Namiki S, Sawano H, Goto T, Ikeura T, Takeda T, Oda T, Yasuda H, Miyazaki D, Hirose K, Kitamura K, Chiba N, Ozaki T, Yamashita T, Koinuma T, Oshima T, Yamamoto T, Hirota M, Yamamoto S, Oe K, Ito T, Masuda Y, Saito N, Iwasaki E, Kanai T, Mayumi T. Impact of antimicrobial prophylaxis for severe acute pancreatitis on the development of invasive candidiasis: a large retrospective multicenter cohort study. Pancreas 2019; 48: 537-543.

Klingensmith NJ, Fay KT, Lyons JD, Chen CW, Otani S, Liang Z, Chihade DB, Burd EM, Ford ML, Coopersmith CM. Chronic alcohol ingestion worsens survival and alters gut epithelial apoptosis and CD8+ T Cell function after pseudomonas aeruginosa pneumonia-induced epsis. Shock 2019; 51: 453-463.

Oami T, Chihade DB, Coopersmith CM. The microbiome and nutrition in critical illness. Current opinion in critical care 2019; 25: 145-149.

Naito T, Fujiwara S, Kawasaki T, Sento Y, Nakada TA, Arai M, Atagi K, Fujitani S, In‐Hospital Emergency Study Group. First report based on the online registry of a Japanese multicenter rapid response system: a descriptive study of 35 institutions in Japan. Adute Med Surg. 2019; 7: e454.

Shinozaki M, Nakada TA, Kawaguchi R, Yoshimura Y, Nakaguchi T, Haneishi H, Oda S. Feedback function for capillary refilling time measurement device. Crit Care 2019; 23: 295.

Fukuma H, Nakada TA, Shimada T, Shimazui T, Aizimu T, Nakao S, Watanabe H, Mizushima Y, Matsuoka T. Prehospital lactate improves prediction of the need for immediate interventions for hemorrhage after trauma. Sci Rep. 2019; 9: 13755.

Shimada T, Topchiy E, Leung AKK, Kong HJ, Genga KR, Boyd JH, Russell JA, Oda S, Nakada TA, Hirasawa H, Walley KR. Very Low Density Lipoprotein Receptor Sequesters Lipopolysaccharide into Adipose Tissue During Sepsis. Crit Care Med. 2019; 48: 41-48.

Matsumura Y, Higashi A, Izawa Y, Hishikawa S, Kondo H, Reva V, Oda S, Matsumoto J. Distal pressure monitoring and titration with percent balloon volume: feasible management of partial resuscitative endovascular balloon occlusion of the aorta（P-REBOA）. Eur J Trauma Emerg Surg. 2019; doi: 10.1007/s00068-019-01257-4.

Abe T, Kushimoto S, Tokuda Y, Phillips GS, Rhodes A, Sugiyama T, Komori A, Iriyama H, Ogura H, Fujishima S, Shiraishi A, Saitoh D, Mayumi T, Naito T, Takuma K, Nakada TA, Shiino Y, Tarui T, Hifumi T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, et al. Implementation of earlier antibiotic administration in patients with severe sepsis and septic shock in Japan: a descriptive analysis of a prospective observational study. Crit Care. 2019; 23: e360.

Kurita T, Nakada TA, Kawaguchi R, Fujitani S, Atagi K, Naito T, Arai M, Arimoto H, Masuyama T, Oda S, IHER-J collaborators. Impact of increased calls to rapid response systems on unplanned ICU admissions: Japanese database study. Am J Emerg Med. 2019; doi: 10.1016/j.ajem.2019.10.028.

Komori A, Abe T, Kushimoto S, Ogura H, Shiraishi A, Deshpande GA, Saitoh D, Fujishima S, Mayumi T, Gando S, JAAM FORECAST group. Clinical features of patients with candidemia in sepsis. J Gen Fam Med. 2019; 20: 161-163.

Yamashita T, Horibe M, Sanui M, Sasaki M, Sawano H, Goto T, Ikeura T, Hamada T, Oda T, Yasuda H, Ogura Y, Miyazaki D, Hirose K, Kitamura K, Chiba N, Ozaki T, Koinuma T, Oshima T, Yamamoto T, Hirota M, Masuda Y, Tokuhira N, Kobayashi M, Saito S, Izai J, Lefor AK, Iwasaki E, Kanai T, Mayumi T. Large volume fluid resuscitation for severe acute pancreatitis is associated with reduced mortality: A multicenter retrospective study. J Clin Gastroenterol. 2019; 53: 385-391.

Tomita K, Nakada TA, Oshima T, Motoshima T, Kawaguchi R, Oda S. Tau protein as a diagnostic marker for diffuse axonal injury. PloS One. 2019; 14: e0214381.

Shimazui T, Nakada TA, Tateishi Y, Aizimu T, Oda S. Association between serum levels of interleukin-6 on ICU admission and subsequent outcomes in critically ill patients with acute kidney injury. BMC Nephrol. 2019; 20: 74.

Jonckheer J, Spapen H, Debain A, Demol J, Diltoer M, Costa O, Lanckmans K, Oshima T, Honore PM, Malbrain M, De Waele E. CO2 and O2 removal during continuous veno-venous hemofiltration: a pilot study. BMC Nephrol. 2019; 20: 222.

Gando S, Shiraishi A, Yamakawa K, Ogura H, Saitoh D, Fijishima S, Mayumi T, Kushimoto S, Abe T, Shiino Y, Nakada TA, Tarui T, Hifumi T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Skamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Fujimi S, Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis and Trauma (FORECAST) Study Group. Role of disseminated intravascular coagulation in severe sepsis. Throm Res. 2019; 178: 182-188.

Nakada TA, Takahashi W, Nakada E, Shimada T, Russell JA, Walley KR. Genetic Polymorphisms in Sepsis and Cardiovascular Disease: Do Similar Risk Genes Suggest Similar Drug Targets? Chest 2019; 155: 1260-1271.

Sugiura A, Abe R, Nakayama T, Hattori N, Fujimoto Y, Himi T, Sano K, Oda S, Kobayashi Y. Predictors of successful weaning from veno-arterial extracorporeal membrane oxygenation after coronary revascularization for acute myocardial infarction complicated by cardiac arrest: A retrospective multicenter study. Shock. 2019; 51: 690-697.

Fujishima S, Gando S, Saitoh D, Kushimoto S, Ogura H, Abe T, Shiraishi A, Mayumi T, Sasaki J, Kotani J, Takeyama N, Tsuruta R, Takuma K, Yamashita N, Shiraishi S, Ikeda H, Shiino Y, Tarui T, Nakada TA, Hifumi T, Otomo Y, Okamoto K, Sakamoto Y, Hagiwara A, Masuno T, Ueyama M, Fujimi S, yamakawa K, Umemura Y, JAAM FORECAST ARDS Study Group. Demographics, treatments, and outcomes of acute respiratory distress syndrome: The focused outcomes research in emergency care in acute respiratory distress syndrome, sepsis, and trauma (FORECAST) study. Shock. 2019; 53: 544-549.

Leung AKK, Genga KR, Topchiy E, Cirstea M, Shimada T, Fjell C, Russell JA, Boyd JH, Walley KR. Reduced Proprotein convertase subtilisin/kexin 9 (PCSK9) function increases lipoteichoic acid clearance and improves outcomes in Gram positive septic shock patients. Sci Rep. 2019; 9: 10588.

Kawaguchi R, Nakada TA, Oshima T, Shinozaki M, Nakaguchi T, Haneishi H, Oda S. Optimal pressing strength and time for capillary refilling time. Crit Care. 2019; 23: 4.

Matsumura Y, Matsumoto J, Ito K, Obe H, Kinoshita T, Hayashida K, Funabiki T, Yamakawa K, Kushimoto S, Fujimi S, the Japanese. Endovascular resuscitation and trauma management in the hybrid emergency room system: Ideal solution for surgical, endovascular and radiological trinity. Journal of Endovascular Resuscitation and Trauma Management 2019; 3: 27-31.

Imaeda T, Nakada TA, Abe R, Oda S. Decreased total iron binding capacity upon intensive care unit admission predicts red blood cell transfusion in critically ill patients. Plos One. 2019; 14: e0210067.

Tanaka K, Matsumura Y, Matsumoto J. Prompt procedures to hemodynamically unstable patients with pelvic fractures. Journal of Endovascular Resuscitation and Trauma Management 2019; 3: 11-14.

Takahashi N, Nakada TA, Oda S. Delayed aortic regurgitation due to traumatic pseudoaneurysm of the sinus of Valsalva. Acute Med Surg. 2019; 6: 185-187.

Komindr A, Abe R, Tateishi Y, Takahashi Y, Goto J, Wada K, Furukawa Y, Sugiura A, Imaeda T, Suga N, Hattori N, Oda S. Establishing extracorporeal membrane oxygenation team increased number of patients and improved data recording. J Intensive Care. 2019; 7: 11.

Yamada M, Nakada TA, Nakao S, Hira E, Shinozaki K, Kawaguchi R, Mizushima Y, Matsuoka T. Novel information and communication technology system to improve surge capacity and information management in the initial hospital response to major incidents. The Am J Emerg Med. 2019; 37: 351-355.

Fujiwara K, Abe R, Yasui S, Yokosuka O, Kato N, Oda S. High recovery rate of consciousness by high-volume filtrate hemodiafiltration for fulminant hepatitis. Hepatol Res. 2019; 49: 224-231.

Iwase S, Nakada TA, Hattori N, Takahashi W, Takahashi N, Aizimu T, Yoshida M, Morozane T, Oda S. Interleukin-6 as a diagnostic marker for infection in critically ill patients: A systematic review and meta-analysis. Am J Emerg Med. 2019; 37: 260-265.

Fujishima S, Gando S, Saitoh D, Kushimoto S, Ogura H, Abe T, Shiraishi A, Mayumi T, Sasaki J, Kotani J, Takeyama N, Tsuruta R, Takuma K, Yamashita N, Shiraishi S, Ikeda H, Shiino Y, Tarui T, Nakada TA, Hifumi T, Otomo Y, Okamoto K, Sakamoto Y, Hagiwara A, Masuno T, Ueyama S, Fujimi S, Yamakawa K, Umemura Y. Trends in sepsis care in Japan: comparison of two sepsis cohort studies conducted by the Japanese Association for Acute Medicine. Acute Med Surg. 2019; 6: 425-427.

Yamamoto R, Suzuki M, Hayashida K, Yoshizawa J, Sakurai A, Kitamura N, Tagami T, Nakada TA, Takeda M, Sasaki J, SOS-KANTO 2012 Study Group. Epinephrine during resuscitation of traumatic cardiac arrest and increased mortality: a post hoc analysis of prospective observational study. Scand J Resusc Emerg Med. 2019; 27: e74.

Matsumura Y, Nakada TA, Abe T, Ogura H, Shiraishi A, Kushimoto S, Saitoh D, Fujishima S, Mayumi T, Shiino Y, Tarui T, Hifumi T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Fujimi S, Gando S, On behalf of JAAMFORECAST Study Group. Nighttime and non-business days are not associated with increased risk of in-hospital mortality in patients with severe sepsis in intensive care units in Japan: The JAAM FORECAST study. J Crit Care. 2019; 52: 97-102.

Tomita K, Nakada TA, Oshima T, Oami T, Aizimu T, Oda S. Non-invasive monitoring using photoplethysmography technology. J Clin Monit Comput. 2019; 33: 637-645.

Saito D, Watanabe E, Ashida A, Kato H, Yoshida Y, Nangaku M, Ohtsuka Y, Miyata T, Hattori N, Oda S. Atypical hemolytic uremic syndrome with the p.Ile1157Thr C3 mutation successfully treated with plasma exchange and eculizumab: A case report. Crit Care Explor. 2019; 1: e0008.

Oami T, Coopersmith CM. A venomous relationship: Inflammation, the gut barrier and the STING pathway. EBioMedicine. 2019; 42: 36-37.

2018

Kinoshita T, Yamakawa K, Yoshimura J, Watanabe A, Matsumura Y, Ito K, Ohbe H, Hayashida K, Kushimoto S, Matsumoto J, Fujimi S, Japanese Association for Promotion Committee. First clinical experiences of concurrent bleeding control and intracranial pressure monitoring using a hybrid emergency room system in patients with multiple injuries. World journal of emergency surgery 2018; 13: 56.

Reva VA, Matsumura Y, Samokhvalov IM, Pochatarnik AA, Zheleznyak IS, Mikhailovskaya EK, Morrison JJ. Defining degree of aortic occlusion for partial-REBOA: A computed tomography study on large animals. Injury 2018; 49: 1058-1063.

Sadeghi M, Nilsson KF, Larzon T, Pirouzram A, Toivola A, Skoog P, Idoguchi K, Kon Y, Ishida T, Matsumura Y, Matsumoto J, Reva V, Maszkowski M, Bersztel A, Caragounis E, Falkenberg M, Handolin L, Kessel B, Hebron D, Coccolini F, Ansaloni L, Madursha MJ, Morrison JJ, Horer TM. The use of aortic balloon occlusion in traumatic shock: first report from the ABO trauma registry. European journal of trauma and emergency surgery 2018; 44: 491-501.

Funabiki T, Matsumura Y, Kondo H, Idoguchi K, Matsumoto J, Japanese Society of Diagnostic and Interventional Radiology in Emergency, Critical Care, and Trauma (DIRECT) . Creating an educational program in the endovascular and hybrid intervention; experiences from the Japanese Society of Diagnostic and Interventional Radiology in Emergency, Critical Care, and Trauma (DIRECT). . Journal of Endovascular Resuscitation and Trauma Management 2018;2:10-6.

Fujiwara K, Yasui S, Yokosuka O, Oda S, Kato N. A role of renal replacement therapy for acute liver failure. Hepatology. 2018; 68: 1204.

Matsumura Y, Matsumoto J, Kondo H, Idoguchi K, Ishida T, Okada Y, Kon Y, Oka K, Ishida K, Toyoda Y, Funabiki T, DIRECT-IABO Investigators. Early arterial access for resuscitative endovascular balloon occlusion of the aorta is related to survival outcome in trauma. J Trauma Acute Care Surg. 2018; 85: 507-511.

Achamrah N, Oshima T, Genton L. Innovations in energy expenditure assessment. Curr Opin Clin Nutr Metab Care. 2018; 21: 321-328.

Oami T, Watanabe E, Hatano M, Teratake Y, Fujimura L, Sakamoto A, Ito C, Toshimori K, Swanson PE, Oda S. Blocking liver autophagy accelerates apoptosis and mitochondrial injury in hepatocytes and reduces time to mortality in a murine sepsis model. Shock. 2018; 50: 427-434.

Yazaki M, Oami T, Nakanishi K, Hase R, Watranabe H. A successful salvage therapy with daptomycin and linezolid for right-sided infective endocarditis and septic pulmonary embolism caused by methicillin-resistant Staphylococcus aureus. J Infect Chemother. 2018; 24: 845-848.

Oami T, Oshima T, Hattori N, Teratani A, Honda S, Yoshida T, Oda S. L-carnitine in critically ill patients?a case series study. Renal Replacement Therapy 2018; 4: 13.

Matsumura Y, Matsumoto J, Kondo H, Idoguchi K, Funabiki T, DIRECT-IABO investigators. Partial occlusion, conversion from thoracotomy, undelayed but shorter occlusion: resuscitative endovascular balloon occlusion of the aorta strategy in Japan. Eur J Emerg Med. 2018; 25: 348-354.

Abe T, Ogura H, Shiraishi A, Kushimoto S, Satoh D, Fujishima S, Mayumi T, Shiino Y, Nakada TA, Tarui T, Hifumi T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Fujimi S, Gando S, JAAM FORECAST group. Characteristics, management, and in-hospital mortality among patients with severe sepsis in intensive care units in Japan: the FORECAST study. Crit Care. 2018; 22: 322.

Genga KR, Trinder M, Kong HJ, Li X, Leung AKK, Shimada T, Walley KR, Russell JA, Francis GA, Brunham LR, Boyd JH. CETP genetic variant rs1800777 (allele A) is associated with abnormally low HDL-C levels and increased risk of AKI during sepsis. Sci Rep. 2018; 8: 16764.

Genga KR, Shimada T, Boyd JH, Walley KR, Russell JA. The Understanding and Management of Organism Toxicity in Septic Shock. J Innate Immun. 2018; 10: 502-514.

Shimada A, Terada J, Tsushima K, Tateishi Y, Abe R, Oda S, Kobayashi M, Yamane M, Oto T, Tatsumi K. Veno-venous extracorporeal membrane oxygenation bridged living-donor lung transplantation for rapid progressive respiratory failure with pleuroparenchymal fibroelastosis after allogeneic hematopoietic stem cell transplantation. Respir Investig. 2018; 56: 258-262.

Oami T, Oshima T, Oku R, Nakanishi K. Successful treatment of pulmonary embolism-induced cardiac arrest by thrombolysis and targeted temperature management during pregnancy. Acute Med Surg. 2018; 5: 292-295.

Sunahara S, Watanabe E, Hatano Masahiko, Swanson Paul E, Oami T, Fujimura Lisa, Teratake Youichi, Shimazui T, Lee Chiwei, Oda S. Influence of autophagy on acute kidney injury in a murine cecal ligation and puncture sepsis model. Sci Rep. 2018; 8: 1050.

Fujiwara K, Yasui S, Haga Y, Nakamura M, Yonemitsu Y, Arai M, Kanda T, Oda S, Yokosuka O, Kato N. Early Combination Therapy with Corticosteroid and Nucleoside Analogue Induces Rapid Resolution of Inflammation in Acute Liver Failure Due to Transient Hepatitis B Virus Infection. Intern Med. 2018; 57: 1543-1552.

Kobe Y, Oami T, Hashida T, Tateishi Y. Potential role for emergency physicians with endoscopy training in the treatment of upper gastrointestinal hemorrhage: a retrospective observational study. Acute Med Surg. 2018; 5: 230-235.

Takahashi N, Nakada TA, Oda S. Efficient CO2 removal using extracorporeal lung and renal assist device. J Artif Organs. 2018; 21: 427-434.

Shimazui T, Nakada TA, Fujimura L, Sakamoto A, Hatano M, Oda S. Development of noninvasive in vivo approach to assess vascular permeability in inflammation using fluorescence imaging. Shock. 2018; 50: 729-734.

Matsumura Y, Matsumoto J, Idoguchi K, Kondo H, Ishida T, Kon Y, Tomita K, Ishida K, Hirose T, Umakoshi K, Funabiki T, DIRECT-IABO investigators. Non-traumatic hemorrhage is controlled with REBOA in acute phase then mortality increases gradually by non-hemorrhagic causes: DIRECT-IABO registry in Japan. Eur J Trauma Emerg Surg. 2018; 44: 503-509.

2017

Shimazui T, Matsumura Y, Nakada TA, Oda S.Serum levels of interleukin-6 may predict organ dysfunction earlier than SOFA score.Acute Med Surg. 2017; 4: 255-261

Matsumura Y, Matsumoto J, Kondo H, Idoguchi K, Funabiki T; DIRECT-IABO investigators. Partial occlusion, conversion from thoracotomy, undelayed but shorter occlusion: resuscitative endovascular balloon occlusion of the aorta strategy in Japan. Eur J Emerg Med. Eur J Emerg Med. 2017; 21 [Epub ahead of print]

Suga N, Matsumura Y, Abe R, Hattori N, Nakada TA, Oda S. A safe procedure for connecting a continuous renal replacement therapy device into an extracorporeal membrane oxygenation circuit. J Artif Organs. 2017; 24 [Epub ahead of print]

Oami T, Watanabe E, Hatano M, Sunahara S, Fujimura L, Sakamoto A, Ito C, Toshimori K, Oda S. Suppression of T Cell Autophagy Results in Decreased Viability and Function of T Cells Through Accelerated Apoptosis in a Murine Sepsis Model. Crit Care Med. 2017; 45: e77-e85.

Oshima T, Graf S, Heidegger CP, Genton L, Pugin J, Pichard C. Can calculation of energy expenditure based on CO2 measurements replace indirect calorimetry? Crit Care. 2017; 21: 13

Tanaka K, Nakada TA, Fukuma H, Nakao S, Masunaga N, Tomita K, Matsumura Y, Mizushima Y, Matsuoka T. Development of a novel information and communication technology system to compensate for a sudden shortage of emergency department physicians. Scand J Trauma Resusc Emerg Med. 2017 23;25(1):6

Oshima T, Berger MM, De Waele E, Guttormsen AB, Heidegger CP, Hiesmayr M, Singer P, Wernerman J, Pichard C. Indirect calorimetry in nutritional therapy. A position paper by the ICALIC study group. Clin Nutr. 2017; 36: 651-662

2016

Reva VA, Matsumura Y, Hörer T, Sveklov DA, Denisov AV, Telickiy SY, Seleznev AB, Bozhedomova ER, Matsumoto J, Samokhvalov IM, Morrison JJ. Resuscitative endovascular balloon occlusion of the aorta: what is the optimum occlusion time in an ovine model of hemorrhagic shock? Eur J Trauma Emerg Surg. 2016; 13[Epub ahead of print]

Teeter WA, Matsumoto J, Idoguchi K, Kon Y, Orita T, Funabiki T, Brenner ML, Matsumura Y. Smaller introducer sheaths for REBOA may be associated with fewer complications. J Trauma Acute Care Surg. 2016; 81: 1039-1045.

Hashida T, Nakada TA, Satoh M, Tomita K, Kawaguchi R, Nomura F, Oda S. Proteome analysis of hemofilter adsorbates to identify novel substances of sepsis: a pilot study. J Artif Organs. 2016; 17[Epub ahead of print]

Oshima T, Heidegger CP, Pichard C. Supplemental Parenteral Nutrition Is the Key to Prevent Energy Deficits in Critically Ill Patients. Nutr Clin Pract. 2016; 31: 432-7

Oshima T, Singer P, Pichard C. Parenteral or enteral nutrition: do you have the choice? Curr Opin Crit Care. 2016; 22: 292-8.

Oshima T, Hiesmayr M, Pichard C. Parenteral nutrition in the ICU setting: need for a shift in utilization. Curr Opin Clin Nutr Metab Care. 2016; 19: 144-50.

Kurita T, Nakada TA, Kawaguchi R, Shinozaki K, Abe R, Oda S. Timing and Location of Medical Emergency Team Activation Is Associated with Seriousness of Outcome: An Observational Study in a Tertiary Care Hospital. PLoS One. 2016;11:e0168729.

Matsumura Y, Nakada TA, Abe R. Novel prediction tool for veno-arterial extracorporeal membranous oxygenation in acute myocardial infarction patients. J Thorac Dis 2016; 8: E466-E468

Takahashi W, Nakada TA, Yazaki M, Oda S. Interleukin-6 Levels Act as a Diagnostic Marker for Infection and a Prognostic Marker in Patients with Organ Dysfunction in Intensive Care Units. Shock. [Epub ahead of print]

Matsumura Y, Nakada TA, Shinozaki K, Tagami T, Nomura T, Tahara Y, Sakurai A, Yonemoto N, Nagao K, Yaguchi A, Morimura N; SOS-KANTO 2012 study group. Nighttime is associated with decreased survival and resuscitation efforts for out-of-hospital cardiac arrests: a prospective observational study. Crit Care. 2016; 20: 141.

Nakada T, Takahashi W, Russell JA. Should fever be treated ? In: EVIDENCE-BASED PRACTICE of CRITICAL CARE SECOND EDITION. editor Deutschman CS, Neliganpp PJ. Philadelphia: Elsevier 2016:118-123.

Imaeda T, Nakada TA, Abe R, Tateishi Y, Oda S. Veno-arterial extracorporeal membrane oxygenation for Streptococcus pyogenes toxic shock syndrome in pregnancy. J Artif Organs. 2016; 19: 200-3

Oshima T, Kodama Y, Takahashi W, Hayashi Y, Iwase S, Kurita T, Saito D, Yamaji Y, Oda S. Empiric Antibiotic Therapy for Severe Sepsis and Septic Shock. Surg Infect. 2016; 17: 210-6.

Oshima T, Deutz NE, Doig G, Wischmeyer PE, Pichard C. Protein-energy nutrition in the ICU is the power couple: A hypothesis forming analysis. Clin Nutr. 2016; 35: 968-74

2015

Oshima T, Pichard C. Parenteral nutrition: never say never. Critical Care. 2015; 19: S5

Kawaguchi R, Nakada TA, Oshima T, Abe R, Matsumura Y, Oda S. Reduction of unexpected serious adverse events after introducing medical emergency team. Acute Medicine & Surgery 2015; 2: 244–249.

Matsumura Y, Nakada TA, Hayashi Y, Oshima T, Oda S. Intrahospital transport of mechanically ventilated ICU patients using new equipment attached to a transfer board. Acute Medicine & Surgery 2015;2:219-22

Matsumura Y, Matsumoto J, Kurita T, Oshima T, Hattori N, Toma T, Teeter WA, Oda S. Atraumatic splenic rupture cases presenting with hemorrhagic shock and coagulopathy treated by splenic artery occlusion using a microballoon catheter before splenectomy. J Surg Case Rep 2015; 2015: rjv121.

Kitamura N, Nakada TA, Shinozaki K, Tahara Y, Sakurai A, Yonemoto N, Nagao K, Yaguchi A, Morimura N; SOS-KANTO 2012 Study Group. Subsequent shock deliveries are associated with increased favorable neurological outcomes in cardiac arrest patients who had initially non-shockable rhythms. Crit Care. 2015; 19: 322

Nakada T, Nakao S, Mizushima Y, Matsuoka T. Association between male sex and increased mortality after falls. Acad Emerg Med. 2015; 22:708-13.

Hashida T, Nakada T, Takahashi W, Abe R, Oda S. Extremely severe anaemia in a critically ill patient who declined a blood transfusion. Transfus Med. 2015; 23:195-197.

Nakada TA, Boyd JH, Russell JA, Aguirre-Hernández R, Wilkinson MD, Thair SA,Nakada E, McConechy MK, Fjell CD, Walley KR. VPS13D Gene Variant Is Associated with Altered IL-6 Production and Mortality in Septic Shock. J Innate Immun. 2015;7:545-53.

Shinozaki K, Lampe JW, Wang CH, Yin T, Kim J, Oda S, Hirasawa H, Becker LB. Developing dual hemofiltration plus cardiopulmonary bypass in rodents. J Surg Res 2015; 195:196-203.

Oshima T, Furukawa Y, Kobayashi M, Sato Y, Nihei A, Oda S. Fulfilling caloric demands according to indirect calorimetry may be beneficial for post cardiac arrest patients under therapeutic hypothermia. Resuscitation. 2015; 88: 81-85.

Nakada TA, Russell JA, Boyd JH, Thair SA, Walley KR. Identification of a Nonsynonymous Polymorphism in the SVEP1 Gene Associated With Altered Clinical Outcomes in Septic Shock. Crit Care Med. 2015; 43: 101-108.