業績  

中山 俊憲

2012 | 2011 | 2010 | 2009 | 2008 | 2006 |
| 原著論文| 総説/著書| 国際会議| 国内会議| 受賞 |

原著論文

Fujii‚ S.‚ Motohashi‚ S.‚ Shimizu‚ K.‚ Nakayama‚ T.‚ Yoshiga‚ Y.‚ and Taniguchi‚ M.   Adjuvant activity mediated by iNKT cells.
Semin. Immunol.  2010;  22     97-102


Ishii‚ Y.‚ Motohashi‚ S.‚ Shimizu‚ K.‚ Nakayama‚ T.‚ Taniguchi‚ M.‚ and Fujii‚ S.   Application of NKT cells in immunotherapy.
Curr. Immunol. Rev.  2010;  6     109-115


Nakayama‚ T.‚ and Yamashita‚ M.   The TCR-mediated signaling pathways that control the direction of helper T cell differentiation.
Semin.Immunol.  2010;  22   (5):   303-309


Iwamura‚ C.‚ and Nakayama‚ T.   Role of NKT cells in allergic asthma.
Curr.Opin.Immunol.  2010;  22   (6):   807-813


Onodera‚ A.‚ Yamashita‚ M.‚ Endo‚ Y.‚ Kuwahara‚ M.‚ Tofukuji‚ S.‚ Hosokawa‚ H.‚ Kanai‚ A.‚ Suzuki‚ Y.‚ and Nakayama‚ T.   STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells.
J.Exp.Med  2010;  207     2493-2506


Okita‚ K.‚ Motohashi‚ S.‚ Shinnakasu‚ R.‚ Nagato‚ K.‚ Yamasaki‚ K.‚ Sato‚ Y.‚ Kitamura‚ H.‚ Hijikata‚ A.‚ Yamashita‚ M.‚ Shimizu‚ K.‚ Fujii‚ S.‚ Ohara‚ O.‚ Taniguchi‚ M.‚ Sakaida‚ I.‚ and Nakayama‚ T.   A set of genes associated with the interferon-γ response of lung cancer patients undergoing α-galactosylceramide-pulsed dendritic cell therapy.
Cancer Sci.  2010;  101     2333-2340


Igari‚ H.‚ Segawa‚ S.‚ Watanabe‚ A.‚ Suzuki‚ A.‚ Watanabe‚ M.‚ Sakurai‚ T.‚ Kuroda‚ F.‚ Watanabe‚ M.‚ Tatsumi‚ K.‚ Nakayama‚ M.‚ Nakayama‚ T.‚ Suzuki‚ K.‚ and Sato‚ T.   Immunogenicity of a monovalent pandemic influenza AH1N1 vaccine in health-care workers of a university hospital in Japan.
Microbiol.Immunol.  2010;  5     618-624


Kobayashi‚ K.‚ Tanaka‚ Y.‚ Horiguchi‚ S.‚ Yamamoto‚ S.‚ Nakayama‚ T.‚ Sugimoto‚ A.‚ and Okamoto‚ Y.   The effect of radiotherapy on NKT cells in patients with advanced head and neck cancer.
Cancer Immunol. Immunother  2010;  59     1503-1509


Ichiyanagi‚ T.‚ Imai‚ T.‚ Kajiwara‚ C.‚ Mizukami‚ S.‚ Nakai‚ A.‚ Nakayama‚ T.‚ and Udono‚ H.   Essential role of endogenous heat shock protein 90 of dendritic cells in antigen cross-presentation.
J.Immunol.  2010;  185     2693-2700


Ishio N‚ Kobayashi Y‚ Iwata Y‚ Kitahara H‚ Fukushima K‚ Asano T‚ Nakayama T‚ Kuroda N‚ Komuro I.   Ubiquitous atherosclerosis in coronary arteries without angiographically significant stenosis.
Heart Vessels  2010;  25   (1):   35-40


Suzuki A.‚ Iwamura C.‚ Shinoda K.‚ Tumes J. D.‚ Kimura Y. M.‚ Hosokawa H.‚ Endo Y.‚ Horiuchi S.‚ Tokoyoda K.‚ Koseki H.‚ Yamashita M.‚ and Nakayama T.   Polycomb group gene product Ring1B regulates Th2-driven airway inflammation through the inhibition of Bim-mediated apoptosis of effector Th2 cells in the lung.
J. Immunol.  2010;  184   (8):   4510-4520


Fujimura T.‚ Yonekura S.‚ Taniguchi Y.‚ Horiguchi S.‚ Saito A.‚ Yasueda H.‚ Nakayama T.‚ Takemori T.‚ Taniguchi M.‚ Sakaguchi M.‚ and Okamoto Y.   The induced regulatory T-cell level‚ defined as the proportion of IL10+Foxp3+ cells among CD25+CD4+ leukocytes‚ is an available therapeutic biomarker for sublingual immunotherapy: A preliminary report.
Int. Arch. Allergy Immunol.  2010;  153   (4):   378-387


Suzuki S.‚ Tanaka T.‚ Poyurovsky V. M.‚ Nagano H.‚ Mayama T.‚ Ohkubo S.‚ Lokshin M.‚ Hosokawa H.‚ Nakayama T.‚ Suzuki Y.‚ Sugano S.‚ Sato E.‚ Nagao T.‚ Yokote K.‚ Tatsuno I.‚ and Prives C.   Phosphate activated glutaminase (GLS2)‚ a p53-inducible regulator of glutamine metabolism and reactive oxygen species.
Proc. Natl. Acad. Sci. USA  2010;  107   (16):   7461-7466


Tokoyoda K.‚ Hauser A. E.‚ Nakayama T.‚ and Radbruch A.   Organization of immunological memory by bone marrow stroma.
Nat. Rev. Immunol.  2010;  10     193-200


Tomizawa‚ K.‚ Nagao‚ T.‚ Kusunoki‚ R.‚ Saiga‚ K.‚ Oshima‚ M.‚ Kobayashi‚ K.‚ Nakayama‚ T.‚ Tanokura‚ M.‚ and Suzuki‚ K.   Reduction of MPO-ANCA epitopes in SCG/Kj mice by 15-Deoxyspergualin treatment restricted by IgG2b associated with crescentic glomerulonephritis.
Rheumatology  2010;  49   (7):   1245-1256


Iwata‚ A.‚ Watanabe‚ N.‚ Oya‚ Y.‚ Owada‚ T.‚ Ikeda‚ K.‚ Suto‚ A.‚ Kagami‚ S.‚ Hirose‚ K.‚ Kanari‚ H.‚ Kawashima‚ S.‚ Nakayama‚ T.‚ Taniguchi‚ M.‚ Iwamoto‚ I.‚ and Nakajima‚ H.   Protective roles of B and T lymphocyte attenuator in NKT cell-mediated experimental hepatitis.
J. Immunol.  2010;  184   (1):   127-133


Iwamura‚ C.‚ Shinoda‚ K.‚ Yoshimura‚ M.‚ Watanabe‚ Y.‚ Obata‚ A.‚ and Nakayama‚ T.:   Naringenin chalcone suppresses allergic asthma by inhibiting the type-2 function of CD4 T cells.
Allergology International  2010;  59   (1):   67-73


Nakayama T.‚ Kimura Y.M.   Memory Th1/Th2 cell generation controlled by schnurri-2.
Memory T-Cells  2010;  684     1-10


Hasegawa A‚ Hayashi K‚ Kishimoto H‚ Yang M‚ Tofukuji S‚ Suzuki K‚ Nakajima H‚ Hoffman R‚ Shirai M‚ Nakayama T.   Color-coded real-time cellular imaging of T lymphocyte accumulation and focus formation in mouse asthma model.
J Allergy Clin. Immunol.  2010;  125     461-468


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総説/著書

岩村千秋、中山俊憲   CD4T細胞の機能とCD69   臨床免疫・アレルギ−科  2010;  53     575-582


平崎能郎、岩村千秋、中山俊憲   アレルギー疾患の合併の基礎的考察   臨床免疫・アレルギ−科  2010;  53     583-589


中山俊憲   ぜんそく   別冊がんサポート めんえきサポート  2010;  1     22-23


鈴木茜、中山俊憲   Th2サイトカイン産生制御機構 サイトカインと疾患ーあらたな病態モデルから治療へ   医学のあゆみ  2010;  234     386-393


長谷川明洋、中山俊憲   免疫炎症疾患におけるCD4T細胞の役割:新展開ー抗炎症治療ターゲットとしてのCD69ー   日本臨床免疫学会会誌   2010;  33     189-195


本橋新一郎、中山俊憲   NKT細胞免疫療法   がん免疫療法ー実用化へのチャレンジー  2010;  1     129-134


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国際会議

Nakayama‚ T CD4 T cell memory controlled by Polycomb and Trithorax molecules. 
The 10th Awaji International Forum on Infection and Immunity 2010-9-7 Awaji/Japan


Taniguchi‚ M.‚ Fujii‚ S.‚ Motohashi‚ S.‚ and Nakayama‚ T. NKT cell-targeted adjuvant cell therapy-from basic to clinic. 
14th International Congress of Immunology 2010-8-22 Kobe/Japan


Nakayama‚ T. iNKT cell-based immunotherapy for cancer. 
Corporate Thursday Clinical Immunology Society 2010-5-20 Philadelphia/USA


Sugamata R‚ Nagao T‚ Dobashi H‚ Tomizawa K. Yamamoto K‚ Nakajima N‚ Sato Y‚ Aratani Y‚ Todaka R‚ Oshima M‚ Sata T‚ Kobayashi K‚ Kawachi S‚ Nakayama T‚ Suzuki K. Role of neutrophils and myeloperoxidase in lung injury induced by influenza A/H1N1 (PR-8) infection in mice. 
Annual scientific meeting of the European Society for Clinical Investigation 2010-2-24 Bari/Italy


Suzuki‚ K.‚ Sugamata‚ R.‚ Nagao‚ T.‚ Tomizawa‚ H.‚ Yamamoto‚ K.‚ Nakajima‚ N.‚ Sato‚ Y.‚ Aratani‚ Y.‚ Todaka‚ R.‚ Oshima‚ M.‚ Sata‚ T.‚ Kobayashi‚ K.‚ Kawachi‚ S.‚ Phung‚ T. T. B.‚ Nguyen‚ L.‚ and Nakayama‚ T. Role of neutrophils and myeloperoxidase in severe lung injury in mice with influenza A/H1N1 (PR-8) and in patients with avian flu (H5N1). 
3rd International Bioimaging Symposium 2010-1-18 Okazaki/Japan


Hasegawa‚ A.‚ and Nakayama‚ T. Real-time cellular imaging of T lymphocyte migration in a mouse asthma model. 
3rd International Bioimaging Symposium 2010-1-18 Okazaki/Japan


Nagao T‚ Aratani Y‚ Nakayama T‚ Suzuki K Development of murine crescentic glomerulonephritis model using anti-MPO and anti-LAMP-2 antibodies 
Inflammation Program(炎症制御学セミナー) 2010-1-15 Chiba/Japan


Nakayama‚ T. Dual negative regulation of GATA3 function by Sox4. Adaptive and Innate Immune Responses to Neglected Tropical Diseases Conference 
US-JAPAN Joint Immunology Board&Parastic Disease Panel Conference 2010-1-10 San Diego/USA


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国内会議

Nakayama‚ T.‚ and Motohashi‚ S. iNKT cell based immunotherapy for cancer. 
第69回日本癌学会学術総会 2010-9-22 大阪市


中山俊憲 Epigenetic regulation of GATA3 expression in Th2 cells. 
RCAI International Summer Program 2010 2010-8-17 横浜市


Ishibashi‚ F.‚ Motohashi‚ S.‚ Taniguchi‚ M.‚ Yoshino‚ I.‚ and Nakayama‚ T. Trans-bronchial injection of alpha-GalCer-pulsed APCs in patients with advanced or recurrent lung cancer. 
第14回日本がん免疫学会総会 2010-7-22 熊本


中山俊憲 NKT細胞免疫系を標的にした免疫細胞治療 
第19回日本癌病態治療研究会 2010-6-30 東京都


中山俊憲 Immunotherapy 
NZ-RIKEN-CHIBA Joint Workshop "Recent advances in immune regulation and immunotherapy" 2010-6-14 横浜市


中山俊憲 免疫記憶、ポリコームとトライソラックスによる制御 
第4回日本エピジェネティクス研究会 2010-5-28 米子市


中山俊憲 免疫記憶:ポリコームとトライソラックスによる制御 
平成21年度千葉大学COEスタートアッププログラム「発生システムの分子基盤解析拠点の構築」 第1回「発生システム」シンポジウム 2010-2-15 千葉市


本橋新一郎、石橋史博、谷口克、中山俊憲、吉野一郎 NKT cell-based Immunotherapy for lung cancer 
第48回日本癌治療学会学術集会 2010-10-29 京都


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受賞

2010-9-21
 日本免疫学会第5回研究奨励賞 日本免疫学会  常世田好司

2010-9-2
 若手科学者の為の研究員奨励賞 Robert-Koch 財団(ドイツ) 常世田 好司

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