業績
小室 一成| 2012 | 2011 | 2010 | 2009 | 2008 |
| 原著論文| 総説/著書| 国際会議| 国内会議| 特許| 受賞 |
原著論文
Kadohira T‚ Kobayashi Y‚ Niitsuma Y‚ Imamaki M‚ Komuro I. Global ST-segment elevation associated with impending cardiac rupture during diagnostic cardiac catheterization.
Int Heart J. 2009; 50 (4): 539-542
Sugimoto K‚ Kobayashi Y‚ Kuroda N‚ Komuro I. Cost analysis of sirolimus-eluting stents in the Japanese health insurance system.
Int Heart J 2009; 50 (6): 723-730
Asano T‚ Kobayashi Y‚ Fukushima K‚ Iwata Y‚ Kitahara H‚ Ishio N‚ Nakayama T‚ Kuroda N‚ Komuro I. Effect of balloon inflation time on expansion of sirolimus-eluting stent.
Heart Vessels 2009; 24 (5): 335-339
Saito R‚ Kaneko E‚ Tanaka Y‚ Honda K‚ Matsuda T‚ Baba A‚ Komuro I‚ Kita S‚ Iwamoto T‚ Takano Y. Involvement of Na+/Ca2+ exchanger in pentylenetetrazol-induced convulsion by use of Na+/Ca2+ exchanger knockout mice.
Biol Pharm Bull. 2009; 32 (11): 1928-1930
Wakatsuki Y‚ Funabashi N‚ Mikami Y‚ Shiina Y‚ Kawakubo M‚ Takahashi M‚ Yajima R‚ Uehara M‚ Takaoka H‚ Komuro I. Left atrial compensatory function in subjects with early stage primary hypertension assessed by using left atrial volumetric emptying fraction acquired by transthoracic echocardiography.
Int J Cardiol. 2009; 136 (3): 363-367
Shiina Y‚ Funabashi N‚ Lee K‚ Daimon M‚ Sekine T‚ Kawakubo M‚ Takahashi M‚ Yajima R‚ Tanabe N‚ Kuriyama T‚ Komuro I. Right atrium contractility and right ventricular diastolic function assessed by pulsed Tissue Doppler Imaging can predict brain natriuretic peptide in adults with acquired pulmonary hypertension.
Int J Cardiol. 2009; 135 (1): 53-59
Takano H‚ Komuro I. Peroxisome proliferator-activated receptor gamma and cardiovascular diseases.
Circ J. 2009; 73 (2): 214-220
Ichimoto E‚ Jo K‚ Kobayashi Y‚ Inoue T‚ Nakamura Y‚ Kuroda N‚ Miyazaki A‚ Komuro I. Prognostic significance of cystatin C in patients with ST-elevation myocardial infarction.
Circ J. 2009; 73 (9): 1669-1673
Tamura A‚ Ogura T‚ Uemura H‚ Reien Y‚ Kishimoto T‚ Nagai T‚ Komuro I‚ Miyazaki M‚ Nakaya H. Effects of antiarrhythmic drugs on the hyperpolarization-activated cyclic nucleotide-gated channel current.
J Pharmacol Sci. 2009; 110 (2): 150-159
Mikami Y‚ Sakuma H‚ Nagata M‚ Ishida M‚ Kurita T‚ Komuro I‚ Ito M. Relation between signal intensity on T2-weighted MR images and presence of microvascular obstruction in patients with acute myocardial infarction.
AJR Am J Roentgenol. 2009; 193 (4): W321-326
Inokuchi Y‚ Shimazawa M‚ Nakajima Y‚ Komuro I‚ Matsuda T‚ Baba A‚ Araie M‚ Kita S‚ Iwamoto T‚ Hara H. A Na+/Ca2+ exchanger isoform‚ NCX1‚ is involved in retinal cell death after N-methyl-D-aspartate injection and ischemia-reperfusion.
J Neurosci Res. 2009; 87 (4): 906-917
Shiina Y‚ Funabashi N‚ Lee K‚ Murayama T‚ Nakamura K‚ Wakatsuki Y‚ Daimon M‚ Komuro I. Acute effect of oral flavonoid-rich dark chocolate intake on coronary circulation‚ as compared with non-flavonoid white chocolate‚ by transthoracic Doppler echocardiography in healthy adults.
Int J Cardiol. 2009; 131 (3): 424-429
Kawata T‚ Daimon M‚ Hasegawa R‚ Teramoto K‚ Toyoda T‚ Sekine T‚ Yamamoto K‚ Uchida D‚ Himi T‚ Yoshida K‚ Komuro I. Effect of angiotensin-converting enzyme inhibitor on serum asymmetric dimethylarginine and coronary circulation in patients with type 2 diabetes mellitus.
Int J Cardiol. 2009; 132 (2): 286-288
Ogihara T‚ Kikuchi K‚ Matsuoka H‚ Fujita T‚ Higaki J‚ Horiuchi M‚ Imai Y‚ Imaizumi T‚ Ito S‚ Iwao H‚ Kario K‚ Kawano Y‚ Kim-Mitsuyama S‚ Kimura G‚ Matsubara H‚ Matsuura H‚ Naruse M‚ Saito I‚ Shimada K‚ Shimamoto K‚ Suzuki H‚ Takishita S‚ Tanahashi N‚ Tsuchihashi T‚ Uchiyama M‚ Ueda S‚ Ueshima H‚ Umemura S‚ Ishimitsu T‚ Rakugi H; Japanese Society of Hypertension Committee. The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2009).
Hypertens Res. 2009; 32 (1): 3-107
Akazawa H‚ Yasuda N‚ Komuro I. Mechanisms and functions of agonist-independent activation in the angiotensin II type 1 receptor.
Mol Cell Endocrinol. 2009; 302 (2): 140-147
Ikeda H‚ Shiojima I‚ Ozasa Y‚ Yoshida M‚ Holzenberger M‚ Kahn CR‚ Walsh K‚ Igarashi T‚ Abel ED‚ Komuro I. Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy.
J Mol Cell Cardiol. 2009; 47 (5): 664-675
Ito K‚ Akazawa H‚ Tamagawa M‚ Furukawa K‚ Ogawa W‚ Yasuda N‚ Kudo Y‚ Liao CH‚ Yamamoto R‚ Sato T‚ Molkentin JD‚ Kasuga M‚ Noda T‚ Nakaya H‚ Komuro I. PDK1 coordinates survival pathways and beta-adrenergic response in the heart.
Proc Natl Acd Sci U S A. 2009; 106 (21): 8689-8694
Matsuura K‚ Honda A‚ Nagai T‚ Fukushima N‚ Iwanaga K‚ Tokunaga M‚ Shimizu T‚ Okano T‚ Kasanuki H‚ Hagiwara N‚ Komuro I. Transplantation of cardiac progenitor cells ameliorates cardiac dysfunction after myocardial infarction in mice.
J Clin Invest. 2009; 119 (8): 2204-2217
Minamino T‚ Orimo M‚ Shimizu I‚ Kunieda T‚ Yokoyama M‚ Ito T‚ Nojima A‚ Nabetani A‚ Oike Y‚ Matsubara H‚ Ishikawa F‚ Komuro I. A crucial role for adipose tissue p53 in the regulation of insulin resistance.
Nat Med 2009; 15 (9): 1082-1087
Yoshida M‚ Shiojima I‚ Ikeda H‚ Komuro I. Chronic doxorubicin cardiotoxicity is mediated by oxidative DNA damage-ATM-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of Rac1 activity
J. Mole. Cell. Cardiol. 2009; 47 (5): 698-705
Qin Y‚ Yasuda N‚ Akazawa H‚ Ito K‚ Kudo Y‚ Liao CH‚ Yamamoto R‚ Miura SI‚ Saku K‚ Komuro I. Multivalent ligand-receptor interactions elicit inverse agonist activity of AT(1) receptor blockers against stretch-induced AT(1) receptor activation.
Hypertens Res. 2009; 32 (10): 875-883
Otsuka K‚ Terasaki F‚ Ikemoto M‚ Fujita S‚ Tsukada B‚ Katashima T‚ Kanzaki Y‚ Sohmiya K‚ Kono T‚ Toko H‚ Fujita M‚ Kitaura Y. Suppression of inflammation in rat autoimmune myocarditis by S100A8/A9 through modulation of the proinflammatory cytokine network.
Eur J Heart Fail 2009; 11 (3): 229-237
Kayama Y‚ Minamino T‚ Toko H‚ Sakamoto M‚ Shimizu I‚ Takahashi H‚ Okada S‚ Tateno K‚ Moriya J‚ Yokoyama M‚ Nojima A‚ Yoshimura M‚ Egashira K‚ Aburatani H‚ Komuro I. Cardiac 12/15 lipoxygenase-induced inflammation is involved in heart failure
J Exp Med. 2009; 206 (7): 1565-1574
Kitahara H‚ Kobayashi Y‚ Takebayashi H‚ Fujimoto Y‚ Nakamura Y‚ Kuroda N‚ Himi T‚ Miyazaki A‚ Haruta S‚ Komuro I. Re-restenosis and target lesion revascularization after treatment of sirolimus-eluting stent restenosis.
Circ J. 2009; 73 (5): 867-871
Takano H‚ Komuro I. G-CSF therapy for acute myocardial infarction: Studies of animal experiments give valuable hints to clinical trials.
Int J Cardiol. 2009; 135 (1): 115-116
Wakatsuki Y‚ Funabashi N‚ Mikami Y‚ Shiina Y‚ Kawakubo M‚ Takahashi M‚ Yajima R‚ Uehara M‚ Takaoka H‚ Komuro I. Left atrial compensatory function in subjects with early stage primary hypertension assessed by using left atrial volumetric emptying fraction acquired by transthoracic echocardiography.
Int J Cardiol. 2009; 136 (3): 363-367
Shiina Y‚ Funabashi N‚ Teramoto K‚ Uehara M‚ Takaoka H‚ Mikami Y‚ Takahashi A‚ Saito M‚ Daimon M‚ Lee K‚ Kawakubo M‚ Sekine Y‚ Takahashi M‚ Yajima R‚ Tani A‚ Komuro I. Suitable solutions for reconstituting the ultrasound contrast agent "Levovist" used in contrast echocardiogram: In vitro and in vivo evaluation of the influence of osmotic pressure.
Int J Cardiol. 2009; 136 (3): 335-340
Sugimoto K‚ Kobayashi Y‚ Miyahara H‚ Kuroda N‚ Funabashi N‚ Komuro I. Early Stent Thrombosis Because of Stent Dislodgement in a Coronary Artery Aneurysm.
Circ J. 2009; 73 (9): 1759-1761
Nakayama T‚ Kobayashi Y‚ Takano H‚ Kuroda N‚ Hiroshima K‚ Komuro I. Silent Very Late Thrombotic Occlusion of Sirolimus-Eluting Stent Confirmed by Directional Coronary Atherectomy.
Circ J. 2009; 73 (9): 1762-1764
Kitahara H‚ Kobayashi Y‚ Takebayashi H‚ Nakamura Y‚ Kuroda N‚ Miyazaki A‚ Haruta S‚ Komuro I. Angiographic patterns of restenosis after sirolimus-eluting stent implantation.
Circ J. 2009; 73 (3): 508-511
Akazawa H‚ Komuro I. Change can happen" by PKA: proteasomes in in vivo hearts.
J Mol Cell Cardiol. 2009; 46 (4): 445-447
Orimo M‚ Minamino T‚ Miyauchi H‚ Tateno K‚ Okada S‚ Moriya J‚ Komuro I. Protective Role of SIRT1 in Diabetic Vascular Dysfunction.
Arterioscler Thromb Vasc Biol. 2009; 29 (6): 889-894
Shiina Y‚ Funabashi N‚ Lee K‚ Daimon M‚ Sekine T‚ Kawakubo M‚ Sekine Y‚ Takahashi M‚ Yajima R‚ Wakatsuki Y‚ Tanabe N‚ Kuriyama T‚ Komuro I. Doppler imaging predicts cardiac events in chronic pulmonary thromboembolism.
Int J Cardiol. 2009; 133 (2): 167-172
Hama Y‚ Funabashi N‚ Ueda M‚ Kanaeda T‚ Uehara M‚ Nakamura K‚ Murayama T‚ Mikami Y‚ Takaoka H‚ Kawakubo M‚ Lee K‚ Takano H‚ Komuro I. Images in cardiovascular medicine. Right-sided heart wall thickening and delayed enhancement caused by chronic active myocarditis complicated by sustained monomorphic ventricular tachycardia.
Circulation 2009; 119 (6): e200-203
Moriya J‚ Minamino T‚ Tateno K‚ Shimizu N‚ Sato Y‚ Kuwabara Y‚ Saito Y‚ Komuro I. Long-term outcome of therapeutic neovascularization using peripheral blood mononuclear cells for limb ischemia.
Circ Cardiovasc Intervent. 2009; 2 (3): 245-254
総説/著書
舘野馨‚ 南野徹‚ 小室一成 「末梢血単核球細胞移植における血管再生治療とそのメカニズム」 遺伝子医学MOOK13号 2009; inpress
小室一成‚ 長谷川洋‚ 森野知樹‚ 舘野馨‚ 小林欣夫‚ 上田希彦 主要内科疾患投薬処方スタンダード・循環器疾患処方例 医歯薬出版株式会社 2009;
吉田賢司‚ 小室一成 抗癌剤による心筋症とβ遮断薬。β遮断薬のすべて第3版 先端医学社 2009;
東口治弘‚ 小室一成 心不全発症の分子機構 総合臨床 2009; 58 563-568
舘野馨‚ 森谷純治‚ 横山真隆‚ 堅田明美‚ 南野徹‚ 小室一成 血管再生治療における骨格筋再生の役割 再生医療（日本再生医療学会雑誌） 2009; 8 (1): 67-73
舘野馨‚ 南野徹‚ 小室一成 虚血肢に対する細胞移植治療 ― 現状と問題点 病理と臨床（文光堂） 2009; 27 (4): 348-353
国際会議
Komuro I Wnt signaling regulates cardiomyocyte differentiation and cardiac remodeling
Advances in heart development:from molecules to cures 2009-9-28 Nice/France
Yoshida M‚ Shiojima I‚ Ikeda H‚ Komuro I. Pitavastatin attenuates doxorubicin-induced cardiotoxicity through the inhibition of oxidative stress-DNA damage-ATM-p53 pathway.
Basic Cardiocascular Science 2009 2009-7-20 Las Vegas/U.S.A.
Toko‚ H. ER Stress-Response Transcription Factor ATF6 Plays a Critical Role in Maintaining Cardiac Function under Physiological and Pathological Conditions
6th Annual Symposium of the American Heart Association’s Council on Basic Cardiovascular Sciences 2009-7-20 Las Vegas/USA
Komuro I Zhongshan Lecture
The Role of Statin in the Treatment of Heart Failure 2009-12-7 Shanghai/China
Komuro I SIRIC International Forum 2009: Theme: Imaging for Shedding light to Atherosclerosis
Senescenec as a cause of atherosclerosis and therapeutic angiogenesis using peripheral blood mononuclear cells 2009-12-11 Seoul/Korea
Tateno K‚ Minamino T‚ Komuro I. Notch Signaling in Intrinsic Stem Cell is a Prerequisite for Therapeutic Angiogenesis
Scientific Session 2010 American Heart Association 2009-11-14 Orlando/USA
Komuro I The Third International Conference on Cell Therapy(IRICT)
Long-Term Outcome of Therapeutic Neovascularization Using Peripheral Blood Mononuclear Cells for Limb Ischemia 2009-11-12 Seoul/Korea
国内会議
伊藤薫 心房細動発症における肥満細胞浸潤の役割
千葉大学グローバルＣＯＥプログラムリトリート2009 2009-9-5 千葉
伊藤薫 PDK1による心筋の生存と機能の維持機構
第15回 成人病の病因･病態の解明に関する研究会 2009-7-4 軽井沢
舘野馨‚ 清水直美‚ 南野徹‚ 小室一成 血管再生治療の細胞ソース
第57回日本輸血細胞治療学会総会 2009-5-28 さいたま
伊藤薫 PDK1は心筋でのβ受容体反応と細胞生存に必須である
千葉心肥大研究会 2009-5-22 千葉
森谷純治‚ 南野徹‚ 小室一成 糖尿病モデルマウスの血管新生障害における血管制御分子Semaphorin3Eの役割
第46回日本臨床分子医学会学術集会 2009-4-12 東京
伊藤薫‚ 赤澤宏‚ 玉川正次‚ 小川渉‚ 野田哲男‚ 春日正人‚ 中谷晴昭‚ 小室一成 PDK1による心筋の生存と機能の維持機構
第3回Cardio-Diabetes研究会 2009-3-7 東京
吉田賢司‚ 塩島一朗‚ 池田弘之‚ 小室一成 Pitavastatin attenuates doxorubicin-induced cardiotoxicity through the inhibition of oxidative stress-DNA damage-ATM-p53 pathway.
第73回日本循環器学会総会・学術集会 2009-3-20 大阪
Moriya J‚ Minamino T‚ Tateno K‚ Orimo M‚ Komuro I. A pathological role of Semaphorin3E/PlexinD1 in impaired angiogenesis of diabetes.
第73回日本循環器学会総会・学術集会 2009-3-20 大阪
東口治弘‚ 小室一成 ER stress-response Transcriptional Factor ATF6 Plays a Critical Role in Maintaining Cardiac Function under Physiological and Pathological Conditions.
第73回日本循環器学会総会・学術集会 2009-3-20 大阪
東口治弘‚ 南野徹‚ 小室一成 小胞体ストレス応答を制御する転写因子ATF6の心臓における役割
第5回宮崎サイエンスキャンプ 2009-2-20 宮崎
小室 一成 心血管疾患発症抑制を目指した糖尿病治療戦略
第23回日本冠疾患学会学術集会 2009-12-19 大阪市
小室 一成 心不全の新しい発症機序と再生治療
第287回日本内科学会九州地方会・第40回日本内科学会九州支部生涯教育講演会 2009-11-1 福岡市
小室 一成 スタチンの心不全・心房細動に及ぼす効果
第13回日本心不全学会学術集会 モーニングセミナー 2009-10-30 福岡市
特許
２００９−０６７０２１ ノッチシグナルを利用した虚血組織再生方法
舘野 馨‚ 南野 徹 日本
2009-3-18
受賞
2009-4-13
第12回日本臨床分子医学会 学術奨励賞 日本臨床分子医学会 森谷 純治
