業績
小原 收| 2012 | 2011 | 2010 | 2009 | 2008 |
| 原著論文| 国際会議| 国内会議 |
原著論文
Endoh M‚ Endo TA‚ Endoh T‚ Isono K‚ Sharif J‚ Ohara O‚ Toyoda T‚ Ito T‚ Eskeland R‚ Bickmore WA‚ Vidal M‚ Bernstein BE‚ Koseki H. Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity.
PLoS Genet. 2012; 8 (7): e1002774-
Hori T‚ Ohnishi H‚ Teramoto T‚ Tsubouchi K‚ Naiki T‚ Hirose Y‚ Ohara O‚ Seishima M‚ Kaneko H‚ Fukao T‚ Kondo N. Autosomal-Dominant Chronic Mucocutaneous Candidiasis with STAT1-Mutation can be Complicated with Chronic Active Hepatitis and Hypothyroidism.
J Clin Immunol 2012; in press
Kaji T‚ Ishige A‚ Hikida M‚ Taka J‚ Hijikata A‚ Kubo M‚ Nagashima T‚ Takahashi Y‚ Kurosaki T‚ Okada M‚ Ohara O‚ Rajewsky K‚ Takemori T. Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.
J Exp Med. 2012; in press
Nakaoka H‚ Kanegane H‚ Taneichi H‚ Miya K‚ Yang X‚ Nomura K‚ Takezaki S‚ Yamada M‚ Ohara O‚ Kamae C‚ Imai K‚ Nonoyama S‚ Wada T‚ Yachie A‚ Hershfield MS‚ Ariga T‚ Miyawaki T. Delayed onset adenosine deaminase deficiency associated with acute disseminated encephalomyelitis.
Int J Hematol. 2012; 95 (6): 692-696
Mohammadzadeh I‚ Yeganeh M‚ Aghamohammadi A‚ Parvaneh N‚ Behniafard N‚ Abolhassani H‚ Tabassomi F‚ Hemmat M‚ Kanegane H‚ Miyawaki T‚ Ohara O‚ Rezaei N. Severe primary antibody deficiency due to a novel mutation of micro heavy chain.
J Investig Allergol Clin Immunol. 2012; 22 (1): 78-79
Tofukuji S‚ Kuwahara M‚ Suzuki J‚ Ohara O‚ Nakayama T‚ Yamashita M. Identification of a New Pathway for Th1 Cell Development Induced by Cooperative Stimulation with IL-4 and TGF-β.
Immunol. 2012; 188 (10): 4846-4857
Suri D‚ Singh S‚ Rawat A‚ Gupta A‚ Kamae C‚ Honma K‚ Nakagawa N‚ Imai K‚ Nonoyama S‚ Oshima K‚ Mitsuiki N‚ Ohara O‚ Bilhou-Nabera C‚ Proust A‚ Ahluwalia J‚ Dogra S‚ Saikia B‚ Minz RW‚ Sehgal S. Clinical profile and genetic basis of Wiskott-Aldrich syndrome at Chandigarh‚ North India.
Asian Pac J Allergy Immunol. 2012; 30 (1): 71-78
Takezaki S‚ Yamada M‚ Kato M‚ Park MJ‚ Maruyama K‚ Yamazaki Y‚ Chida N‚ Ohara O‚ Kobayashi I‚ Ariga T. Chronic Mucocutaneous Candidiasis Caused by a Gain-of-Function Mutation in the STAT1 DNA-Binding Domain.
J Immunol. 2012; In press
Fukaya T‚ Murakami R‚ Takagi H‚ Sato K‚ Sato Y‚ Otsuka H‚ Ohno M‚ Hijikata A‚ Ohara O‚ Hikida M‚ Malissen B‚ Sato K. Conditional ablation of CD205+ conventional dendritic cells impacts the regulation of T-cell immunity and homeostasis in vivo.
Proc Natl Acad Sci U S A. 2012; In press
Mizuno T‚ Sakai H‚ Nishikomori R‚ Oshima K‚ Ohara O‚ Hata I‚ Shigematsu Y‚ Ishige T‚ Tamura K‚ Arakawa H. Novel mutations of MVK gene in Japanese family members affected with hyperimmunoglobulinemia D and periodic fever syndrome.
Rheumatol Int. 2012; in press
Takagi S‚ Saito Y‚ Hijikata A‚ Tanaka S‚ Watanabe T‚ Hasegawa T‚ Mochizuki S‚ Kunisawa J‚ Kiyono H‚ Koseki H‚ Ohara O‚ Saito T‚ Taniguchi S‚ Shultz LD‚ Ishikawa F. Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation.
Blood. 2012; 119 (12): 2768-2777
Izawa K‚ Hijikata A‚ Tanaka N‚ Kawai T‚ Saito MK‚ Goldbach-Mansky R‚ Aksentijevich I‚ Yasumi T‚ Nakahata T‚ Heike T‚ Nishikomori R‚ Ohara O. Detection of Base Substitution-Type Somatic Mosaicism of the NLRP3 Gene with >99.9% Statistical Confidence by Massively Parallel Sequencing.
DNA Res. 2012; 19 (2): 143-152
国際会議
Osamu Ohara Integra1ve Medical Sciences at RIKEN RCAI: to understand the process of disease development
Australia-Japan workshop on biomedical breakthroughs and systems biology 2012-10-16 Tokyo/Japan
国内会議
Mai Yamagishi‚ Yoshitaka Shirasaki‚ Nanako Shimura‚ Nobutake Suzuki‚ Osamu Ohara マクロファージ細胞株におけるLPS 活性化時の遺伝子発現の細胞間ゆらぎに細胞間相互作用が与える影響 Effects of the cell-cell communication on the populational variability of mRNA levels among clonal macrophages after LPS stimulation
第50回日本生物物理学会年会 The 50th Annual Meeting of the Biophysical Society of Japan 2012-9-22 名古屋市
Yoshitaka Shirasaki‚ Nanako Shimura‚ Nobutake Suzuki‚ Kazushi Izawa‚ Asahi Nakahara‚ Mai Yamagishi‚ Yoshie Harada‚ Shuichi Shouji‚ Ryuta Nishikomori‚ Osamu Ohara 炎症時におけるヒト単球サイトカイン分泌のライブセルイメージング Live-cell secretion imaging assay of the inflammatory cytokine from human monocytes
第50回日本生物物理学会年会 The 50th Annual Meeting of the Biophysical Society of Japan 2012-9-22 名古屋市
桑原誠、鈴木淳平、 小原收、中山俊憲、 山下政克 腫瘍抑制因子MeninによるCD4 T細胞免疫老化の制御
Kyoto T Cell Conference 2012-7-6 京都市
鈴木淳平、桑原誠、 今村匡志、加藤文法、小原收、山下政克 SH-2251はIL-5遺伝子座ヒストンH3K4メチル化の阻害を介してIL-5産生Th2細胞分化を阻害する
Kyoto T Cell Conference 2012-7-6 京都市
小原 收 先進ゲノミクスの疾患研究における展開
第54回日本小児神経学会総会 2012-5-17 札幌市
