Research Achievements

Koutaro Yokote

2012 | 2011 | 2010 |
| Papers| Books| International Conferences |

Papers

Yamada Y‚ Sawai S‚ Misawa S‚ Kanai K‚ Shibuya K‚ Mori M‚ Moriya J‚ Sogawa K‚ Yamamoto H‚ Beppu M‚ Taniguchi J‚ Nakaseko C‚ Nomura F‚ Kuwabara S   Multiple angiogenetic factors are upregulated in POEMS syndrome
Ann Hematol  2012;  in press    


Oshima K‚ Kanda Y‚ Nanya Y‚ Tanaka M‚ Nakaseko C‚ Yano S‚ Fujisawa S‚ Fujita H‚ Yokota A‚ Takahashi S‚ Kanamori H‚ Okamoto S for the Kanto Study Group for Cell Therapy (KSGCT)   Allogeneic hematopoietic stem cell transplantation for patients with mildly reduced renal function as defined based on creatinine clearance before transplantation
Ann Hematol  2012;  in press    


Kitazono-Saitoh M‚ Takiguchi Y‚ Kitazono S‚ Ashinuma H‚ Kitamura A‚ Tada Y‚ Kurosu K‚ Sakaida E‚ Sekine I‚ Tanabe N‚ Tagawa M‚ Tatsumi K   Interaction and cross-resistance of cisplatin and pemetrexed in malignant pleural mesothelioma cell lines.
Oncol Rep  2012;  28   (1):   33-40


Ashinuma H‚ Takiguchi Y‚ Kitazono S‚ Kitazono-Saitoh M‚ Kitamura A‚ Chiba T‚ Tada Y‚ Kurosu K‚ Sakaida E‚ Sekine I‚ Tanabe N‚ Iwama A‚ Yokosuka O‚ Tatsumi K   Antiproliferative action of metformin in human lung cancer cell lines
Oncol Rep  2012;  28   (1):   8-14


Shunichiro Onishi‚ Minoru Takemoto‚ Emiko Okabe‚ Takahiro Ishikawa‚ Ryouichi Ihibashi‚ Peng He‚ Kazuki Kobayashi‚ Masaki Fujimoto‚ Harukiyo Kawamura‚ Koutaro Yokote   Japanese diabetic patients with Werner syndrome exhibit high incidence of cancer.
Acta Diabetologica  2012;  in press    


Okabe E‚ Takemoto M‚ Onishi S‚ Ishikawa T‚ Ishibashi R‚ He P‚ Kobayashi K‚ Fujimoto M‚ Kawamura H‚ Yokote K. J   Incidence and characteristics of metabolic disorders and vascular complications in individuals with Werner syndrome in Japan.
J Am Geriatr Soc  2012;  60     997-998


Onishi S‚ Takemoto M‚ Ishikawa T‚ Okabe E‚ RIshibashi R‚ He P‚ Kobayashi K‚ Fujimoto M‚ Kawamura H‚ Yokote K‚   Japanese diabetic patients with Werner syndrome exhibit high incidence of cancer
Acta Diabetologica  2012;  in press    


Mezawa M‚ Takemoto M‚ Onishi S‚ Ishibashi R‚ Ishikawa T‚ Yamaga M‚ Fujimoto M‚ Okabe E‚ He P‚ Kobayashi K‚ Yokote K   The reduced form of coenzyme Q10 improves glycemic control in patients with type 2 diabetes.
BioFactors  2012;  in press    


Kitamoto¡¡T‚ Takemoto M ‚ Fujimoto M‚ Ishikawa T‚ Onishi S‚ Okabe E‚ Ishibashi R‚ Kobayashi K‚ Kawamura H‚ Yokote K   Sitagliptin successfully ameliorates glycemic control in a Werner’s syndrome with diabetes mellitus.
Diabetes Care  2012;  in press    


Tsuyoshi Matsumoto‚ Kenichi Sakurai‚ Asami Tanaka‚ Takayuki Ishibashi‚ Kaori Tachibana‚ Ko Ishikawa‚ Koutaro Yokote.   The anti-ulcer agent‚ irsogladine‚ increases insulin secretion by MIN6 cells
European Journal of Pharmacology  2012;  685     213-217


Mariko Harada-Shiba‚ Hidenori Arai‚ Shinichi Oikawa‚ Takao Ohta‚ Tomoo Okada‚ Tomonori Okamura‚ Atsushi Nohara‚ Hideaki Bujo‚ Koutaro Yokote‚ Akihiko Wakatsuki‚ Shun Ishibashi‚ Shizuya Ya‚ashita   Guidelines for the Management of Familial Hypercholesterolemia
J Atheroscler Thromb  2012;  in press    


Sakai S‚ Nakaseko C‚ Takeuchi M‚ Ohwada C‚ Shimizu N‚ Tsukamoto S‚ Kawaguchi T‚ Jiang M‚ Sato Y‚ Ebinuma H‚ Yokote K‚ Iwama A‚ Fukamachi I‚ Schneider WJ‚ Saito Y‚ Bujo H   Circulating soluble LR11/SorLA levels are highly increased and ameliorated by chemotherapy in acute leukemias
Clinica Chimica Acta  2012;  in press    


Shimizu N‚ Sakaida E‚ Ohwada C‚ Takeuchi M‚ Kawaguchi T‚ Tsukamoto S‚ Sakai S‚ Takeda Y‚ Sugita Y‚ Yokote K‚ Iseki T‚ Isose S‚ Kanai K‚ Misawa S‚ Kuwabara S‚ Nakaseko C   Mobilization of peripheral blood stem cells in poor mobilizers with POEMS syndrome using G-CSF with plerixafor
Bone Marrow Transplant  2012;     


Shimizu N‚ Nakaseko C‚ Sakaida E‚ Ohwada C‚ Takeuchi M‚ Tanaka S‚ Muto T‚ Kawaguchi T‚ Tsukamoto S‚ Sakai S‚ Takeda Y‚ Abe D‚ Yokote K‚ Iseki T‚ Kanai K‚ Misawa S‚ Kuwabara S   Factors associated with the efficiency of peripheral blood stem cell harvest in patients with POEMS syndrome undergoing autologous peripheral blood stem cell transplantation
Bone Marrow Transplant  2012;     


Kanai K‚ Sawai S‚ Sogawa K‚ Mori M‚ Misawa S‚ Shibuya K‚ Isose S‚ Fujimaki Y‚ Sekiguchi Y‚ Nasu S‚ Nakaseko C‚ Takano S‚ Yoshitomi H‚ Miyazaki M‚ Nomura F‚ Kuwabara S (*equally contributed to the study)   Markedly upregulated interleukin-12 as a novel biomarker in POEMS syndrome
Neurology  2012;  in press    


Takeuchi M‚ Nakaseko C‚ Ohwada C‚ Sato Y‚ Ohashi K‚ Kakihana K‚ Mori T‚ Aisa Y‚ Kanda Y‚ Takahashi S‚ Yokota A‚ Kawaguchi T‚ Saitoh T‚ Hatsumi N‚ Taguchi J‚ Takasaki H‚ Kanamori H‚ Maruta A‚ Sakamaki H‚ and Okamoto S   Allogeneic hematopoietic stem cell transplantation for primary and secondary myelofibrosis: a retrospective‚ multicenter study of the Kanto Study Group for Cell Therapy (KSGCT)
J Hematopoietic Cell Transplant  2012;  in press    


Ohnishi K‚ Nakaseko C‚ Takeuchi J‚ Fujisawa S‚ Nagai T‚ Yamazaki H‚ Tauchi T‚ Imai K‚ Mori N‚ Yagasaki F‚ Akiyama H‚ Maeda Y‚ Usui N‚ Saburi Y‚ Ishida T‚ Kosugi H‚ Miyamura K‚ Miyazaki Y‚ Handa H‚ Yokota A‚ Matsumoto K‚ Fujimaki K‚ Matsui T‚ Kiyoi H‚ Miyawaki S‚ Ohtake S‚ Ohno R‚ Naoe T   Excellent long-term outcomes of imatinib therapy in newly diagnosed Japanese patients with chronic myelogenous leukemia in chronic phase: Analysis of the mean daily doses and blood levels of imatinib in the JALSG CML202 study
Cancer Sci  2012;  103   (6):   1071-1078


Usuki K‚ Tojo A‚ Maeda Y‚ Kobayashi Y‚ Matsuda A‚ Ohyashiki K‚ Nakaseko C‚ Kawaguchi T‚ Tanaka H‚ Miyamura K‚ Miyazaki Y‚ Okamoto S‚ Oritani K‚ Okada M‚ Usui N‚ Nagai T‚ Amagasaki T‚ Wanajo A‚ Naoe T   Efficacy and safety of nilotinib in Japanese patients with imatinib-resistant or -intolerant Ph+ CML or relapsed/refractory Ph+ ALL: a 36-month analysis of a phase I and II study
Int J Hematol  2012;  95   (4):   409-419


Tsukamoto S‚ Takeuchi M‚ Kawajiri C‚ Tanaka S‚ Nagao Y‚ Sugita Y‚ Yamazaki A‚ Kawaguchi T‚ Muto T‚ Sakai S‚ Takeda Y‚ Ohwada C‚ Sakaida E‚ Shimizu N‚ Yokote K‚ Iseki T‚ Nakaseko C   Posterior reversible encephalopathy syndrome in an adult patient with acute lymphoblastic leukemia after remission induction chemotherapy.
Int J Hematol  2012;  95   (2):   204-208


Yokota A‚ Ozawa S‚ Tsuji M‚ Akiyama H‚ Ohshima K‚ Kanda Y‚ Takahashi S‚ Mori T‚ Nakaseko C‚ Onoda M‚ Kishi K‚ Doki N‚ Aotsuka N‚ Kanamori H‚ MarutaA‚ Sakamaki H‚ Okamoto S   Secondary solid tumors aftger allogeeic stem cell transplantation in Japan
Bone Marrow Transplant  2012;  47   (1):   95-100


Koshizaka M‚ Takemoto M‚ Sato S‚ Tokuyama H‚ Fujimoto M‚ Okabe E‚ Ishibashi R‚ Ishikawa T‚ Tsurutani Y‚ Onishi S‚ Mezawa M‚ He P‚ Honjo S‚ Ueda S‚ Saito Y‚ Yokote K   An Angiotensin II Type 1 Receptor Blocker Prevents Renal Injury via Inhibition of the Notch Pathway in Ins2 Akita Diabetic Mice
Experimental Diabetes Research  2012;  in press    


Tanaka H‚ Ohwada C‚ Hashimoto S‚ Sakai S‚ Takeda Y‚ Abe D‚ Takagi T‚ Ohshima K‚ Nakaseko C.   Leukemic presentation of ALK-negative anaplastic large cell lymphoma in a patient with myelodysplastic syndrome.
Intern Med  2012;  51   (2):   199-203


Shimizu N‚ Nakaseko C‚ Sakaida E‚ Ohwada C‚ Takeuchi M‚ Tanaka S‚ Muto T‚ Kawaguchi T‚ Tsukamoto S‚ Sakai S‚ Takeda Y‚ Abe D‚ Yokote K‚ Iseki T‚ Kanai K‚ Misawa S‚ Kuwabara S.   Factors associated with the efficiency of peripheral blood stem cell harvest in patients with POEMS syndrome undergoing autologous peripheral blood stem cell transplantation.
Bone Marrow Transplant  2012;     


Sazuka S‚ Takahashi Y‚ Sato T‚ Nakagawa T‚ Furuya Y‚ Saito M‚ Saito K‚ Kawaguchi T‚ Nakaseko C‚ Katsuno T‚ Yokosuka O.   Endoscopic findings of small intestinal EBV-associated T-cell lymphoproliferative disorder.
Endoscopy  2012;      E30-E31


¢¥PageTop

Books

Takemoto M‚ Mori S‚ Kuzuya M‚ Yoshimoto S‚Shimamoto A ‚ Igarashi M‚ Tanaka Y‚ Miki T‚ Yokote Y   Diagnostic criteria for Werner syndrome based on Japanese nationwide epidemiological survay.   Geriatr Gerontol Int  2012;   in press    


¢¥PageTop

International Conferences

Yoshida‚ T. Effective treatment of hypothyroidism with powdered medicine and its involvement of efflux transporter BCRP in a patient with multidrug resistance 
ENDO2012 2012-6-24 Houston/USA


Yokote‚ K. Mission of medical research in aging society 
ÀéÍÕÂç³Ø¤È¹âͺ°å³ØÂç³Ø»ÐËå¹»¶¨ÄêÄù·ëµ­Ç°¹Ô»ö 2012-5-5 Kaohsiung/Taiwan


Yokote‚ K. Cellular regulation in diabetic complications 
2012 Shanghai Symposium on Obesity and Diabetes 2012-4-7 Shanghai/China


Yokote‚ K.. Lipid management guideline in Japan 
XVI International Symposium on Atherosclerosis 2012-3-26 Sydney/Australia


Okabe‚ E Incidence and characteristics of metabolic disorders and vascular complications in Werner syndrome patients in Japan 
International Conference on Orphan Drugs and Rare Diseases 2012-2-5 Tokyo/Japan


Ishibashi‚ R . Semaphorin3g regulates endothelial cell fenestration and the structure of podocyte foot processes 
48th EASD Annual Meeting 2012-10-5 Berlin/Germany


Motegi‚ H . 1‚5-anhydroglucitol is useful for an assessment of glycemic excursion and short-term improvement of glycemic control correlating with an evaluation by continuous glucose monitoring system 
8th Asian-Pacific Society of Atherosclerosis and Vascular Disease 2012-10-20 Phuket/Thailand


Yokote‚ K . Lipid management guideline in A-P region. 
8th Asian-Pacific Society of Atherosclerosis and Vascular Disease 2012-10-20 Phuket/Thailand


Yokote‚ K . Familial hypercholesterolemia‚ model of care in Asian-Pacific region. 
8th Asian-Pacific Society of Atherosclerosis and Vascular Disease 2012-10-20 Phuket/Thailand


Motegi‚ H. 1‚5-anhydroglucitol is useful for an assessment of glycemic excursion and short-term improvement of glycemic control correlating with an evaluation by continuous glucose monitoring system 
8th Asian-Pacific Society of Atherosclerosis and Vascular Disease 2012-10-20 Phuket/Bangkok


Ishikawa‚ T . Investigation of the podocyte-secreted protein R3h domain containing-like in diabetic nephropathy 
48th EASD Annual Meeting 2012-10-1 Berlin/Germany


Ishibashi‚ R . Semaphorin3g regulates endothelial cell fenestration and the structure of podocyte foot processes 
48th EASD Annual Meeting 2012-10-1 Berlin/Germany


Ishikawa‚ T . Investigation of the podocyte-secreted protein R3h domain containing-like in diabetic nephropathy 
48th EASD Annual Meeting 2012-10-1 Berlin/Germany


¢¥PageTop