Research Achievements
Osamu Ohara| 2012 | 2011 | 2010 | 2009 | 2008 |
	
		| Papers| International Conferences |
Papers
Endoh M‚ Endo TA‚ Endoh T‚ Isono K‚ Sharif J‚ Ohara O‚ Toyoda T‚ Ito T‚ Eskeland R‚ Bickmore WA‚ Vidal M‚ Bernstein BE‚ Koseki H.   Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity.
				PLoS Genet.  2012;   8   (7):   e1002774-  
Hori T‚ Ohnishi H‚ Teramoto T‚ Tsubouchi K‚ Naiki T‚ Hirose Y‚ Ohara O‚ Seishima M‚ Kaneko H‚ Fukao T‚ Kondo N.   Autosomal-Dominant Chronic Mucocutaneous Candidiasis with STAT1-Mutation can be Complicated with Chronic Active Hepatitis and Hypothyroidism.
				J Clin Immunol  2012;   in press        
Kaji T‚ Ishige A‚ Hikida M‚ Taka J‚ Hijikata A‚ Kubo M‚ Nagashima T‚ Takahashi Y‚ Kurosaki T‚ Okada M‚ Ohara O‚ Rajewsky K‚ Takemori T.   Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.
				J Exp Med.  2012;   in press        
Nakaoka H‚ Kanegane H‚ Taneichi H‚ Miya K‚ Yang X‚ Nomura K‚ Takezaki S‚ Yamada M‚ Ohara O‚ Kamae C‚ Imai K‚ Nonoyama S‚ Wada T‚ Yachie A‚ Hershfield MS‚ Ariga T‚ Miyawaki T.   Delayed onset adenosine deaminase deficiency associated with acute disseminated encephalomyelitis.
				Int J Hematol.  2012;   95   (6):   692-696  
Mohammadzadeh I‚ Yeganeh M‚ Aghamohammadi A‚ Parvaneh N‚ Behniafard N‚ Abolhassani H‚ Tabassomi F‚ Hemmat M‚ Kanegane H‚ Miyawaki T‚ Ohara O‚ Rezaei N.   Severe primary antibody deficiency due to a novel mutation of micro heavy chain.
				J Investig Allergol Clin Immunol.  2012;   22   (1):   78-79  
Tofukuji S‚ Kuwahara M‚ Suzuki J‚ Ohara O‚ Nakayama T‚ Yamashita M.   Identification of a New Pathway for Th1 Cell Development Induced by Cooperative Stimulation with IL-4 and TGF-¦Ā.
				Immunol.  2012;   188   (10):   4846-4857  
Suri D‚ Singh S‚ Rawat A‚ Gupta A‚ Kamae C‚ Honma K‚ Nakagawa N‚ Imai K‚ Nonoyama S‚ Oshima K‚ Mitsuiki N‚ Ohara O‚ Bilhou-Nabera C‚ Proust A‚ Ahluwalia J‚ Dogra S‚ Saikia B‚ Minz RW‚ Sehgal S.   Clinical profile and genetic basis of Wiskott-Aldrich syndrome at Chandigarh‚ North India.
				Asian Pac J Allergy Immunol.  2012;   30   (1):   71-78  
Takezaki S‚ Yamada M‚ Kato M‚ Park MJ‚ Maruyama K‚ Yamazaki Y‚ Chida N‚ Ohara O‚ Kobayashi I‚ Ariga T.   Chronic Mucocutaneous Candidiasis Caused by a Gain-of-Function Mutation in the STAT1 DNA-Binding Domain.
				J Immunol.  2012;   In press        
Fukaya T‚ Murakami R‚ Takagi H‚ Sato K‚ Sato Y‚ Otsuka H‚ Ohno M‚ Hijikata A‚ Ohara O‚ Hikida M‚ Malissen B‚ Sato K.   Conditional ablation of CD205+ conventional dendritic cells impacts the regulation of T-cell immunity and homeostasis in vivo.
				Proc Natl Acad Sci U S A.  2012;   In press        
Mizuno T‚ Sakai H‚ Nishikomori R‚ Oshima K‚ Ohara O‚ Hata I‚ Shigematsu Y‚ Ishige T‚ Tamura K‚ Arakawa H.   Novel mutations of MVK gene in Japanese family members affected with hyperimmunoglobulinemia D and periodic fever syndrome.
				Rheumatol Int.  2012;   in press        
Takagi S‚ Saito Y‚ Hijikata A‚ Tanaka S‚ Watanabe T‚ Hasegawa T‚ Mochizuki S‚ Kunisawa J‚ Kiyono H‚ Koseki H‚ Ohara O‚ Saito T‚ Taniguchi S‚ Shultz LD‚ Ishikawa F.   Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation.
				Blood.  2012;   119   (12):   2768-2777  
Izawa K‚ Hijikata A‚ Tanaka N‚ Kawai T‚ Saito MK‚ Goldbach-Mansky R‚ Aksentijevich I‚ Yasumi T‚ Nakahata T‚ Heike T‚ Nishikomori R‚ Ohara O.   Detection of Base Substitution-Type Somatic Mosaicism of the NLRP3 Gene with >99.9% Statistical Confidence by Massively Parallel Sequencing.
				DNA Res.  2012;   19   (2):   143-152  
International Conferences
Osamu Ohara Integra1ve Medical Sciences at RIKEN RCAI: to understand the process of disease development 
				Australia-Japan workshop on biomedical breakthroughs and systems biology 2012-10-16 Tokyo/Japan

