Research Achievements

Osamu Ohara

2012 | 2011 | 2010 | 2009 | 2008 |
| Papers| International Conferences |

Papers

Endoh M‚ Endo TA‚ Endoh T‚ Isono K‚ Sharif J‚ Ohara O‚ Toyoda T‚ Ito T‚ Eskeland R‚ Bickmore WA‚ Vidal M‚ Bernstein BE‚ Koseki H.   Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity.
PLoS Genet.  2012;  8   (7):   e1002774-


Hori T‚ Ohnishi H‚ Teramoto T‚ Tsubouchi K‚ Naiki T‚ Hirose Y‚ Ohara O‚ Seishima M‚ Kaneko H‚ Fukao T‚ Kondo N.   Autosomal-Dominant Chronic Mucocutaneous Candidiasis with STAT1-Mutation can be Complicated with Chronic Active Hepatitis and Hypothyroidism.
J Clin Immunol  2012;  in press    


Kaji T‚ Ishige A‚ Hikida M‚ Taka J‚ Hijikata A‚ Kubo M‚ Nagashima T‚ Takahashi Y‚ Kurosaki T‚ Okada M‚ Ohara O‚ Rajewsky K‚ Takemori T.   Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.
J Exp Med.  2012;  in press    


Nakaoka H‚ Kanegane H‚ Taneichi H‚ Miya K‚ Yang X‚ Nomura K‚ Takezaki S‚ Yamada M‚ Ohara O‚ Kamae C‚ Imai K‚ Nonoyama S‚ Wada T‚ Yachie A‚ Hershfield MS‚ Ariga T‚ Miyawaki T.   Delayed onset adenosine deaminase deficiency associated with acute disseminated encephalomyelitis.
Int J Hematol.  2012;  95   (6):   692-696


Mohammadzadeh I‚ Yeganeh M‚ Aghamohammadi A‚ Parvaneh N‚ Behniafard N‚ Abolhassani H‚ Tabassomi F‚ Hemmat M‚ Kanegane H‚ Miyawaki T‚ Ohara O‚ Rezaei N.   Severe primary antibody deficiency due to a novel mutation of micro heavy chain.
J Investig Allergol Clin Immunol.  2012;  22   (1):   78-79


Tofukuji S‚ Kuwahara M‚ Suzuki J‚ Ohara O‚ Nakayama T‚ Yamashita M.   Identification of a New Pathway for Th1 Cell Development Induced by Cooperative Stimulation with IL-4 and TGF-¦Ā.
Immunol.  2012;  188   (10):   4846-4857


Suri D‚ Singh S‚ Rawat A‚ Gupta A‚ Kamae C‚ Honma K‚ Nakagawa N‚ Imai K‚ Nonoyama S‚ Oshima K‚ Mitsuiki N‚ Ohara O‚ Bilhou-Nabera C‚ Proust A‚ Ahluwalia J‚ Dogra S‚ Saikia B‚ Minz RW‚ Sehgal S.   Clinical profile and genetic basis of Wiskott-Aldrich syndrome at Chandigarh‚ North India.
Asian Pac J Allergy Immunol.  2012;  30   (1):   71-78


Takezaki S‚ Yamada M‚ Kato M‚ Park MJ‚ Maruyama K‚ Yamazaki Y‚ Chida N‚ Ohara O‚ Kobayashi I‚ Ariga T.   Chronic Mucocutaneous Candidiasis Caused by a Gain-of-Function Mutation in the STAT1 DNA-Binding Domain.
J Immunol.  2012;  In press    


Fukaya T‚ Murakami R‚ Takagi H‚ Sato K‚ Sato Y‚ Otsuka H‚ Ohno M‚ Hijikata A‚ Ohara O‚ Hikida M‚ Malissen B‚ Sato K.   Conditional ablation of CD205+ conventional dendritic cells impacts the regulation of T-cell immunity and homeostasis in vivo.
Proc Natl Acad Sci U S A.  2012;  In press    


Mizuno T‚ Sakai H‚ Nishikomori R‚ Oshima K‚ Ohara O‚ Hata I‚ Shigematsu Y‚ Ishige T‚ Tamura K‚ Arakawa H.   Novel mutations of MVK gene in Japanese family members affected with hyperimmunoglobulinemia D and periodic fever syndrome.
Rheumatol Int.  2012;  in press    


Takagi S‚ Saito Y‚ Hijikata A‚ Tanaka S‚ Watanabe T‚ Hasegawa T‚ Mochizuki S‚ Kunisawa J‚ Kiyono H‚ Koseki H‚ Ohara O‚ Saito T‚ Taniguchi S‚ Shultz LD‚ Ishikawa F.   Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation.
Blood.  2012;  119   (12):   2768-2777


Izawa K‚ Hijikata A‚ Tanaka N‚ Kawai T‚ Saito MK‚ Goldbach-Mansky R‚ Aksentijevich I‚ Yasumi T‚ Nakahata T‚ Heike T‚ Nishikomori R‚ Ohara O.   Detection of Base Substitution-Type Somatic Mosaicism of the NLRP3 Gene with >99.9% Statistical Confidence by Massively Parallel Sequencing.
DNA Res.  2012;  19   (2):   143-152


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International Conferences

Osamu Ohara Integra1ve Medical Sciences at RIKEN RCAI: to understand the process of disease development 
Australia-Japan workshop on biomedical breakthroughs and systems biology 2012-10-16 Tokyo/Japan


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