Research Achievements
Toshinori Nakayama| 2012 | 2011 | 2010 | 2009 | 2008 |
	
		| Papers| International Conferences |
Papers
Fujii‚ S.‚ Motohashi‚ S.‚ Shimizu‚ K.‚ Nakayama‚ T.‚ Yoshiga‚ Y.‚ and Taniguchi‚ M.   Adjuvant activity mediated by iNKT cells.
				Semin. Immunol.  2010;   22      97-102  
Ishii‚ Y.‚ Motohashi‚ S.‚ Shimizu‚ K.‚ Nakayama‚ T.‚ Taniguchi‚ M.‚ and Fujii‚ S.   Application of NKT cells in immunotherapy.
				Curr. Immunol. Rev.  2010;   6      109-115  
Nakayama‚ T.‚ and Yamashita‚ M.   The TCR-mediated signaling pathways that control the direction of helper T cell differentiation.
				Semin.Immunol.  2010;   22   (5):   303-309  
Nakayama‚ T.‚ and Kimura‚ M. Y.   Memory Th1/Th2 cell generation controlled Schnurri-2.
				Adv.Exp.Med.Biol  2010;   684      1-10  
Iwamura‚ C.‚ and Nakayama‚ T.   Role of NKT cells in allergic asthma.
				Curr.Opin.Immunol.  2010;   22   (6):   807-813  
Onodera‚ A.‚ Yamashita‚ M.‚ Endo‚ Y.‚ Kuwahara‚ M.‚ Tofukuji‚ S.‚ Hosokawa‚ H.‚ Kanai‚ A.‚ Suzuki‚ Y.‚ and Nakayama‚ T.   STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells.
				J.Exp.Med  2010;   207      2493-2506  
Okita‚ K.‚ Motohashi‚ S.‚ Shinnakasu‚ R.‚ Nagato‚ K.‚ Yamasaki‚ K.‚ Sato‚ Y.‚ Kitamura‚ H.‚ Hijikata‚ A.‚ Yamashita‚ M.‚ Shimizu‚ K.‚ Fujii‚ S.‚ Ohara‚ O.‚ Taniguchi‚ M.‚ Sakaida‚ I.‚ and Nakayama‚ T.   A set of genes associated with the interferon-¦Ã response of lung cancer patients undergoing ¦Á-galactosylceramide-pulsed dendritic cell therapy.
				Cancer Sci.  2010;   101      2333-2340  
Igari‚ H.‚ Segawa‚ S.‚ Watanabe‚ A.‚ Suzuki‚ A.‚ Watanabe‚ M.‚ Sakurai‚ T.‚ Kuroda‚ F.‚ Watanabe‚ M.‚ Tatsumi‚ K.‚ Nakayama‚ M.‚ Nakayama‚ T.‚ Suzuki‚ K.‚ and Sato‚ T.   Immunogenicity of a monovalent pandemic influenza AH1N1 vaccine in health-care workers of a university hospital in Japan.
				Microbiol.Immunol.  2010;   5      618-624  
Kobayashi‚ K.‚ Tanaka‚ Y.‚ Horiguchi‚ S.‚ Yamamoto‚ S.‚ Nakayama‚ T.‚ Sugimoto‚ A.‚ and Okamoto‚ Y.   The effect of radiotherapy on NKT cells in patients with advanced head and neck cancer.
				Cancer Immunol. Immunother  2010;   59      1503-1509  
Ichiyanagi‚ T.‚ Imai‚ T.‚ Kajiwara‚ C.‚ Mizukami‚ S.‚ Nakai‚ A.‚ Nakayama‚ T.‚ and Udono‚ H.   Essential role of endogenous heat shock protein 90 of dendritic cells in antigen cross-presentation.
				J.Immunol.  2010;   185      2693-2700  
Ishio N‚ Kobayashi Y‚ Iwata Y‚ Kitahara H‚ Fukushima K‚ Asano T‚ Nakayama T‚ Kuroda N‚ Komuro I.   Ubiquitous atherosclerosis in coronary arteries without angiographically significant stenosis.
				Heart Vessels  2010;   25   (1):   35-40  
Suzuki A.‚ Iwamura C.‚ Shinoda K.‚ Tumes J. D.‚ Kimura Y. M.‚ Hosokawa H.‚ Endo Y.‚ Horiuchi S.‚ Tokoyoda K.‚ Koseki H.‚ Yamashita M.‚ and Nakayama T.   Polycomb group gene product Ring1B regulates Th2-driven airway inflammation through the inhibition of Bim-mediated apoptosis of effector Th2 cells in the lung.
				J. Immunol.  2010;   184   (8):   4510-4520  
Fujimura T.‚ Yonekura S.‚ Taniguchi Y.‚ Horiguchi S.‚ Saito A.‚ Yasueda H.‚ Nakayama T.‚ Takemori T.‚ Taniguchi M.‚ Sakaguchi M.‚ and Okamoto Y.   The induced regulatory T-cell level‚ defined as the proportion of IL10+Foxp3+ cells among CD25+CD4+ leukocytes‚ is an available therapeutic biomarker for sublingual immunotherapy: A preliminary report.
				Int. Arch. Allergy Immunol.  2010;   153   (4):   378-387  
Suzuki S.‚ Tanaka T.‚ Poyurovsky V. M.‚ Nagano H.‚ Mayama T.‚ Ohkubo S.‚ Lokshin M.‚ Hosokawa H.‚ Nakayama T.‚ Suzuki Y.‚ Sugano S.‚ Sato E.‚ Nagao T.‚ Yokote K.‚ Tatsuno I.‚ and Prives C.   Phosphate activated glutaminase (GLS2)‚ a p53-inducible regulator of glutamine metabolism and reactive oxygen species.
				Proc. Natl. Acad. Sci. USA  2010;   107   (16):   7461-7466  
Tokoyoda K.‚ Hauser A. E.‚ Nakayama T.‚ and Radbruch A.   Organization of immunological memory by bone marrow stroma.
				Nat. Rev. Immunol.  2010;   10      193-200  
Tomizawa‚ K.‚ Nagao‚ T.‚ Kusunoki‚ R.‚ Saiga‚ K.‚ Oshima‚ M.‚ Kobayashi‚ K.‚ Nakayama‚ T.‚ Tanokura‚ M.‚ and Suzuki‚ K.   Reduction of MPO-ANCA epitopes in SCG/Kj mice by 15-Deoxyspergualin treatment restricted by IgG2b associated with crescentic glomerulonephritis.
				Rheumatology  2010;   49   (7):   1245-1256  
Iwata‚ A.‚ Watanabe‚ N.‚ Oya‚ Y.‚ Owada‚ T.‚ Ikeda‚ K.‚ Suto‚ A.‚ Kagami‚ S.‚ Hirose‚ K.‚ Kanari‚ H.‚ Kawashima‚ S.‚ Nakayama‚ T.‚ Taniguchi‚ M.‚ Iwamoto‚ I.‚ and Nakajima‚ H.   Protective roles of B and T lymphocyte attenuator in NKT cell-mediated experimental hepatitis.
				J. Immunol.  2010;   184   (1):   127-133  
Iwamura‚ C.‚ Shinoda‚ K.‚ Yoshimura‚ M.‚ Watanabe‚ Y.‚ Obata‚ A.‚ and Nakayama‚ T.   Naringenin chalcone suppresses allergic asthma by inhibiting the type-2 function of CD4 T cells.
				Allergology International  2010;   59   (1):   67-73  
Nakayama T.‚ Kimura Y.M.   Memory Th1/Th2 cell generation controlled by schnurri-2.
				Memory T-Cells  2010;   684      1-10  
Hasegawa A‚ Hayashi K‚ Kishimoto H‚ Yang M‚ Tofukuji S‚ Suzuki K‚ Nakajima H‚ Hoffman R‚ Shirai M‚ Nakayama T.   Color-coded real-time cellular imaging of T lymphocyte accumulation and focus formation in mouse asthma model.
				J Allergy Clin. Immunol.  2010;   125      461-468  
International Conferences
Nakayama‚ T CD4 T cell memory controlled by Polycomb and Trithorax molecules. 
				The 10th Awaji International Forum on Infection and Immunity 2010-9-7 Awaji/Japan
Taniguchi‚ M.‚ Fujii‚ S.‚ Motohashi‚ S.‚ and Nakayama‚ T. NKT cell-targeted adjuvant cell therapy-from basic to clinic. 
				14th International Congress of Immunology 2010-8-22 Kobe/Japan
Nakayama‚ T. iNKT cell-based immunotherapy for cancer. 
				Corporate Thursday Clinical Immunology Society 2010-5-20 Philadelphia/USA
Sugamata R‚ Nagao T‚ Dobashi H‚ Tomizawa K. Yamamoto K‚ Nakajima N‚ Sato Y‚ Aratani Y‚ Todaka R‚ Oshima M‚ Sata T‚ Kobayashi K‚ Kawachi S‚  Nakayama T‚ Suzuki K. Role of neutrophils and myeloperoxidase in lung injury induced by influenza A/H1N1 (PR-8) infection in mice. 
				Annual scientific meeting of the European Society for Clinical Investigation 2010-2-24 Bari/Italy
Hasegawa‚ A.‚ and Nakayama‚ T. Real-time cellular imaging of T lymphocyte migration in a mouse asthma model. 
				3rd International Bioimaging Symposium 2010-1-18 Okazaki/Japan
Nagao T‚ Aratani Y‚ Nakayama T‚ Suzuki K Development of murine crescentic glomerulonephritis model using anti-MPO and anti-LAMP-2 antibodies 
				Inflammation Program 2010-1-15 Chiba/Japan
Nakayama‚ T. Dual negative regulation of GATA3 function by Sox4. Adaptive and Innate Immune Responses to Neglected Tropical Diseases Conference 
				US-JAPAN Joint Immunology Board&Parastic Disease Panel Conference 2010-1-10 San Diego/USA

