Research Achievements
Toshinori Nakayama| 2012 | 2011 | 2010 | 2009 | 2008 |
| Papers| International Conferences |
Papers
Iwamura C‚ Shinoda K‚ Endo Y‚ Watanabe Y‚ Tumes D.J‚ Motohashi S‚ Kawahara K‚ Kinjo Y‚ Nakayama T. Regulation od memory CD4 T-cell pool size and function by natural killer T cells in vivo.
Proceedings of the National Academy of Sciences of the United States of America. 2012; 109 (42): 16992-16997
Lavial‚ F.‚ Bessonnard‚ S.‚ Ohnishi‚ Y.‚ Tsumura‚ A.‚ Chandrashekran‚ A.‚ Fenwick‚ M.‚ Tomaz‚ R. A.‚ Hosokawa‚ H.‚ Nakayama‚ T.‚ Chambers‚ I.‚ Hiiragi‚ T.‚ Chazaud‚ C.‚ and Azuara‚ V. Bmi1 facilitates primitive endoderm formation by stabilizing Gata6 during early mouse development.
Genes Dev. 2012; In press
Nagato‚ K.‚ Motohashi‚ S.‚ Ishibashi‚ F.‚ Okita‚ K.‚ Yamasaki‚ K.‚ Moriya‚ Y.‚ Hoshino‚ H.‚ Yoshida‚ S.‚ Hanaoka‚ H.‚ Fuji‚ S.‚ Taniguchi‚ M.‚ Yoshino‚ I.‚ and Nakayama‚ T. Accumulation of activated invariant natural killer T cells in the tumor microenvironment after ¦Á-Galactosylceramide-pulsed antigen presenting cells.
J. Clin. Immunol. 2012; In press
Watanabe‚ M.‚ Nakajima‚ S.‚ Ohnuki‚ K.‚ Ogawa‚ S.‚ Yamashita‚ M.‚ Nakayama‚ T.‚ Murakami‚ Y.‚ Tanabe‚ K.‚ and Abe‚ R. The transcription factor AP-1 is involved in ICOS gene expression downstream of TCR/CD28 signaling and cytokine receptor signaling.
Eur. J. Immunol. 2012; In press
Radulovic‚ K.‚ Manta‚ C.‚ Rossini‚ V.‚ Holzmann‚ K.‚ Kestler‚ H. A.‚ Wegenka‚ U. M.‚ Nakayama‚ T.‚ and Niess‚ J. H. CD69 regulates type I IFN-induced tolerogenic signals to mucosal CD4 T cells that attenuate their colitogenic potential.
J Immunol. 2012; 188 (4): 2001-2013
Shinoda‚ K.‚ Tokoyoda‚ K.‚ Hanazawa‚ A.‚ Hayashizaki‚ K.‚ Zehentmeier‚ S.‚ Hosokawa‚ H.‚ Iwamura‚ C.‚ Koseki‚ H.‚ Tumes‚ J. D.‚ Radbruch‚ A.‚ and Nakayama‚ T. Type II membrane protein CD69 regulates the formation of resting T-helper memory.
Proc Natl Acad Sci U S A. 2012; 109 (19): 7409-7414
Ishizaki‚ S.‚ Kasuya‚ Y.‚ Kuroda‚ F.‚ Tanaka‚ K.‚ Tsuyusaki‚ J.‚ Yamauchi‚ K.‚ Matsunaga‚ H.‚ Iwamura‚ C.‚ Nakayama‚ T.‚ and Tatsumi‚ K. Role of CD69 in acute lung injury.
Life Sciences 2012; 90 (17-18): 657-665
Inamine‚ A.‚ Sakurai‚ D.‚ Horiguchi‚ S.‚ Yonekura‚ S.‚ Hanazawa‚ T.‚ Hosokawa‚ H.‚ Matuura-Suzuki‚ A.‚ Nakayama‚ T.‚ and Okamoto‚ Y. Sublingual administration of Lactobacillus paracasei KW3110 inhibits Th2-dependent allergic responses via upregulation of PD-L2 on dendritic cells.
Clin.Immunol. 2012; 143 (2): 170-179
Miyasaka‚ T.‚ Aoyagi‚ T.‚ Uchiyama‚ B.‚ Oishi‚ K.‚ Nakayama‚ T.‚ Kinjo‚ Y.‚ Miyazaki‚ Y.‚ Kunishima‚ H.‚ Hirakata‚ Y.‚ Kaku‚ M.‚ and Kawakami‚ K. A possible relationship of natural killer T cells with humoral immune response to 23-valent pneumococcal polysaccharide vaccine in clinical settings
Vaccine 2012; 39 (22): 3304-3310
Kuwahara‚ M.‚ Yamashita‚ M.‚ Shinoda‚ K.‚ Tofukuji‚ S.‚ Onodera‚ A.‚ Shinnakasu‚ R.‚ Motohashi‚ S.‚ Hosokawa‚ H.‚ Tumes‚ D.‚ Iwamura‚ C.‚ Lefebvre‚ V.‚ and Nakayama‚ T.: The transcription factor Sox4 is a downstream target of TGF-¦Â signaling and suppresses GATA3-induced TH2 cell differentiation.
Nat. Immunol. 2012; 13 (8): 778-786
Yamashita‚ J.‚ Iwamura‚ C.‚ Mitsumori‚ K.‚ Hosokawa‚ H.‚ Sasaki‚ T.‚ Takahashi‚ M.‚ Tanaka‚ H.‚ Kaneko‚ K.‚ Hanazawa‚ A.‚ Watanabe‚ Y.‚ Shinoda‚ K.‚ Tumes‚ D.‚ Motohashi‚ S.‚ Nakayama‚ T. Murine Schnurri-2 controls Natural Killer cell function and lymphoma development.
Leuk. Lymphoma 2012; 53 (3): 479-486
Satoh‚ M.‚ Andoh‚ Y.‚ Clingan‚ S. C.‚ Ogura‚ H.‚ Fujii‚ S.‚ Nakayama‚ T.‚ Taniguchi‚ M.‚ Hirata‚ N.‚ Ishimori‚ N.‚ Tsutsui‚ H.‚ Onoe‚ K.‚ and Iwabuchi‚ K. Type II NKT cells stimulate diet-induced obesity by mediating adipose tissue inflammation‚ steatohepatitis and insulin resistance.
PLoS ONE 2012; 7 (2): e30568-
Kidoya‚ H.‚ Kunii‚ N.‚ Naito‚ H.‚ Muramatsu‚ T.‚ Okamoto‚ Y.‚ Nakayama‚ T.‚ and Takakura‚ N. The apelin/APJ system induces maturation of the tumor vasculature and improves the efficiency of immune therapy.
Oncogene 2012; in press
Aoyagi‚ Y.‚ Kuroda‚ M.‚ Asada‚ S.‚ Tanaka‚ S.‚ Konno‚ S‚. Tanio‚ M.‚ Aso‚ M.‚ Okamoto‚ Y.‚ Nakayama‚ T.‚ Saito‚ Y.‚ Bujo‚ H. Fibrin glue is a candidate scaffold for long-term therapeutic protein expression in spontaneously differentiated adipocytes in vitro.
Exp Cell Res. 2012; 318 (1): 8-15
International Conferences
Endo. Y.‚ Nakayama.T. Identification of pathogenic memory Th2 cells that produce IL-5 and regulate allergic airway inflammation.
European Academy of Allergy and Clinical Immunology Congress 2012 2012-6-16 Geneva/Switzerland
Nagato‚ K.‚Motohashi‚ S. Nakayama‚T. Accumulation of activated invariant NKT cells in the tumor microenvironment after ¦Á-galactosylceramide-pulsed antigen presenting cells.
Clinical Immunology Society (CIS) Annual Meeting 2012-5-17 Chicago/USA
Nakayama‚ T. Pathogenic memory Th2 cells in airway inflammation.
novo nordisk innovation summit Tokyo 2012 chronic inflammation and autoimmune diseases 2012-4-17 Tokyo/Japan
Shinoda K. CD69 regulates the formation of resting T helper memory
14th International Conference on Lymphocyte Activation and Immune Regulation 2012-3-3 NewPort Beach/USA
Endo Y. Eomesodermin controls IL-5 production in memory Th2 cells through the inhibition of GATA3 activity
14th International Conference on Lymphocyte Activation and Immune Regulation 2012-2-3 Newport Beach/USA
