Research Achievements
Issei Komuro| 2012 | 2011 | 2010 | 2009 | 2008 |
| Papers| International Conferences |
Papers
Odaka K‚ Aoki I‚ Moriya J‚ Tateno K‚ Tadokoro H‚ Kershaw J‚ Minamino T‚ Irie T‚ Fukumura T‚ Komuro I‚ Saga T. In vivo tracking of transplanted mononuclear cells using manganese-enhanced magnetic resonance imaging (MEMRI).
PLoS One. 2011; 6e25487
Kobayashi N‚ Odaka K‚ Uehara T‚ Imanaka-Yoshida K‚ Kato Y‚ Oyama H‚ Tadokoro H‚ Akizawa H‚ Tanada S‚ Hiroe M‚ Fukumura T‚ Komuro I‚ Arano Y‚ Yoshida T‚ Irie T. Toward in vivo imaging of heart disease using a radiolabeled single-chain Fv fragment targeting tenascin-C.
Anal Chem 2011; 83 9123-9130
Yuasa-Kawase M‚ Masuda D‚ Yamashita T‚ Kawase R‚ Nakaoka H‚ Inagaki M‚ Nakatani K‚ Tsubakio-Yamamoto K‚ Ohama T‚ Matsuyama A‚ Nishida M‚ Ishigami M‚ Kawamoto T‚ Komuro I‚ Yamashita S. Patients with CD36 Deficiency Are Associated with Enhanced Atherosclerotic Cardiovascular Diseases.
J Atheroscler Thromb 2011;
Sasaki K‚ Yoshida A‚ Nakata Y‚ Mizote I‚ Sakata Y‚ Komuro I. A case of thyroid storm with multiple organ failure effectively treated with plasma exchange.
Intern Med 2011; 50 2801-2805
Hara M‚ Mizuno H‚ Mizote I‚ Nakatani D‚ Asano Y‚ Sakata Y‚ Nanto S‚ Komuro I. Clinical impact of off-label cardiac resynchronization therapy in end-stage heart failure patients on continuous intravenous inotrope.
Clin Cardiol 2011; 34 714-720
Masuda M‚ Inoue K‚ Iwakura K‚ Okamura A‚ Koyama Y‚ Kimura R‚ Toyoshima Y‚ Ito N‚ Komuro I‚ Fujii K. The Impact of Atrial Fibrillation Ablation on Left Atrial Function: Association with Baseline Left Atrial Function.
Pacing Clin Electrophysiol 2011;
Kataoka A‚ Funabashi N‚ Takahashi A‚ Yajima R‚ Takahashi M‚ Uehara M‚ Takaoka H‚ Saito M‚ Yamaguchi C‚ Lee K‚ Nomura F‚ Komuro I. Quantitative evaluation of left atrial volumes and ejection fraction by 320-slice computed-tomography in comparison with three- and two-dimensional echocardiography: A single-center retrospective-study in 22 subjects.
Int J Cardiol 2011; 153 47-54
Kataoka A‚ Funabashi N‚ Yajima R‚ Takahashi M‚ Takahashi A‚ Saito M‚ Yamaguchi C‚ Imaeda T‚ Lee K‚ Komuro I. Differentiation of pseudodyskinesis of inferior left ventricular wall from inferior myocardial infarction by assessment of regional myocardial strain using two-dimensional speckle tracking echocardiography.
Int J Cardiol 2011; 152 362-368
Minamiguchi H‚ Nanto S‚ Onishi T‚ Watanabe T‚ Uematsu M‚ Komuro I. Low atrial septal pacing with dual-chamber pacemakers reduces atrial fibrillation in sick sinus syndrome.
J Cardiol 2011; 57 223-230
Ueda H‚ Yamada T‚ Masuda M‚ Okuyama Y‚ Morita T‚ Furukawa Y‚ Koji T‚ Iwasaki Y‚ Okada T‚ Kawasaki M‚ Kuramoto Y‚ Naito T‚ Fujimoto T‚ Komuro I‚ Fukunami M. Prevention of contrast induced nephropathy by bolus injection of sodium bicarbonate in patients with chronic kidney disease undergoing emergent coronary procedures.
Am J Cardiol 2011; 107 1163-1167
Kurotobi T‚ Iwakura K‚ Inoue K‚ Kimura R‚ Tosyoshima Y‚ Ito N‚ Mizuno H‚ Shimada Y‚ Kinoh N‚ Fujii K‚ Nanto S‚ Komuro I. Electrophysiological features of atrial tachyarrhythmias after the creation of a left atrial roof line during catheter ablation of atrial fibrillation.
Int Heart J 2011; 52 929-927
Takaoka H‚ Ishibashi I‚ Uehara M‚ Rubin GD‚ Komuro I‚ Funabashi N. Comparison of image characteristics of plaques in culprit coronary arteries by 64 slice CT and intravascular ultrasound in acute coronary syndromes.
Int J Cardiol 2011;
Kitahara H‚ Kobayashi Y‚ Iwata Y‚ Fujimoto Y‚ Komuro I. Effect of pioglitazone on endothelial dysfunction after sirolimus-eluting stent implantation.
Am J Cardiol 2011; 108 214-219
Nakatani K‚ Sugimoto T‚ Masuda D‚ Okano R‚ Oya T‚ Monden Y‚ Yamashita T‚ Kawase R‚ Nakaoka H‚ Inagaki M‚ Yuasa-Kawase M‚ Tsubakio-Yamamoto K‚ Ohama T‚ Nishida M‚ Ishigami M‚ Komuro I‚ Yamashita S. Serum apolipoprotein B-48 levels are correlated with carotid intima-media thickness in subjects with normal serum triglyceride levels.
Atherosclerosis 2011; 218 226-232
Nomura S‚ Funabashi N‚ Sekiguchi Y‚ Masuda S‚ Kuwabara S‚ Misawa S‚ Daimon M‚ Uehara M‚ Miyaiuchi H‚ Komuro I‚ Kobayashi Y. Dilated cardiomyopathy with centronuclear myopathy in a young male.
Int J Cardiol 2011; 150 213-216
Takeda Y‚ Sakata Y‚ Mano T‚ Ohtani T‚ Tamaki S‚ Omori Y‚ Tsukamoto Y‚ Aizawa Y‚ Komuro I‚ Yamamoto K. Diabetic retinopathy is associated with impaired left ventricular relaxation.
J Card Fail 2011; 17 556-560
Muratsu J‚ Hara M‚ Mizote I‚ Asano Y‚ Sakata Y‚ Saito S‚ Matsumiya G‚ Sawa Y‚ Komuro I. The impact of cardiac resynchronization therapy in an end-stage heart failure patient with a left ventricular assist device as a bridge to recovery. A case report.
Int Heart J 2011; 52 246-247
Kurotobi T‚ Shimada Y‚ Kino N‚ Iwakura K‚ Inoue K‚ Kimura R‚ Tosyoshima Y‚ Mizuno H‚ Okuyama Y‚ Fujii K‚ Nanto S‚ Komuro I. Local Coronary Flow is Associated with an Unsuccessful Complete Block line at the Mitral Isthmus in Patients with Atrial Fibrillation.
Circ Arrhythm Electrophysiol. 2011; 4 838-843
Kataoka A‚ Takano H‚ Imaeda T‚ Lee K‚ Ueda M‚ Funabashi N‚ Oda S‚ Komuro I‚ Kobayashi Y. A case of fulminant myocarditis ultimately diagnosed by tenascin C staining.
Int J Cardiol 2011;
Takahashi A‚ Funabashi N‚ Kataoka A‚ Yajima R‚ Takahashi M‚ Uehara M‚ Takaoka H‚ Saito M‚ Yamaguchi C‚ Lee K‚ Komuro I‚ Nomura F. Quantitative evaluation of right atrial volume and right atrial emptying fraction by 320-slice computed tomography compared with three-dimensional echocardiography.
Int J Cardiol 2011; 146 96-99
Hara M‚ Mizote I‚ Nakaoka Y‚ Tanaka H‚ Asano Y‚ Sakata Y‚ Komuro I. A case of non-cardiogenic acute pulmonary edema in a patient with POEMS syndrome-associated pulmonary arterial hypertension.
Ann Hematol 2011; 90 489-490
Minamiguchi H‚ Nanto S‚ Onishi T‚ Watanabe T‚ Uematsu M‚ Komuro I. Low atrial septal pacing with dual-chamber pacemakers reduces atrial fibrillation in sick sinus syndrome.
J Cardiol 2011; 57 223-230
Hori Y‚ Tada H‚ Nakamura K‚ Naito S‚ Nakata Y‚ Goto K‚ Imamoto J‚ Yokokawa M‚ Tanaka Y‚ Funabashi N‚ Aonuma K‚ Komuro I‚ Taniguchi K‚ Oshima S. Presence of structural heart disease and left ventricular dysfunction predict hospitalizations for new-onset heart failure after right ventricular apical pacing.
Europace 2011; 13 230-236
Hashimoto T‚ Sakata Y‚ Fukushima K‚ Maeda T‚ Arita Y‚ Shioyama W‚ Nakaoka Y‚ Hori Y‚ Morii E‚ Aozasa K‚ Kanakura Y‚ Yamauchi-Takihara K‚ Komuro I. Pulmonary arterial hypertension associated with chronic active Epstein-Barr virus infection.
Intern Med 2011; 50 119-124
Aizawa Y‚ Sakata Y‚ Mano T‚ Takeda Y‚ Ohtani T‚ Tamaki S‚ Omori Y‚ Tsukamoto Y‚ Hirayama A‚ Komuro I‚ Yamamoto K. Transition from asymptomatic diastolic dysfunction to heart failure with preserved ejection fraction.
Circ J 2011; 75 596-602
Kadohira T‚ Kobayashi Y‚ Iwata Y‚ Kitahara H‚ Komuro I. Coronary Artery Endothelial Dysfunction Associated With Sleep Apnea.
Angiology 2011; 62 397-400
Kuramoto Y‚ Yamada T‚ Tamaki S‚ Okuyama Y‚ Morita T‚ Furukawa Y‚ Tanaka K‚ Iwasaki Y‚ Yasui T‚ Ueda H‚ Okada T‚ Kawasaki M‚ Levy WC‚ Komuro I‚ Fukunami M. Usefulness of Cardiac Iodine-123 Meta-Iodobenzylguanidine Imaging to Improve Prognostic Power of Seattle Heart Failure Model in Patients With Chronic Heart Failure.
Am J Cardiol 2011; 107 1185-1190
Ueda H‚ Yamada T‚ Masuda M‚ Okuyama Y‚ Morita T‚ Furukawa Y‚ Koji T‚ Iwasaki Y‚ Okada T‚ Kawasaki M‚ Kuramoto Y‚ Naito T‚ Fujimoto T‚ Komuro I‚ Fukunami M. Prevention of Contrast-Induced Nephropathy by Bolus Injection of Sodium Bicarbonate in Patients With Chronic Kidney Disease Undergoing Emergent Coronary Procedures.
Am J Cardiol 2011; 107 1163-1167
Yajima R‚ Kataoka A‚ Takahashi A‚ Uehara M‚ Saito M‚ Yamaguchi C‚ Lee K‚ Komuro I‚ Funabashi N. Distinguishing focal fibrotic lesions and non-fibrotic lesions in hypertrophic cardiomyopathy by assessment of regional myocardial strain using two-dimensional speckle tracking echocardiography: Comparison with multislice CT.
Int J Cardiol 2011;
Kawakubo M‚ Funabashi N‚ Takahashi M‚ Sueishi M‚ Motoyoshi Y‚ Mikata T‚ Uchida I‚ Asakawa T‚ Takahashi R‚ Takamatsu M‚ Matsuoka Y‚ Minegishi M‚ Naga H‚ Yajima R‚ Kataoka A‚ Lee K‚ Komuro I. Relationship of natriuretic peptide and transthoracic echocardiographic findings in 135 subjects with muscular dystrophy.
Int J Cardiol 2011; 145 506-514
Uehara M‚ Funabashi N‚ Ueda M‚ Murayama T‚ Takaoka H‚ Sawada K‚ Kasahara T‚ Yanagawa N‚ Komuro I. Quality of coronary arterial 320-slice computed tomography images compared with 16-slice computed tomography images in subjects with chronic atrial fibrillation.
Int J Cardiol 2011; 149 e90-93
Takahashi A‚ Funabashi N‚ Kataoka A‚ Yajima R‚ Takahashi M‚ Uehara M‚ Takaoka H‚ Saito M‚ Yamaguchi C‚ Lee K‚ Komuro I‚ Nomura F. Quantitative evaluation of right atrial volume and right atrial emptying fraction by 320-slice computed tomography compared with three-dimensional echocardiography.
Int J Cardiol 2011; 146 96-99
Narumi H‚ Takano H‚ Shindo S‚ Fujita M‚ Mizuma H‚ Kuwabara Y‚ Komuro I. Effects of valsartan and amlodipine on cardiorenal protection in Japanese hypertensive patients: the Valsartan Amlodipine Randomized Trial.
Hypertens Res 2011; 34 62-69
Kurotobi T‚ Iwakura K‚ Inoue K‚ Kimura R‚ Toyoshima Y‚ Ito N‚ Mizuno H‚ Shimada Y‚ Fujii K‚ Nanto S‚ Komuro I. The significance of the shape of the left atrial roof as a novel index for determining the electrophysiological and structural characteristics in patients with atrial fibrillation.
Europace 2011; 13 803-808
Takeda Y‚ Sakata Y‚ Mano T‚ Ohtani T‚ Kamimura D‚ Tamaki S‚ Omori Y‚ Tsukamoto Y‚ Aizawa Y‚ Komuro I‚ Yamamoto K. Competing risks of heart failure with preserved ejection fraction in diabetic patients.
Eur J Heart Fail 2011; 13 664-669
Kamimura D‚ Ohtani T‚ Sakata Y‚ Mano T‚ Takeda Y‚ Tamaki S‚ Omori Y‚ Tsukamoto Y‚ Furutani K‚ Komiyama Y‚ Yoshika M‚ Takahashi H‚ Matsuda T‚ Baba A‚ Umemura S‚ Miwa T‚ Komuro I‚ Yamamoto K.Motohashi‚ S.‚ Iwama‚ A.‚ and Nakayama‚ T. Ca2+ entry mode of Na+/Ca2+ exchanger as a new therapeutic target for heart failure with preserved ejection fraction.
Eur Heart J 2011;
Yamamoto R‚ Akazawa H‚ Fujihara H‚ Ozasa Y‚ Yasuda N‚ Ito K‚ Kudo Y‚ Qin Y‚ Ueta Y‚ Komuro I. Angiotensin II type 1 receptor signaling regulates feeding behavior through anorexigenic corticotropin-releasing hormone in hypothalamus.
J Biol Chem 2011; 286 21458-21465
Iwakura T‚ Mohri T‚ Hamatani T‚ Obana M‚ Yamashita T‚ Maeda M‚ Katakami N‚ Kaneto H‚ Oka T‚ Komuro I‚ Azuma J‚ Nakayama H‚ Fujio Y. STAT3/Pim-1 signaling pathway plays a crucial role in endothelial differentiation of cardiac resident Sca-1+ cells both in vitro and in vivo.
J Mol Cell Cardiol 2011; 51 207-214
Yamashita T‚ Iwakura T‚ Matsui K‚ Kawaguchi H‚ Obana M‚ Hayama A‚ Maeda M‚ Izumi Y‚ Komuro I‚ Ohsugi Y‚ Fujimoto M‚ Naka T‚ Kishimoto T‚ Nakayama H‚ Fujio Y. IL-6-mediated Th17 differentiation through RORγt is essential for the initiation of experimental autoimmune myocarditis.
Cardiovasc Res 2011; 91 640-648
Wu X‚ Zou Y‚ Zhou Q‚ Huang L‚ Gong H‚ Sun A‚ Tateno K‚ Katsube K‚ Radtke F‚ Ge J‚ Minamino T‚ Komuro I. Role of Jagged1 in arterial lesions after vascular injury.
Arterioscler Thromb Vasc Biol 2011; 31 2000-2006
Taneike M‚ Mizote I‚ Morita T‚ Watanabe T‚ Hikoso S‚ Yamaguchi O‚ Takeda T‚ Oka T‚ Tamai T‚ Oyabu J‚ Murakawa T‚ Nakayama H‚ Nishida K‚ Takeda J‚ Mochizuki N‚ Komuro I‚ Otsu K. Calpain protects the heart from hemodynamic stress.
J Biol Chem 2011; 286 32170-32177
Hasegawa H‚ Takano H‚ Narumi H‚ Ohtsuka M‚ Mizuguchi T‚ Namiki T‚ Kobayashi Y‚ Komuro I. Effects of telmisartan and losartan on cardiovascular protection in Japanese hypertensive patients.
Hypertens Res 2011; 34 1179-1184
Zou Y‚ Li J‚ Ma H‚ Jiang H‚ Yuan J‚ Gong H‚ Liang Y‚ Guan A‚ Wu J‚ Li L‚ Zhou N‚ Niu Y‚ Sun A‚ Nakai A‚ Wang P‚ Takano H‚ Komuro I‚ Ge J. Heat shock transcription factor 1 protects heart after pressure overload through promoting myocardial angiogenesis in male mice.
J Mol Cell Cardiol 2011; 51 821-829
Shiozaki M‚ Iso H‚ Ohira T‚ Nakatani D‚ Shimizu M‚ Sakata Y‚ Komuro I‚ Sato H. Longitudinal Risk of Cardiovascular Events in Relation to Depression Symptoms After Discharge Among Survivors of Myocardial Infarction.
Circ J 2011; 75 2878-2884
Masuda D‚ Sakai N‚ Sugimoto T‚ Kitazume-Taneike R‚ Yamashita T‚ Kawase R‚ Nakaoka H‚ Inagaki M‚ Nakatani K‚ Yuasa-Kawase M‚ Tsubakio-Yamamoto K‚ Ohama T‚ Nakagawa-Toyama Y‚ Nishida M‚ Ishigami M‚ Masuda Y‚ Matsuyama A‚ Komuro I‚ Yamashita S. Fasting Serum Apolipoprotein B-48 Can be a Marker of Postprandial Hyperlipidemia.
J Atheroscler Thromb 2011; 18 1062-1070
Hanada H‚ Mugii S‚ Okubo M‚ Maeda I‚ Kuwayama K‚ Hidaka Y‚ Kitazume-Taneike R‚ Yamashita T‚ Kawase R‚ Nakaoka H‚ Inagaki M‚ Yuasa-Kawase M‚ Nakatani K‚ Tsubakio-Yamamoto K‚ Masuda D‚ Ohama T‚ Matsuyama A‚ Ishigami M‚ Nishida M‚ Komuro I‚ Yamashita S. Establishment of chemiluminescence enzyme immunoassay for apolipoprotein B-48 and its clinical applications for evaluation of impaired chylomicron remnant metabolism.
Clin Chim Acta 2011; 413 160-165
Zou Y‚ Liang Y‚ Gong H‚ Zhou N‚ Ma H‚ Guan A‚ Sun A‚ Wang P‚ Niu Y‚ Jiang H‚ Takano H‚ Toko H‚ Yao A‚ Takeshima H‚ Akazawa H‚ Shiojima I‚ Wang Y‚ Komuro I‚ Ge J. Ryanodine Receptor Type 2 Is Required for the Development of Pressure Overload-Induced Cardiac Hypertrophy.
J. Hypertension 2011; 58 1099-1110
Takano H‚ Hasegawa H‚ Narumi H‚ Shindo S‚ Mizuma H‚ Kuwabara Y‚ Kobayashi Y‚ Komuro I. Effects of valsartan and amlodipine on home blood pressure and cardiovascular events in Japanese hypertensive patients: a subanalysis of the VART.
J Hum Hypertens 2011;
Ippei Shimizu‚ Yohko Yoshida‚ Taro Katsuno‚ Kaoru Tateno‚ Sho Okada‚ Junji Moriya‚ Masataka Yokoyama‚ Aika Nojima‚ Takashi Ito‚ Rudolf Zechner‚ Issei Komuro‚ Yoshio Kobayashi‚ Tohru Minamino p53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure.
Cell Metabolism 2011; 15 (1): 51-64
Hoshino A‚ Ishii G‚ Ito T‚ Aoyagi K‚ Ohtaki Y‚ Nagai K‚ Sasaki H‚ Ochiai A. Podoplanin-positive fibroblasts enhance lung adenocarcinoma tumor formation.
Cancer Res. 2011; 71 (14): 4769-4779
Nomura S‚ Taki F‚ Tamagaki K‚ Futatsuyama M‚ Nishihara S‚ Anzai H‚ Nishi Y‚ Takao N‚ Hayashida N‚ Komatsu Y. Renal outcome of contrast-induced nephropathy after coronary angiography in patients with chronic kidney disease.
Int J Cardiol 2011; 146 (2): 295-296
Miyazaki S‚ Funabashi N‚ Nagai T‚ Uehara M‚ Kataoka A‚ Takaoka H‚ Ueda M‚ Komuro I. Cardiac sarcoidosis complicated with atrioventricular block and wall thinning‚ edema and fibrosis in left ventricle: Confirmed recovery to normal sinus rhythm and visualization of edema improvement by administration of predonisolone.
Int J Cardiol. 2011; 150 (1): e974-10
Nakamura K‚ Funabashi N‚ Uehara M‚ Ueda M‚ Murayama T‚ Takaoka H‚ Komuro I. Left atrial wall thickness in paroxysmal atrial fibrillation by multislice-CT is initial marker of structural remodeling and predictor of transition from paroxysmal to chronic form.
Int J Cardiol. 2011; 148 (2): 139-147
Kudo K‚ Funabashi N‚ Uehara M‚ Murayama T‚ Yajima R‚ Hayakawa N‚ Ueda M‚ Takaoka H‚ Komuro I. Reversible left ventricular wall thickening during recovery procedure in takotsubo cardiomyopathy demonstrated by multislice computed tomography.
Int J Cardiol. 2011; 149 (3): e97-99
Uehara M‚ Funabashi N‚ Miyagi J‚ Suzuki M‚ Sekine T‚ Takaoka H‚ Takahashi K‚ Komuro I. Comparison of three techniques for evaluation of de novo asymptomatic pulmonary arterial thrombosis following deep vein thrombosis in total knee arthroplasty.
Int J Cardiol. 2011; 148 (1): 11-16
Uehara M‚ Tanabe N‚ Funabashi N‚ Takaoka H‚ Ikari J‚ Toyama S‚ Shimizu H‚ Hoshino S‚ Sugiura T‚ Saito M‚ Kawata N‚ Matsuura Y‚ Kuriyama T‚ Tatsumi K‚ Komuro I. Detailed distribution of acute pulmonary thromboemboli: Direct evidence for reduction of acquisition length and radiation dose for triple rule-out CT angiography.
Int J Cardiol. 2011; 147 (2): 234-238
Uehara M‚ Funabashi N‚ Ueda M‚ Murayama T‚ Takaoka H‚ Sawada K‚ Kasahara T‚ Yanagawa N‚ Komuro I. Quality of coronary arterial 320-slice computed tomography images in subjects with chronic atrial fibrillation compared with normal sinus rhythm.
Int J Cardiol. 2011; 150 (1): 65-70
International Conferences
Komuro I Molecular mechanisms of diabetes and diabetic vasculopathy.
SIRIC International Symposium 2011 2011-6-1 Seoul/Korea
Komuro I Molecular Mechanisms and Novel Treatments of Heart Failure
The Korean Society of Cardiology 2011-12-3 Daejeon/Korea
Komuro I "p53 inhibits angiogenesis "
The Second Pacific Symposium on Vascular Biology 2011-10-30 Jeju Island/Korea
Komuro I Harmful Effects of Excenssive lnsulin Signaling in a Setting of Pressure Overload
American Heart Association 2011 2011-10-12 Orlando/USA
