Research Achievements

Issei Komuro

2012 | 2011 | 2010 | 2009 | 2008 |
| Papers| International Conferences |

Papers

Ma H‚ Gong H‚ Chen Z‚ Liang Y‚ Yuan J‚ Zhang G‚ Wu J‚ Ye Y‚ Yang C‚ Nakai A‚ Komuro I‚ Ge J‚ Zou Y.   Association of Stat3 with HSF1 plays a critical role in G-CSF-induced cardio-protection against ischemia/reperfusion injury.
J Mol Cell Cardiol  2012;     


Iwashita M‚ Sakoda H‚ Kushiyama A‚ Fujishiro M‚ Ohno H‚ Nakatsu Y‚ Fukushima T‚ Kumamoto S‚ Tsuchiya Y‚ Kikuchi T‚ Kurihara H‚ Akazawa H‚ Komuro I‚ Kamata H‚ Nishimura F‚ Asano T.   Valsartan‚ independently of AT1 receptor or PPAR¦Ã‚ suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes.
Am J Physiol Endocrinol Metab  2012;  302     E286-296


Fukushima N‚ Matsuura K‚ Akazawa H‚ Honda A‚ Nagai T‚ Takahashi T‚ Seki A‚ Murasaki KM‚ Shimizu T‚ Okano T‚ Hagiwara N‚ Komuro I.   A crucial role of activin A-mediated growth hormone suppression in mouse and human heart failure.
PLoS One  2012;  6e27901    


Yasuda N‚ Akazawa H‚ Ito K‚ Shimizu I‚ Kudo-Sakamoto Y‚ Yabumoto C‚ Yano M‚ Yamamoto R‚ Ozasa Y‚ Minamino T‚ Naito AT‚ Oka T‚ Shiojima I‚ Tamura K‚ Umemura S‚ Nemer M‚ Komuro I.   Agonist-Independent Constitutive Activity of Angiotensin II Receptor Promotes Cardiac Remodeling in Mice.
Hypertension  2012;     


Sakata Y‚ Nakatani D‚ Shimizu M‚ Suna S‚ Usami M‚ Matsumoto S‚ Hara M‚ Sumitsuji S‚ Kawano S‚ Iwakura K‚ Hamasaki T‚ Sato H‚ Nanto S‚ Hori M‚ Komuro I.   Oral treatment with nicorandil at discharge is associated with reduced mortality after acute myocardial infarction.
J Cardiol  2012;  59     14-21


Okada S‚ Yokoyama M‚ Toko H‚ Tateno K‚ Moriya J‚ Shimizu I‚ Nojima A‚ Ito T‚ Yoshida Y‚ Kobayashi Y‚ Katagiri H‚ Minamino T‚ Komuro I   Brain-Derived Neurotrophic Factor Protects Against Cardiac Dysfunction After Myocardial Infarction via a Central Nervous System-Mediated Pathway.
Arterioscler Thromb Vasc Biol.  2012;  in press    


Naito AT‚ Sumida T‚ Nomura S‚ Liu ML‚ Higo T‚ Nakagawa A‚ Okada K‚ Sakai T‚ Hashimoto A‚ Hara Y‚ Shimizu I‚ Zhu W‚ Toko H‚ Katada A‚ Akazawa H‚ Oka T‚ Lee JK‚ Minamino T‚ Nagai T‚ Walsh K‚ Kikuchi A‚ Matsumoto M‚ Botto M‚ Shiojima I‚ Komuro I   Complement c1q activates canonical wnt signaling and promotes aging-related phenotypes.
Cell Metab  2012;  149   (6):   1298-1313


Kameda Y‚ Hasegawa H‚ Kubota A‚ Tadokoro H‚ Kobayashi Y‚ Komuro I‚ Takano H.   Effects of pitavastatin on pressure overload-induced heart failure in mice.
Circ J.  2012;  76   (5):   1159-1168


Uchiyama R‚ Hasegawa H‚ Kameda Y‚ Ueda K‚ Kobayashi Y‚ Komuro I‚ Takano H.   Role of regulatory T cells in atheroprotective effects of granulocyte colony-stimulating factor.
J Mol Cell Cardiol  2012;  52   (5):   1038-1047


Hasegawa H‚ Takano H‚ Kameda Y‚ Kubota A‚ Kobayashi Y‚ Komuro I.   Effect of switching from telmisartan‚ valsartan‚ olmesartan‚ or losartan to candesartan on morning hypertension.
Clin Exp Hypertens.  2012;  34   (2):   86-91


Shimizu I‚ Yoshida Y‚ Katsuno T‚ Tateno K‚ Okada S‚ Moriya J‚ Yokoyama M‚ Nojima A‚ Ito T‚ Zechner R‚ Komuro I‚ Kobayashi Y‚ Minamino T.   p53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure.
Cell Metab  2012;  15   (1):   51-64


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International Conferences

Issei Komuro Wnts in development in other pathways¡ÈComplement C1q activates canonical Wnt signaling and¡¡Promotes aging-related phenotypes 
EMBO Conference : 30 Years of Wnt Signalling 2012-6-27 Egmond aan Zee/Netherlands


Issei Komuro Angiogenesis and heart failure 
17th International Vascular Biology Meeting 2012-6-2 Wiesbaden/Germany


Ito. T CDC42 and NF¦ÊB signaling contribute to pro-inflammatory phenotype of senescent endothelial cells 
41st Annual Meeting of The American Aging Association 2012-5-31 Dallas/USA


Ito. T CDC42 and NF¦ÊB signaling contribute to pro-inflammatory phenotype of senescent endothelial cells 
Keystone Symposia symposium:Molecular Basis of Vascular Inflammation and Atherosclerosis (C7) 2012-3-25 Big Sky/USA


Yoshida Y‚ Minamino T Notch signaling positively regulates vascular endothelial cell senescence 
Gordon Research Conference‚ Aging‚ Biology of 2012-2-12 Ventura/USa


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